Blar i NTNU Open på forfatter "Mæhlum, Astfrid Helene Morka"
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Central carbon metabolite profiling reveals vector-associated differences in the recombinant protein production host Escherichia coli BL21
Garcia Calvo, Laura; Rane, Divyata Vilas; Everson, Nikalet; Humlebrekk, Sigurd Tømmerberg; Mathiassen, Lise Femanger; Mæhlum, Astfrid Helene Morka; Malmo, Jostein; Bruheim, Per (Peer reviewed; Journal article, 2023)The Gram-negative bacterium Escherichia coli is the most widely used host for recombinant protein production, both as an industrial expression platform and as a model system at laboratory scale. The recombinant protein ... -
Growth Characterization and Mass Spectrometric Metabolic Profiling of Escherichia coli During Recombinant Protein Production
Mæhlum, Astfrid Helene Morka (Master thesis, 2021)Sammendrag Escherichia coli er en mye brukt vertsorganisme for rekombinant proteinproduksjon (RPP). Likevel presenterer denne bakterien fremdeles ulemper som hemmer proteinutbyttet. Utvikling og optimalisering av rekombinante ...