Blar i NTNU Open på tidsskrift "Frontiers in Bioengineering and Biotechnology"
Viser treff 1-16 av 16
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Detection of environmental nanoplastics via surface-enhanced Raman spectroscopy using high-density, ring-shaped nanogap arrays
(Peer reviewed; Journal article, 2023)Micro- and nano-plastics (MNPs) are global contaminants of growing concern to the ecosystem and human health. In-the-field detection and identification of environmental micro- and nano-plastics (e-MNPs) is critical for ... -
Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus
(Journal article; Peer reviewed, 2021)The use of methanol as carbon source for biotechnological processes has recently attracted great interest due to its relatively low price, high abundance, high purity, and the fact that it is a non-food raw material. In ... -
From Brown Seaweed to a Sustainable Microbial Feedstock for the Production of Riboflavin
(Peer reviewed; Journal article, 2022)The increasing global demand for food and energy production encourages the development of new production strategies focused on sustainability. Often, microbial bioprocesses rely on food or feed competitive feedstocks; ... -
HyperXpress: Rapid Single Vessel DNA Assembly and Protein Production in Microliterscale
(Journal article; Peer reviewed, 2022) -
Identification and Cross-Characterisation of Artificial Promoters and 5′ Untranslated Regions in Vibrio natriegens
(Peer reviewed; Journal article, 2022)Vibrio natriegens has recently gained attention as a novel fast-growing bacterium in synthetic biology applications. Currently, a limited set of genetic elements optimised for Escherichia coli are used in V. natriegens due ... -
Identification of Regulatory Genes and Metabolic Processes Important for Alginate Biosynthesis in Azotobacter vinelandii by Screening of a Transposon Insertion Mutant Library
(Journal article; Peer reviewed, 2020)Azotobacter vinelandii produces the biopolymer alginate, which has a wide range of industrial and pharmaceutical applications. A random transposon insertion mutant library was constructed from A. vinelandii ATCC12518Tc in ... -
The impact of serum-free culture on HEK293 cells: From the establishment of suspension and adherent serum-free adaptation cultures to the investigation of growth and metabolic profiles
(Peer reviewed; Journal article, 2022)Serum-free cultures are preferred for application in clinical cell therapy and facilitate the purification processes of bioproducts, such as vaccines and recombinant proteins. It can replace traditional cell culture - ... -
Integrated flow chamber device for live cell microscopy
(Journal article; Peer reviewed, 2019)In vitro quantification of the effect of mechanical loads on cells by live microscopy requires precise control of load and culture environment. Corresponding systems are often bulky, their setup and maintenance are time ... -
mCherry contains a fluorescent protein isoform that interferes with its reporter function
(Peer reviewed; Journal article, 2022)Fluorescent proteins are essential reporters in cell and molecular biology. Here, we found that red-fluorescent proteins possess an alternative translation initiation site that produces a short functional protein isoform ... -
A multi-sensor wearable system for the assessment of diseased gait in real-world conditions
(Peer reviewed; Journal article, 2023)Introduction: Accurately assessing people’s gait, especially in real-world conditions and in case of impaired mobility, is still a challenge due to intrinsic and extrinsic factors resulting in gait complexity. To improve ... -
Photosensitized and Photothermal Stimulation of Cellular Membranes by Organic Thin Films and Nanoparticles
(Peer reviewed; Journal article, 2022)Conjugated polymers are increasingly exploited for biomedical applications. In this work, we explored the optical characteristics of conjugated polymers of variable chemical structures at multiple levels relevant to ... -
Poro-viscoelastic material parameter identification of brain tissue-mimicking hydrogels
(Peer reviewed; Journal article, 2023)Understanding and characterizing the mechanical and structural properties of brain tissue is essential for developing and calibrating reliable material models. Based on the Theory of Porous Media, a novel nonlinear ... -
Region- and layer-specific investigations of the human menisci using SHG imaging and biaxial testing
(Peer reviewed; Journal article, 2023)In this paper, we examine the region- and layer-specific collagen fiber morphology via second harmonic generation (SHG) in combination with planar biaxial tension testing to suggest a structure-based constitutive model for ... -
Spheroid Coculture of Human Gingiva-Derived Progenitor Cells With Endothelial Cells in Modified Platelet Lysate Hydrogels
(Peer reviewed; Journal article, 2021)Cell coculture strategies can promote angiogenesis within tissue engineering constructs. This study aimed to test the angiogenic potential of human umbilical vein endothelial cells (HUVEC) cocultured with gingiva-derived ... -
Sulfated alginate reduces pericapsular fibrotic overgrowth on encapsulated cGMP-compliant hPSC-hepatocytes in mice
(Peer reviewed; Journal article, 2022)Intra-peritoneal placement of alginate encapsulated human induced pluripotent stem cell-derived hepatocytes (hPSC-Heps) represents a potential new bridging therapy for acute liver failure. One of the rate-limiting steps ... -
Vasodilatory effects of glucagon: A possible new approach to enhanced subcutaneous insulin absorption in artificial pancreas devices
(Peer reviewed; Journal article, 2022)Patients with diabetes mellitus type 1 depend on exogenous insulin to keep their blood glucose concentrations within the desired range. Subcutaneous bihormonal artificial pancreas devices that can measure glucose concentrations ...