Blar i NTNU Open på forfatter "Opdahl, Signe"
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Microvascular proliferation in luminal A and basal-like breast cancer subtypes
Kraby, Maria Ryssdal; Krüger, Kristi; Opdahl, Signe; Vatten, Lars Johan; Akslen, Lars A.; Bofin, Anna M. (Journal article; Peer reviewed, 2015)Aims The aims of this study were to examine microvessel density (MVD), proliferating MVD (pMVD) and Vascular Proliferation Index (VPI) in basal-like phenotype (BP) and luminal A subtypes of breast cancer and to study their ... -
Molecular subtypes of breast cancer: incidence and prognosis
Valla, Marit (Doctoral theses at NTNU;2017:276, Doctoral thesis, 2017)Forekomsten av brystkreft har over flere tiår økt i den vestlige verden, og i Norge har det vært en dobling av insidensen siden Kreftregisteret startet sin overvåkning av antall krefttilfeller i Norge i 1952. I Norge har ... -
Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences
Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe (Journal article; Peer reviewed, 2016)Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of 52,949 ... -
Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients
Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. (Peer reviewed; Journal article, 2013)Molecular subtyping of breast cancer may provide additional prognostic information regarding patient outcome. However, its clinical significance remains to be established. In this study, the main aims were to discover ... -
Mortality among young adults born preterm and early term in 4 Nordic nations
Risnes, Kari; Bilsteen, Josephine Funck; Brown, Paul; Pulakka, Anna; Andersen, Anne-Marie Nybo; Opdahl, Signe; Kajantie, Eero Olavi; Sandin, Sven (Peer reviewed; Journal article, 2021)Importance Adverse long-term outcomes in individuals born before full gestation are not confined to individuals born at extreme gestational ages. Little is known regarding mortality patterns among individuals born in the ... -
MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes
Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary; Valla, Marit (Peer reviewed; Journal article, 2020)Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 ... -
The neurodevelopmental morbidity of children born after assisted reproductive technology: a Nordic register study from the Committee of Nordic Assisted Reproductive Technology and Safety group
Rönö, Kristiina; Rissanen, Essi; Bergh, Christina; Wennerholm, Ulla-Britt; Opdahl, Signe; Romundstad, Liv Bente Bergem; Henningsen, Anna-Karina Aaris; Spangmose, Anne Lærke; Pinborg, Anja; Gissler, Mika; Tiitinen, Aila (Peer reviewed; Journal article, 2022)Objective To assess the risk of neurodevelopmental disorders in singletons born after the use of assisted reproductive technology (ART) compared with singletons born without the use of ART. Design Nordic register-based ... -
Non-progressive breast carcinomas detected at mammography screening: a population study
Heggland, Torunn; Vatten, Lars Johan; Opdahl, Signe; Weedon-Fekjær, Harald (Peer reviewed; Journal article, 2023)Background Some breast carcinomas detected at screening, especially ductal carcinoma in situ, may have limited potential for progression to symptomatic disease. To determine non-progression is a challenge, but if all ... -
Obesity and health in pregnancies after assisted reproductive technology
Johannessen, Heidi Grue (Master thesis, 2017)Objective: To compare the association of maternal pre-pregnancy body mass index (BMI) with adverse perinatal and maternal outcomes in pregnancies following spontaneous and assisted conception in a large nation-wide cohort. ... -
Overvekt og fedme i Trøndelag 2019: Helsestatistikk-rapport nummer 11 fra HUNT4
Kvistad, Kyrre; Brandkvist, Maria; Vie, Gunnhild Åberge; Moa, Pål Fossland; Opdahl, Signe; Sliper, Jon Olav; Rangul, Vegar; Krokstad, Steinar; Eiksund, Sveinung Øystein; Molden, Thomas Hugaas; Karlsen, Håvard Rudi; Jensberg, Heidi; Sund, Erik Reidar (Research report, 2023) -
Perinatal outcomes after assisted reproductive technology. Are adverse perinatal outcomes after assisted reproductive technology affected by mode of treatment or maternal factors?
Westvik-Johari, Kjersti (Doctoral theses at NTNU;2022:100, Doctoral thesis, 2022)Norsk sammendrag Perinatale utfall etter assistert befruktning. Er dårligere perinatal helse etter assistert befruktning et resultat av behandlingsmetode eller faktorer hos mor? Barn født etter assistert befruktning ... -
Pregnancy and breast cancer risk : prospective studies of Norwegian women
Opdahl, Signe (Doktoravhandlinger ved NTNU, 1503-8181; 2013:6, Doctoral thesis, 2013)Svangerskap og risiko for brystkreft: Prospektive studier av norske kvinner Brystkreft er den vanligste kreftformen blant kvinner i den vestlige verden. I Norge vil nær 10% av alle kvinner få sykdommen i løpet av livet. ... -
Puberty disorders among ART-conceived singletons: a Nordic register study from the CoNARTaS group
Klemetti, R.; Perry, B.; Henningsen, A K Aaris; Spangmose, A Lærke; Pinborg, A.; Opdahl, Signe; Romundstad, Liv Bente Bergem; Bergh, C.; Wennerholm, U.B.; Tiitinen, A.; Gissler, M. (Peer reviewed; Journal article, 2022)STUDY QUESTION Do ART-conceived children have an increased risk for puberty disorders? SUMMARY ANSWER Both ART-conceived boys and girls had a higher risk of puberty disorders; early puberty was more common among girls ... -
Quantifying tumour vascularity in non-luminal breast cancers
Kraby, Maria Ryssdal; Opdahl, Signe; Akslen, Lars A.; Bofin, Anna M. (Journal article; Peer reviewed, 2017)Aims Microvessel density (MVD), proliferating MVD (pMVD) and vascular proliferation index (VPI) are methods used to quantify tumour vascularity in histopathological sections. In this study, we assessed MVD, pMVD and VPI ... -
Risk of Hypertensive Disorders in Pregnancy After Fresh and Frozen Embryo Transfer in Assisted Reproduction: A Population-Based Cohort Study With Within-Sibship Analysis
Petersen, Sindre Hoff; Westvik-Johari, Kjersti; Spangmose, Anne Lærke; Pinborg, Anja Bisgaard; Romundstad, Liv Bente Bergem; Bergh, Christina; Åsvold, Bjørn Olav; Gissler, Mika; Tiitinen, Aila; Wennerholm, Ulla-Britt; Opdahl, Signe (Peer reviewed; Journal article, 2022)Background: Frozen embryo transfer (frozen-ET) is increasingly common because of improved cryopreservation methods and elective freezing of all embryos. Frozen-ET is associated with higher risk of hypertensive disorders ... -
Risk of ovarian cancer in women who give birth after assisted reproductive technology (ART)—a registry-based Nordic cohort study with follow-up from first pregnancy
Sandvei, Marie Søfteland; Pinborg, Anja; Gissler, Mika; Bergh, Christina; Romundstad, Liv Bente Bergem; van Leeuwen, Flora E.; Spaan, Mandy; Tiitinen, Aila; Wennerholm, Ulla-Britt; Henningsen, Anna-Karina; Opdahl, Signe (Peer reviewed; Journal article, 2022)Background There is concern that assisted reproductive technology (ART) may increase ovarian cancer risk, but previous studies are inconclusive. We compared ovarian cancer risk for women who gave birth after ART vs ... -
Risk of stillbirth and neonatal death in singletons born after fresh and frozen embryo transfer: cohort study from the Committee of Nordic Assisted Reproduction Technology and Safety
Westvik-Johari, Kjersti; Lawlor, Deborah; Romundstad, Liv Bente Bergem; Bergh, Christina; Wennerholm, Ulla-Britt; Gissler, Mika; Henningsen, Anna-Karina Aaris; Håberg, Siri Eldevik; Tiitinen, Aila; Spangmose, Anne Lærke; Pinborg, Anja Bisgaard; Opdahl, Signe (Peer reviewed; Journal article, 2022)Main Outcome Measure(s) Stillbirth (fetal death before and during delivery) and neonatal death (live born with death 0–27 days postpartum). Result(s) Overall, 17,123 (0.37%) singletons were stillborn and 7,685 (0.17%) ... -
Risk of stroke the year following a delivery after using assisted reproductive technologies
Magnus, Maria Christine; Håberg, Siri Eldevik; Rönö, Kristiina; Romundstad, Liv Bente Bergem; Bergh, Christina; Spangmose, Anne Lærke; Pinborg, Anja; Gissler, Mika; Wennerholm, Ulla-Britt; Opdahl, Signe (Peer reviewed; Journal article, 2023)Background Studies indicate that individuals who deliver after assisted reproductive technologies (ART) may have an increased risk of cardiovascular disease (CVD). A recent large study from the U.S. showed a higher risk ... -
Risk of thyroid cancer in women who give birth after treatment with assisted reproductive technology in the Nordic countries – a registry-based cohort study
Petersen, Sindre Hoff (Master thesis, 2020)Bakgrunn: På verdensbasis har risikoen for kreft i skjoldbruskkjertelen økt de siste tiårene. Kvinner har høyere risiko enn menn, særlig i alderen 30-50 år, noe som tyder på at hormonelle faktorer kan spille en rolle i ... -
Separating parental and treatment contributions to perinatal health after fresh and frozen embryo transfer in assisted reproduction: A cohort study with within-sibship analysis
Westvik-Johari, Kjersti; Romundstad, Liv Bente; Lawlor, Deborah A.; Bergh, Christina; Gissler, Mika; Henningsen, Anna-Karina A.; Håberg, Siri Eldevik; Wennerholm, Ulla-Britt; Tiitinen, Aila; Pinborg, Anja; Opdahl, Signe (Peer reviewed; Journal article, 2021)Background Compared to naturally conceived children, adverse perinatal outcomes are more common among children born after assisted reproductive technology with fresh embryo transfer (fresh-ET) or frozen embryo transfer ...