Blar i NTNU Open på forfatter "Eldholm, Rannveig Sakshaug"

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    • Alzheimer's Disease - The Impact of Vascular Comorbidity on Disease Progression and Clinical Profile 

      Eldholm, Rannveig Sakshaug (Doctoral theses at NTNU;2019:77, Doctoral thesis, 2019)

    • Applicability of the locus of control of behaviour scale for people with dementia 

      Halse, Ingeborg; Björklöf, Guro Hanevold; Engedal, Knut; Rokstad, Anne Marie Mork; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Selbæk, Geir; Barca, Maria Lage (Journal article; Peer reviewed, 2019)
      Objective: To investigate the applicability of the Locus of Control of Behaviour scale (LoCB) for people with dementia. Method: A sample of 534 participants with dementia (78.4 mean age, 58% female) were included. Assessment ...

    • Association between vascular comorbidity and progression of Alzheimer's disease: a two-year observational study in Norwegian memory clinics 

      Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Barca, Maria Lage; Knapskog, Anne Brita; Cavallin, Lena; Engedal, Knut; Skovlund, Eva; Saltvedt, Ingvild; Selbaek, Geir (Journal article; Peer reviewed, 2018)
      Background: Vascular risk factors increase the risk of Alzheimer’s disease (AD), but there is limited evidence on whether comorbid vascular conditions and risk factors have an impact on disease progression. The aim of this ...

    • Assosiasjoner mellom ganghastighet og kognitiv funksjon hos personer som utredes for kognitiv svikt i spesialisthelsetjenesten 

      Sjøgren, Nina Almåsstø (Master thesis, 2022)
      Bakgrunn: Risikoen for utvikling av demens stiger med alderen. På grunn av en aldrende befolkning er forekomsten av demens er økende. Befolkningsundersøkelser estimerer at i år 2050 vil det leve rundt 235 000 personer med ...

    • Brain Morphometric Correlates of Depressive Symptoms among Patients with and without Dementia 

      Barca, Maria Lage; Alnæs, Dag; Engedal, Knut; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Siafarikas, Nikias Ioannis; Almdahl, Ina Selseth; Korsnes, Maria Stylianou; Saltvedt, Ingvild; Selbæk, Geir; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2022)
      Introduction: Findings regarding brain morphometry among patients with dementia and concomitant depressive symptoms have been inconsistent. Thus, the aim of the present study was to test the hypothesis that dementia and ...

    • Cerebrospinal fluid catecholamines in Alzheimer's disease patients with and without biological disease 

      Henjum, Kristi; Watne, Leiv; Godang, Kristin; Halaas, Nathalie Bodd; Eldholm, Rannveig Sakshaug; Blennow, Kaj; Zetterberg, Henrik; Saltvedt, Ingvild; Bollerslev, Jens; Knapskog, Anne Brita (Journal article; Peer reviewed, 2022)
      Noradrenergic and dopaminergic neurons are involved in cognitive functions, relate to behavioral and psychological symptoms in dementia and are affected in Alzheimer’s disease (AD). Amyloid plaques (A), neurofibrillary ...

    • Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification 

      Knapskog, Anne Brita; Henjum, Kristi; Idland, Ane-Victoria; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Saltvedt, Ingvild; Watne, Leiv; Engedal, Knut; Nilsson, Lars N.G. (Peer reviewed; Journal article, 2020)
      Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ...

    • Change in physical activity and systolic blood pressure trajectories throughout mid-life and the development of dementia in older age: the HUNT study 

      Lerfald, Maren; Lydersen, Stian; Zotcheva, Ekaterina; Nilsen, Tom Ivar Lund; Eldholm, Rannveig Sakshaug; Martinez-Velilla, Nicolás; Selbæk, Geir; Ernstsen, Linda (Peer reviewed; Journal article, 2023)
      Background There is lack of research on combinations of possible modifiable risk factors for dementia in a life-time perspective. Dementia has currently no cure, and therefore new knowledge of preventive factors is ...

    • Cortisol levels among older people with and without depression and dementia 

      Barca, Maria Lage; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Björklöf, Guro Hanevold; Borza, Tom; Telenius, Elisabeth Wiken; Knapskog, Anne-Brita; Brækhus, Anne; Saltvedt, Ingvild; Selbæk, Geir; Engedal, Knut (Journal article; Peer reviewed, 2018)
      Cortisol dysregulation has been reported in dementia and depression. Cortisol levels and its associates were investigated among older people living at home and in nursing homes, in a cross-sectional study. A sample of 650 ...

    • Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients 

      Knapskog, Anne Brita; Eldholm, Rannveig Sakshaug; Brækhus, Anne; Engedal, Knut; Saltvedt, Ingvild (Journal article; Peer reviewed, 2017)
      Background The cerebrospinal fluid (CSF) biomarkers amyloid β (Aβ), phospho tau (P-tau) and total tau (T-tau) are used increasingly to support a clinical diagnosis of Alzheimer’s disease. The diagnostic power of these ...

    • A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease 

      Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Peer reviewed; Journal article, 2020)
      Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...

    • Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease 

      Knapskog, Anne Brita; Aksnes, Mari; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Saltvedt, Ingvild Tina; Solvang, Stein-Erik Hafstad; Watne, Leiv (Peer reviewed; Journal article, 2023)
      INTRODUCTION The kynurenine pathway's (KP) malfunction is closely related to Alzheimer's disease (AD), for antagonistic kynurenic acid (KA) and agonistic quinolinic acid act on the N-methyl-D-aspartate receptor, a ...

    • The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study 

      Aam, Stina; Gynnild, Mari Nordbø; Munthe-Kaas, Ragnhild; Saltvedt, Ingvild; Lydersen, Stian; Knapskog, Anne Brita; Ihle-Hansen, Hege; Ellekjær, Hanne; Eldholm, Rannveig Sakshaug; Fure, Brynjar (Peer reviewed; Journal article, 2021)
      Introduction: Post-stroke cognitive impairment (PSCI) is common, but evidence on the impact of vascular risk factors is lacking. We explored the association between pre-stroke vascular risk factors and PSCI and studied the ...

    • A Machine Learning Approach to Predict Post-stroke Fatigue. The Nor-COAST study 

      Luzum, Geske; Thrane, Gyrd; Aam, Stina; Eldholm, Rannveig Sakshaug; Grambaite, Ramune; Munthe-Kaas, Ragnhild; Thingstad, Anne Pernille Mæhle; Saltvedt, Ingvild; Askim, Torunn (Journal article; Peer reviewed, 2014)
      Objective: This study aimed to predict fatigue 18 months post-stroke by utilizing comprehensive data from the acute and sub-acute phases after stroke in a machine-learning set-up. Design: A prospective multicenter ...

    • MRI-assessed atrophy subtypes in Alzheimer’s disease and the cognitive reserve hypothesis 

      Persson, Karin; Eldholm, Rannveig Sakshaug; Barca, Maria Lage; Cavallin, Lena; Ferreira, Daniel; Knapskog, Anne Brita; Selbæk, Geir; Brækhus, Anne; Saltvedt, Ingvild; Westman, Eric; Engedal, Knut (Journal article; Peer reviewed, 2017)
      Background/Aims MRI assessment of the brain has demonstrated four different patterns of atrophy in patients with Alzheimer’s disease dementia (AD): typical AD, limbic-predominant AD, hippocampal-sparing AD, and a subtype ...

    • Progression of Alzheimer's Disease: A Longitudinal Study in Norwegian Memory Clinics 

      Eldholm, Rannveig Sakshaug; Barca, Maria Lage; Persson, Karin; Knapskog, Anne-Brita; Kersten, Hege; Engedal, Knut; Selbæk, Geir; Brækhus, Anne; Skovlund, Eva; Saltvedt, Ingvild (Journal article; Peer reviewed, 2017)
      Background: The course of Alzheimer’s disease (AD) varies considerably between individuals. There is limited evidence on factors important for disease progression. Objective: The primary aim was to study the progression ...

    • Sex-specific associations of matrix metalloproteinases in Alzheimer’s disease 

      Aksnes, Mari; Edwin, Trine Holt; Saltvedt, Ingvild Tina; Eldholm, Rannveig Sakshaug; Chaudhry, Farrukh Abbas; Halaas, Nathalie Bodd; Myrstad, Marius; Watne, Leiv; Knapskog, Anne Brita (Peer reviewed; Journal article, 2023)
      Introduction Alzheimer’s disease (AD) can be characterised in vivo by biomarkers reflecting amyloid-β (Aβ) and tau pathology. However, there is a need for biomarkers reflecting additional pathological pathways. Matrix ...

    • Språkfunksjon etter hjerneslag. En oppfølgingsstudie over tre år. 

      Myklebust, Guro; Elgaaen, Peder Sethne (Master thesis, 2023)
      Bakgrunn: Hvert år rammes omtrent ti tusen personer av akutt hjerneslag i Norge. En stor andel vil i forløpet oppleve at språket påvirkes, ofte i form av afasi eller dysartri. Det er rapportert ulike prognoser for slagrammede ...

    • Språkfunksjon etter hjerneslag. En oppfølgingsstudie over tre år. 

      Myklebust, Guro; Elgaaen, Peder Sethne (Master thesis, 2023)
      Bakgrunn: Hvert år rammes omtrent ti tusen personer av akutt hjerneslag i Norge. En stor andel vil i forløpet oppleve at språket påvirkes, ofte i form av afasi eller dysartri. Det er rapportert ulike prognoser for slagrammede ...

    • Trajectories of depressive symptoms and their relationship to the progression of dementia 

      Barca, Maria Lage; Persson, Karin; Eldholm, Rannveig Sakshaug; Saltyte Benth, Jurate; Kersten, Hege; Knapskog, Anne-Brita; Saltvedt, Ingvild; Selbæk, Geir; Engedal, Knut (Journal article; Peer reviewed, 2017)
      Background The relationship between progression of Alzheimer's disease and depression and its underlying mechanisms has scarcely been studied. Methods A sample of 282 outpatients with Alzheimer's disease (AD; 105 with ...