Blar i NTNU Open på forfatter "Nykter, Matti"
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CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity
Filppu, Paulinna; Ramanathan, Jayendrakishore; Granberg, Kirsi J.; Gucciardo, Erika; Haapasalo, Hannu; Lehti, Kaisa; Nykter, Matti; Le Joncour, Vadim; Laakkonen, Pirjo (Peer reviewed; Journal article, 2021)Glioma stem cells (GSCs) drive propagation and therapeutic resistance of glioblastomas, the most aggressive diffuse brain tumors. However, the molecular mechanisms that maintain the stemness and promote therapy resistance ... -
Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems
Hamis, Sara; Somervuo, Panu; Ågren, J Arvid; Tadele, Dagim Shiferaw; Kesseli, Juha; Scott, Jacob G.; Nykter, Matti; Gerlee, Philip; Finkelshtein, Dmitri; Ovaskainen, Otso Tapio (Peer reviewed; Journal article, 2023)Theoretical and applied cancer studies that use individual-based models (IBMs) have been limited by the lack of a mathematical formulation that enables rigorous analysis of these models. However, spatial cumulant models ...