Blar i NTNU Open på forfatter "Dale, Ola"
-
Quantification of doxorubicin in mouse serum and tumor tissue by liquid chromatography tandem mass spectrometry: An application in an in vivo study with murine prostate cancer xenograft tumor and ultrasound-sensitive liposomal doxorubicin
Shrestha, Rinu (Master thesis, 2013)Non-specificity and systemic toxicity are major challenges with cancer chemotherapy. This situation is further complicated by abnormality of tumor microenvironment that presents potential barriers to drug delivery. These ... -
Take-home naloxone for the emergency interim management of opioid overdose: The public health application of an emergency medicine
Strang, John; McDonald, Rebecca; Campbell, Gabrielle; Degenhardt, Louisa; Nielsen, Suzanne; Ritter, Alison; Dale, Ola (Peer reviewed; Journal article, 2019)Naloxone is a well-established essential medicine for the treatment of life-threatening heroin/opioid overdose in emergency medicine. Over two decades, the concept of ‘take-home naloxone’ has evolved, comprising pre-provision ... -
The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses
Skorpen, Frank; von Hofacker, Sebastian; Bjørngaard, Mads; Skogholt, Anne Heidi; Dale, Ola; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2016)BACKGROUND: Genetic variability contributes to variable clinical response to opioids. This study emerged from the observation of three Norwegian patients who showed no or extraordinary poor response to very high doses of ...