Now showing items 21-40 of 42

    • How does the grid scale support accurate spatial memory and navigation? 

      Wåga, Torgeir (Master thesis, 2013)
      How does the grid scale support accurate spatial memory and navigation? This critical piece of the puzzle is currently missing from experimental work on grid cells. Previous research has demonstrated that the medial ...
    • Integrating time from experience in the lateral entorhinal cortex 

      Moser, Edvard Ingjald; Tsao, Albert; Sugar, Jørgen; Wang, Cheng-Cheng; Moser, May-Britt; Knierim, James (Journal article; Peer reviewed, 2018)
      The encoding of time and its binding to events are crucial for episodic memory, but how these processes are carried out in hippocampal–entorhinal circuits is unclear. Here we show in freely foraging rats that temporal ...
    • Integration of grid maps in merged environments 

      Wernle, Tanja; Waaga, Torgeir; Mørreaunet, Maria; Treves, Alessandro; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2018)
      Natural environments are represented by local maps of grid cells and place cells that are stitched together. The manner by which transitions between map fragments are generated is unknown. We recorded grid cells while rats ...
    • Large-scale two-photon calcium imaging in freely moving mice 

      Zong, Weijian; Obenhaus, Horst-Andreas; Skytøen, Emilie; Eneqvist, Hanna; de Jong, Nienke Laura; Vale, Ruben Duque do; Rodrigues Jorge, Marina; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2022)
      We developed a miniaturized two-photon microscope (MINI2P) for fast, high-resolution, multiplane calcium imaging of over 1,000 neurons at a time in freely moving mice. With a microscope weight below 3 g and a highly flexible ...
    • Mechanisms of Six-Fold Symmetry in fMRI BOLD-Signal: An Analysis of a Large Grid Cell Dataset 

      Slettmoen, Torstein (Master thesis, 2020)
      Hippocampusformasjonen si rolle i romleg navigering og som hjernen sitt indre romlege kart har vore annerkjend sidan oppdaginga av stadsceller og gitterceller. Gjennom omfattande forsking, hovudsakleg utført i gnagarar, ...
    • Object-centered neural coding in the entorhinal cortex and hippocampus 

      Andersson, Sebastian (Doctoral theses at NTNU;2023:24, Doctoral thesis, 2022)
    • Observations on the Hippocampal Formation: A study on the anatomy of the dentate-ammonic region in mink, sheep, and domestic pig, and spatial representations in the CA1 and subiculum of rats. 

      Blackstad, Jan Sigurd Beddari (Doctoral theses at NTNU;2022:129, Doctoral thesis, 2022)
      Sammendrag Hippocampusformasjonen omfatter et område i hjernen hos pattedyr som er essensielt for romlig navigasjon og episodiske minner. Overordnet inndeles området i tre subregioner: Gyrus dentatus, cornu ammonis (CA1, ...
    • Optimized Miniature Two-Photon Microscopy for Imaging Neuronal Activity in Freely Moving Mice 

      de Jong, Nienke Laura (Master thesis, 2021)
      Oppfinnelsen av nye avbildningsteknikker har alltid banet vei for påfølgende gjennombrudd i biovitenskapen og det såkalte to-foton mikroskopet er intet unntak. Teknikken muliggjør rask, kalsiumbasert avbildning av ...
    • Parvalbumin and Somatostatin Interneurons Control Different Space-Coding Networks in the Medial Entorhinal Cortex 

      Miao, Chenglin; Cao, Qichen; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2017)
      The medial entorhinal cortex (MEC) contains several discrete classes of GABAergic interneurons, but their specific contributions to spatial pattern formation in this area remain elusive. We employed a pharmacogenetic ...
    • Path integration in place cells of developing rats 

      Bjerknes, Tale Litlere; Dagslott, Nenitha; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2018)
      Place cells in the hippocampus and grid cells in the medial entorhinal cortex rely on self-motion information and path integration for spatially confined firing. Place cells can be observed in young rats as soon as they ...
    • Place cells in the hippocampus: Eleven maps for eleven rooms 

      Alme, Charlotte; Miao, Chenglin; Jezek, Karel; Treves, Alessandro; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2014)
      The contribution of hippocampal circuits to high-capacity episodic memory is often attributed to the large number of orthogonal activity patterns that may be stored in these networks. Evidence for high-capacity storage in ...
    • Place cells, grid cells, and memory 

      Moser, May-Britt; Rowland, David Clayton; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2015)
      The hippocampal system is critical for storage and retrieval of declarative memories, including memories for locations and events that take place at those locations. Spatial memories place high demands on capacity. Memories ...
    • Population codes for space in the medial entorhinal cortex and hippocampus 

      Nagelhus, Anne (Doctoral theses at NTNU;2024:132, Doctoral thesis, 2024)
      Navigation and the ability to orient oneself in the external environment is fundamental for humans and other animals. The hippocampus and the medial entorhinal cortex (MEC) contain cells that are believed to support spatial ...
    • Ready, steady, go! Development of spatial representations in the rat 

      Kruge, Ingvild Ulsaker (Doctoral theses at NTNU;2016:320, Doctoral thesis, 2016)
      In mice and men, the hippocampal region is the central brain network for declarative memory and dynamic representation of location. Hippocampal place cells and entorhinal grid cells use head direction, border and speed ...
    • Representation of geometric borders in the developing rat 

      Bjerknes, Tale Litlere; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2014)
      Local space is represented by a number of functionally specific cell types, including place cells in the hippocampus and grid cells, head direction cells, and border cells in the medial entorhinal cortex (MEC). These cells ...
    • Spatial Representation in the Hippocampal Formation: A History 

      Moser, Edvard Ingjald; Moser, May-Britt; McNaughton, Bruce (Journal article; Peer reviewed, 2017)
      Since the first place cell was recorded and the cognitive-map theory was subsequently formulated, investigation of spatial representation in the hippocampal formation has evolved in stages. Early studies sought to verify ...
    • Stellate cells drive maturation of the entorhinal-hippocampal circuit 

      Donato, Flavio; Jacobsen, R Irene; Moser, May-Britt; Moser, Edvard I (Journal article; Peer reviewed, 2017)
      The neural representation of space relies on a network of entorhinal-hippocampal cell types with firing patterns tuned to different abstract features of the environment. To determine how this network is set up during early ...
    • Task-dependent mixed selectivity in the subiculum 

      Ledergerber Wäfler, Debora; Battistin, Claudia; Blackstad, Jan Sigurd; Gardner, Richard; Witter, Menno; Moser, May-Britt; Roudi, Yasser; Moser, Edvard Ingjald (Peer reviewed; Journal article, 2021)
      CA1 and subiculum (SUB) connect the hippocampus to numerous output regions. Cells in both areas have place-specific firing fields, although they are more dispersed in SUB. Weak responses to head direction and running speed ...
    • The Egocentric Hippocampus 

      Carpenter, Jordan (Master thesis, 2021)
      Navigation relies on the integration of incoming sensory information with a stable schema that can be applied to map the current environment. This integration results in a dynamic map of the animal’s position based on ...
    • Topography of Place Maps along the CA3-to-CA2 Axis of the Hippocampus 

      Lu, Li; Igarashi, Kei M; Witter, Menno; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2015)
      We asked whether the structural heterogeneity of the hippocampal CA3-CA2 axis is reflected in how space is mapped onto place cells in CA3-CA2. Place fields were smaller and sharper in proximal CA3 than in distal CA3 and ...