Blar i NTNU Open på forfatter "Johnsen, Ingvild Bjellmo"
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Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection
Loevenich, Simon; Malmo, Jostein; Liberg, Ann Magritt; Sherstova, Tatyana; Li, Youxian; Rian, Kristin; Johnsen, Ingvild Bjellmo; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2019)Human metapneumovirus (HMPV) may cause severe respiratory disease. The early innate immune response to viruses like HMPV is characterized by induction of antiviral interferons (IFNs) and proinflammatory immune mediators ... -
Characterization of innate immune signaling components involved in regulation of TSLP expression in airway cells upon human metapneumovirus infection
Nervik, Ida Haugan (Master thesis, 2016)Viral respiratory tract infections have been linked to development of asthma, which affects approximately 235 million people around the world. Human metapneumovirus (hMPV) is a recently discovered virus recognized as a ... -
Characterization of signaling pathways regulating the expression of pro-inflammatory long form thymic stromal lymphopoietin upon human metapneumovirus infection
Li, Youxian; Lund, Cecilie; Nervik, Ida; Loevenich, Simon; Døllner, Henrik; Anthonsen, Marit Walbye; Johnsen, Ingvild Bjellmo (Journal article; Peer reviewed, 2018)Thymic stromal lymphopoietin (TSLP) is associated with several allergic diseases including asthma. Two isoforms of TSLP exist in humans, a long form (lfTSLP) and a short form (sfTSLP), displaying distinct immunological ... -
Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis
Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo; Espevik, Terje; Nordbø, Svein Arne; Døllner, Henrik; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2016)Human metapneumovirus (hMPV) causes severe airway infection in children that may be caused by an unfavorable immune response. The nature of the innate immune response to hMPV in naturally occurring infections in children ... -
Exploring the hepatitis C virus encoded protease NS3/4A in relation to Autophagy
Leirvik, Gunnhild Vatne (Master thesis, 2011)Autophagy is an evolutionarily conserved intracellular bulk degradation system essential for the cell homeostasis. In addition, autophagy is emerging as a central component in viral host defense. Many pathogens have evolved ... -
Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ
Kurena, Baiba; Müller, Elisabeth; Christopoulos, Panagiotis; Johnsen, Ingvild Bjellmo; Stankovic, Branislava; Øynebråten, Inger; Corthay, Alexandre; Zajakina, Anna (Journal article; Peer reviewed, 2017)Cytokine gene delivery by viral vectors is a promising novel strategy for cancer immunotherapy. Semliki Forest virus (SFV) has many advantages as a delivery vector, including the ability to (i) induce p53-independent killing ... -
Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M
Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Sherstova, Tatyana; Wakita, Takaji; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Meurs, Eliane F.; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2017)Positive-stranded RNA viruses, such as hepatitis C virus (HCV), assemble their viral replication complexes by remodeling host intracellular membranes to a membranous web. The precise composition of these replication complexes ... -
Human Metapneumovirus Infection Inhibits Cathelicidin Antimicrobial Peptide Expression in Human Macrophages
Li, Youxian; Østerhus, Stine; Johnsen, Ingvild Bjellmo (Journal article; Peer reviewed, 2018)Human cathelicidin antimicriobial peptide (CAMP) is a critical component of host innate immunity with both antimicrobial and immunomodulatory functions. Several pathogens have been shown to downregulate CAMP expression, ... -
Intracellular signaling mechanisms in the innate immune response to viral infections
Johnsen, Ingvild Bjellmo (Doktoravhandlinger ved NTNU, 1503-8181; 2009:120, Doctoral thesis, 2009) -
Novel insights into the innate immune responses to human metapneumovirus infection or changes in osmolality
Li, Youxian (Doctoral theses at NTNU;2018:323, Doctoral thesis, 2018)Ny innsikt i de medfødte immunresponsene mot humant metapneumovirus infeksjon eller endringer i osmolalitet Sammendraget: Kroppens medfødte immunsystem gir umiddelbar beskyttelse mot infeksjoner og styrer de påfølgende ... -
The Role of Mitochondrial Antiviral Signaling Protein (MAVS) in Mitochondrial Funtions
Skjærbusdal, Kine (Master thesis, 2012)Infectious diseases account for more than 13 million deaths every year, which makes it apparent that infectious diseases are a tremendous burden for the society. Much research has therefore been aimed to elucidate the ... -
Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood
Dong, Zihan; Myklebust, Åsne; Johnsen, Ingvild Bjellmo; Jartti, Tuomas; Døllner, Henrik; Risnes, Kari Ravndal; Dewan, Andrew (Journal article; Peer reviewed, 2023)