• Pregnancy outcomes according to the definition of gestational diabetes 

      Koivunen, Sanna; Viljakainen, Matti; Männistö, Tuija; Gissler, Mika; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2020)
      Objective To assess the frequency and perinatal outcomes of gestational diabetes mellitus (GDM) defined by the criteria according to the International Association of Diabetes in Pregnancy Study Group (IADPSG) and the ...
    • The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network 

      Selenius, Jannica S.; Silveira, Patricia P.; Salonen, Minna K; Kautiainen, Hannu; von Bonsdorff, Mikaela; Kajantie, Eero Olavi; Lahti, Jari; Eriksson, Johan G.; Wasenius, N. S. (Peer reviewed; Journal article, 2021)
      To investigate whether expression-based polygenic risk scores for the insulin receptor gene network (ePRS-IRs) modifiy the association between type of depressive symptoms and health-related quality of life (HRQoL). This ...
    • Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies 

      Dieckmann, Linda; Cruceanu, Cristiana; Lahti-Pulkkinen, Marius; Lahti, Jari; Kvist, Tuomas; Laivuori, Hannele; Sammallahti, Sara; Villa, Pia M.; Suomalainen-König, Sanna; Rancourt, Rebecca C.; Plagemann, Andreas; Henrich, Wolfgang; Eriksson, Johan G.; Kajantie, Eero Olavi; Entringer, Sonja; Braun, Thorsten; Räikkönen, Katri; Binder, Elisabeth B.; Czamara, Darina (Peer reviewed; Journal article, 2022)
      The placenta is a central organ during early development, influencing trajectories of health and disease. DNA methylation (DNAm) studies of human placenta improve our understanding of how its function relates to disease ...
    • Serum ceramides in early pregnancy as predictors of gestational diabetes 

      Mustaniemi, Sanna; Keikkala, Elina; Kajantie, Eero Olavi; Nurhonen, Markku; Jylhä, Antti; Morin-Papunen, Laure; Öhman, Hanna; Männistö, Tuija; Laivuori, Hannele; Eriksson, Johan G.; Laaksonen, Reijo; Vääräsmäki, Marja; Kaaja, Risto; Gissler, Mika; Pouta, Anneli (Peer reviewed; Journal article, 2023)
      Ceramides contribute to the development of type 2 diabetes but it is uncertain whether they predict gestational diabetes (GDM). In this multicentre case–control study including 1040 women with GDM and 958 non-diabetic ...
    • The utilization of specialized healthcare services among frail older adults in the Helsinki Birth Cohort Study 

      Ikonen, Jenni N.; Eriksson, Johan G.; Salonen, Minna K.; Kajantie, Eero Olavi; Arponen, Otso; Haapanen, Markus J. (Peer reviewed; Journal article, 2021)
      Background The association between frailty and specialized healthcare utilization is not well studied. We, therefore, examined the utilization of specialized healthcare services among frail Finnish older adults. Methods A ...
    • Vitamin D and cognitive function: A Mendelian randomisation study 

      Maddock, Jane; Zhou, Ang; Cavadino, Alana; Kuźma, Elżbieta; Bao, Yanchun; Smart, Melissa C.; Saum, Kai-Uwe; Schöttker, Ben; Engmann, Jorgen; Kjærgaard, Marie; Karhunen, Ville; Zhan, Yiqiang; Lehtimäki, Terho; Rovio, Suvi P.; Byberg, Liisa; Lahti, Jari; Marques-Vidal, Pedro; Sen, Abhijit; Perna, Laura; Schirmer, Henrik; Singh-Manoux, Archana; Auvinen, Juha; Hutri-Kähönen, Nina; Kähönen, Mika; Kilander, Lena; Räikkönen, Katri; Melhus, Håkan; Ingelsson, Erik; Guessous, Idris; Petrovic, Katja E.; Schmidt, Helena; Schmidt, Reinhold; Vollenweider, Peter; Lind, Lars; Eriksson, Johan G.; Michaëlsson, Karl; Raitakari, Olli T; Hägg, Sara; Pedersen, Nancy L.; Herzig, Karl-Heinz; Järvelin, Marjo-Riitta; Veijola, Juha; Kivimäki, Mika; Jorde, Rolf; Brenner, Hermann; Kumari, Meena; Power, Chris; Llewellyn, David J.; Hyppönen, Elina (Journal article; Peer reviewed, 2017)
      The causal nature of the association between hypovitaminosis D and poor cognitive function in mid- to later-life is uncertain. Using a Mendelian randomisation(MR) approach, we examined the causal relationship between 25(OH)D ...