• The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage 

      Meza, Trine Johansen; Moen, Marivi; Vågbø, Cathrine Broberg; Krokan, Hans Einar; Klungland, Arne; Grini, Paul Eivind; Falnes, Pål (Journal article; Peer reviewed, 2012)
      The Escherichia coli AlkB protein (EcAlkB) is a DNA repair enzyme which reverses methylation damage such as 1-methyladenine (1-meA) and 3-methylcytosine (3-meC). The mammalian AlkB homologues ALKBH2 and ALKBH3 display ...
    • Ythdf2-mediated m6A mRNA clearance modulates neural development in mice 

      Li, Miaomiao; Zhao, Xu; Wang, Wei; Shi, Hailing; Pan, Qingfei; Lu, Zhike; Perez, Sonia Peña; Suganthan, Rajikala; He, Chuan; Bjørås, Magnar; Klungland, Arne (Journal article; Peer reviewed, 2018)
      Background N 6 -methyladenosine (m6A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 ...