Blar i NTNU Open på forfatter "Wisløff, Ulrik"
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5 Years of Exercise Intervention Did Not Benefit Cognition Compared to the Physical Activity Guidelines in Older Adults, but Higher Cardiorespiratory Fitness Did. A Generation 100 Substudy
Sokołowski, Daniel; Hansen, Tor Ivar; Rise, Henning Hoel; Reitlo, Line Skarsem; Wisløff, Ulrik; Stensvold, Dorthe; Håberg, Asta (Peer reviewed; Journal article, 2021)Background: Aerobic exercise is proposed to attenuate cognitive decline in aging. We investigated the effect of different aerobic exercise interventions and cardiorespiratory fitness (CRF) upon cognition throughout a 5-year ... -
A multi-center comparison of vO2peak trainability between interval training and moderate intensity continuous training
Williams, Camilla J.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Voisin, Sarah; Li, Zhixiu; Harvey, Nicholas; Croci, Ilaria; Taylor, Jenna L; Gajanand, Trishan; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Pattyn, Nele; Howden, Erin J.; Keating, Shelley E.; Bye, Anja; Stensvold, Dorthe; Wisløff, Ulrik; Papadimitriou, Ioannis; Yan, Xu; Bishop, David J.; Eynon, Nir; Coombes, Jeff S. (Journal article; Peer reviewed, 2019)There is heterogeneity in the observed VO2peak response to similar exercise training, and different exercise approaches produce variable degrees of exercise response (trainability). The aim of this study was to combine ... -
A Prospective Population Study of Resting Heart Rate and Peak Oxygen Uptake (the HUNT Study, Norway)
Nauman, Javaid; Aspenes, Stian Thoresen; Nilsen, Tom Ivar Lund; Vatten, Lars Johan; Wisløff, Ulrik (Journal article; Peer reviewed, 2012)Objectives: We assessed the prospective association of resting heart rate (RHR) at baseline with peak oxygen uptake (VO2peak) 23 years later, and evaluated whether physical activity (PA) could modify this association. ... -
A randomised controlled study of the long-term effects of exercise training on mortality in elderly people: Study protocol for the generation 100 study
Stensvold, Dorthe; Viken, Hallgeir; Rognmo, Øivind; Skogvoll, Eirik; Steinshamn, Sigurd Loe; Vatten, Lars Johan; Coombes, Jeff S; Anderssen, Sigmund Alfred; Magnussen, Jon; Ingebrigtsen, Jan Erik; Singh, Maria A Fiatarone; Langhammer, Arnulf; Støylen, Asbjørn; Helbostad, Jorunn L.; Wisløff, Ulrik (Journal article; Peer reviewed, 2015)Introduction: Epidemiological studies suggest that exercise has a tremendous preventative effect on morbidity and premature death, but these findings need to be confirmed by randomised trials. Generation 100 is a randomised, ... -
A small molecule activator of AKT does not reduce ischemic injury of the rat heart
Moreira, Jose Bianco Nascimento; Wohlwend, Martin; Alves, Marcia Netto Magalhaes; Wisløff, Ulrik; Bye, Anja (Journal article; Peer reviewed, 2015)Background Activation of protein kinase AKT is required for cardioprotection by ischemic preconditioning, and transgenic overexpression of AKT protects the heart against ischemia. However, it is unknown whether acute ... -
Absolute and relative accelerometer thresholds for determining the association between physical activity and metabolic syndrome in the older adults: The Generation-100 study
Zisko, Nina; Nauman, Javaid; Bucher Sandbakk, Silvana; Aspvik, Nils Petter; Salvesen, Øyvind; Carlsen, Trude; Viken, Hallgeir; Ingebrigtsen, Jan Erik; Wisløff, Ulrik; Stensvold, Dorthe (Journal article; Peer reviewed, 2017)Background When assessing population adherence to physical activity (PA) recommendation using accelerometers, absolute intensity threshold definition is applied despite having limited validity in those with low cardiorespiratory ... -
Accuracy of heart rate watches: Implications for weight management
Wallen, Matthew P; Gomersall, Sjaan R; Keating, Shelley E; Wisløff, Ulrik; Coombes, Jeff S (Peer reviewed; Journal article, 2016)Background Wrist-worn monitors claim to provide accurate measures of heart rate and energy expenditure. People wishing to lose weight use these devices to monitor energy balance, however the accuracy of these devices ... -
Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial
Smenes, Benedikte; Bækkerud, Fredrik Hjulstad; Slagsvold, Katrine Hordnes; Hassel, Erlend; Wohlwend, Martin; Pinho, Maria; Høydal, Morten; Wisløff, Ulrik; Rognmo, Øivind; Wahba, Alexander (Journal article; Peer reviewed, 2018)OBJECTIVES During open-heart surgery, the myocardium experiences ischaemia–reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia–reperfusion injury ... -
Aerobic Capacity and Cardiorespiratory Reference Data in Healthy Adults: Cross-sectional descriptions, associations and predictive equations for key physiological variables
Loe, Henrik (Doctoral theses at NTNU;2016:293, Doctoral thesis, 2016)SAMMENDRAG Hovedmålene i denne avhandlingen var å etablere et referanse materiale på fysiologiske nøkkelvariabler for friske voksne, og å utvikle modeller for å predikere peak oksygen opptak (VO2peak). Dette er det største ... -
Aerobic capacity reference data in 3816 healthy men and women 20-90 years
Loe, Henrik; Rognmo, Øivind; Saltin, Bengt; Wisløff, Ulrik (Journal article; Peer reviewed, 2013)Purpose: To provide a large reference material on aerobic fitness and exercise physiology data in a healthy population of Norwegian men and women aged 20–90 years. Methods: Maximal and sub maximal levels of VO2, heart ... -
Aerobic exercise training rescues cardiac protein quality control and blunts endoplasmic reticulum stress in heart failure rats
Bozi, Luiz H.M.; Jannig, Paulo R; Rolim, Natale Pinheiro Lage; Voltarelli, Vanessa; Dourado, Paulo MM; Wisløff, Ulrik; Brum, Patricia C. (Peer reviewed; Journal article, 2016)Cardiac endoplasmic reticulum (ER) stress through accumulation of misfolded proteins plays a pivotal role in cardiovascular diseases. In an attempt to reestablish ER homoeostasis, the unfolded protein response (UPR) is ... -
Aerobic interval training partly reverse contractile dysfunction and impaired Ca2+ handling in atrial myocytes from rats with post infarction heart failure
Johnsen, Anne Berit; Høydal, Morten Andre; Røsbjørgen, Ragnhild; Stølen, Tomas; Wisløff, Ulrik (Journal article; Peer reviewed, 2013)Background: There is limited knowledge about atrial myocyte Ca2+ handling in the failing hearts. The aim of this study was to examine atrial myocyte contractile function and Ca2+ handling in rats with post-infarction heart ... -
Age-related change in peak oxygen uptake and change of cardiovascular risk factors. The HUNT Study
Letnes, Jon Magne; Dalen, Håvard; Aspenes, Stian Thoresen; Salvesen, Øyvind; Wisløff, Ulrik; Nes, Bjarne (Peer reviewed; Journal article, 2020)Background Large longitudinal studies on change in directly measured peak oxygen uptake (VO2peak) is lacking, and its significance for change of cardiovascular risk factors is uncertain. We aimed to assess ten-year ... -
Age-related decline in peak oxygen uptake: Cross-sectional vs. longitudinal findings. A review
Letnes, Jon Magne; Nes, Bjarne Martens; Wisløff, Ulrik (Peer reviewed; Journal article, 2023)Cardiorespiratory fitness is established as an important prognostic factor for cardiovascular and general health. In clinical settings cardiorespiratory fitness is often measured by cardiopulmonary exercise testing determining ... -
Are Older Adults Physically Active Enough - A Matter of Assessment Method? The Generation 100 Study
Aspvik, Nils Petter; Viken, Hallgeir; Zisko, Nina; Ingebrigtsen, Jan Erik; Wisløff, Ulrik; Stensvold, Dorthe (Journal article; Peer reviewed, 2016)Introduction: Physical activity (PA) is beneficial for general health. As a result, adults around the world are recommended to undertake regular PA of either absolute or relative intensity. Traditionally, adherence to PA ... -
Association between Personal Activity Intelligence (PAI) and body weight in a population free from cardiovascular disease - The HUNT study
Kieffer, Sophie Kvalheim; Nauman, Javaid; Syverud, Kari; Selboskar, Hege; Lydersen, Stian; Ekelund, Ulf; Wisløff, Ulrik (Peer reviewed; Journal article, 2021)Background: Personal Activity Intelligence (PAI) is a new metric for physical activity tracking, and is associated with reduced risk of all-cause and cardiovascular mortality. We prospectively investigated whether PAI is ... -
Association between pulmonary function and peak oxygen uptake in elderly: the Generation 100 study
Hassel, Erlend; Stensvold, Dorthe; Halvorsen, Thomas; Wisløff, Ulrik; Langhammer, Arnulf; Steinshamn, Sigurd Loe (Peer reviewed; Journal article, 2015)Background Although reduced function of the respiratory system limits peak oxygen uptake in diseases affecting the lungs or airways, the healthy respiratory system is thought to have a spare capacity for oxygen transport ... -
The association of change in peak oxygen uptake with use of psychotropics in community-dwelling older adults - The Generation 100 study
Carlsen, Trude; Stensvold, Dorthe; Wisløff, Ulrik; Ernstsen, Linda; Halvorsen, Thomas (Peer reviewed; Journal article, 2022)Background The use of psychotropics is high among the older population and may have detrimental effects on their physical and mental health. Cardiorespiratory fitness (CRF) is a strong and modifiable measure of health ... -
Atherogenic lipidomics profile in healthy individuals with low cardiorespiratory fitness: The HUNT3 fitness study
Nodeland, Markus; Klevjer, Marie; Sæther, Julie Caroline; Giskeødegård, Guro F.; Bathen, Tone Frost; Wisløff, Ulrik; Bye, Anja (Journal article; Peer reviewed, 2022) -
Atrial fibrillation and exercise
Malmo, Vegard (Doctoral theses at NTNU;2019:60, Doctoral thesis, 2019)Atrial fibrillation (AF) is the most common persistent arrhythmia, with a prevalence of 2-3% in the adult population and is associated with an increased morbidity and mortality. This is caused by an increased risk of stroke ...