• Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2 

      Wagoner, Jessica; Herring, Shawn; Hsiang, Tien-Ying; Ianevski, Aleksandr; Biering, Scott B.; Xu, Shuang; Hoffmann, Markus; Pöhlmann, Stefan; Gale, Michael; Aittokallio, Tero Antero; Schiffer, Joshua T.; White, Judith M.; Polyaka, Stephen J. (Peer reviewed; Journal article, 2022)
      Three directly acting antivirals (DAAs) demonstrated substantial reduction in COVID-19 hospitalizations and deaths in clinical trials. However, these agents did not completely prevent severe illness and are associated with ...