Blar i NTNU Open på forfatter "Sandvig, Axel"
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Smart and Multifunctional Core-Shell Nanoparticles (NPs) for Drug Delivery
Bandyopadhyay, Sulalit (Doctoral theses at NTNU;2016:294, Doctoral thesis, 2016)Nanomaterials designed for drug delivery applications require important properties that include monodispersity, biocompatibility, long circulation time which are dependent on size, shape, composition, surface charge among ... -
Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks
Valderhaug, Vibeke Devold; Huse Ramstad, Ola; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna (Journal article, 2020)Mutations in the LRRK2 gene have been widely linked to Parkinson’s disease. The G2019S variant has been shown to contribute uniquely to both familial and sporadic forms of the disease. LRRK2-related mutations have been ... -
Structural and functional dynamics of healthy and perturbed neuronal networks in vitro
Weir, Janelle Shari (Master thesis, 2019)Rapid advancement in the field of morphogenic neuroengineering has led to interesting research perspectives in the area of in vitro neural network modeling using human induced pluripotent stem cell (hiPSC) derived neural ... -
Structural Effects on the Computational Capacity of Neural Networks
Bjugn, Isak Kyrre Lichtwarck (Master thesis, 2020)Måten nevroner er forbundet til hverandre har stor påvirkning på et nevralt nettverks evne til å utføre beregninger. Akkurat slike beregninger er sentrale for funksjonen til sentralnervesystemet, og er en global egenskap ... -
Structure-function relationships in biological neural networks and the influence of neurodegenerative processes on such dynamics
Valderhaug, Vibeke Devold (Doctoral theses at NTNU;2020:77, Doctoral thesis, 2020) -
Structuring a multi-nodal neural network in vitro within a novel design microfluidic chip
van de Wijdeven, Rosanne; Huse Ramstad, Ola; Bauer, Ulrich Stefan; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna (Journal article; Peer reviewed, 2018)Neural network formation is a complex process involving axon outgrowth and guidance. Axon guidance is facilitated by structural and molecular cues from the surrounding microenvironment. Micro-fabrication techniques can be ... -
Synthesis and in vitro cellular interactions of superparamagnetic iron nanoparticles with a crystalline gold shell
Bandyopadhyay, Sulalit; Singh, Gurvinder; Sandvig, Ioanna; Sandvig, Axel; Mathieu, Roland; Kumar, P Anil; Glomm, Wilhelm (Journal article; Peer reviewed, 2014)Fe@Au core–shell nanoparticles (NPs) exhibit multiple functionalities enabling their effective use in applications such as medical imaging and drug delivery. In this work, a novel synthetic method was developed and optimized ... -
Tailored microfluidic platforms for advanced neurobiology, neuroengineering and electrophysiology
van de Wijdeven, Rosanne (Doctoral theses at NTNU;2019:135, Doctoral thesis, 2019) -
Towards Making a Cyborg: A Closed-Loop Reservoir-Neuro System
Aaser, Peter; Knudsen, Martinius; Huse Ramstad, Ola; van de Wijdeven, Rosanne; Nichele, Stefano; Sandvig, Ioanna; Tufte, Gunnar; Bauer, Ulrich Stefan; Halaas, Øyvind; Hendseth, Sverre; Sandvig, Axel; Valderhaug, Vibeke Devold (Chapter; Peer reviewed, 2017)The human brain is a remarkable computing machine, i.e. vastly parallel, self-organizing, robust, and energy efficient. To gain a better understanding into how the brain works, a cyborg (cybernetic organism, a combination ... -
Using microdialysis to administer and assess drugs aimed at attenuating Alzheimer’s disease-related neuropathology
Hemler, Mary Elizabeth (Master thesis, 2021)Alzheimer’s disease is the most common form of dementia and is characterized by the neuropathological hallmarks amyloid-β and neurofibrillary tangles. Despite tremendous efforts in understanding the molecular, pathophysiological, ... -
Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing
Bauer, Ulrich Stefan; Fiskum, Vegard; Nair Raveendran, Rajeevkumar; Wijdeven, Rosanne Francisca van de; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel (Peer reviewed; Journal article, 2022)Current preclinical models of neurodegenerative disease, such as amyotrophic lateral sclerosis (ALS), can significantly benefit from in vitro neuroengineering approaches that enable the selective study and manipulation of ... -
Viewing Rate-Based Neurons as Biophysical Conductance Outputting Models
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel (Journal article; Peer reviewed, 2019)In the field of computational neuroscience, spiking neural network models are generally preferred over rate-based models due to their ability to model biological dynamics. Within AI, rate-based artificial neural networks ...