Blar i NTNU Open på forfatter "Li, Keshuai"
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An oil containing EPA and DHA from transgenic Camelina sativa to replace marine fish oil in feeds for Atlantic salmon (Salmo salar L.): Effects on intestinal transcriptome, histology, tissue fatty acid profiles and plasma biochemistry
Betancor, Monica B; Li, Keshuai; Sprague, Matthew; Bardal, Tora; Sayanova, Olga; Usher, Sarah; Han, Lihua; Måsøval, Kjell; Torrissen, Ole; Napier, Johnathan; Tocher, Douglas R.; Olsen, Rolf Erik (Journal article; Peer reviewed, 2017)New de novo sources of omega 3 (n-3) long chain polyunsaturated fatty acids (LC-PUFA) are required as alternatives to fish oil in aquafeeds in order to maintain adequate levels of the beneficial fatty acids, eicosapentaenoic ... -
Comparative transcriptomics reveals domestication‐associated features of Atlantic salmon lipid metabolism
Jin, Yang; Olsen, Rolf Erik; Harvey, Thomas Nelson; Østensen, Mari-Ann; Li, Keshuai; Santi, Nina; Vadstein, Olav; Bones, Atle M.; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Peer reviewed; Journal article, 2020)Domestication of animals imposes strong targeted selection for desired traits but can also result in unintended selection due to new domestic environments. Atlantic salmon was domesticated in the 1970s and has subsequently ... -
CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes
Winge, Per; Datsomor, Alex; Olsen, Rolf Erik; Jin, Yang; Vik, Jon Olav; Edvardsen, Rolf; Grammes, Fabian; Wargelius, Anna; Li, Keshuai (Journal article; Peer reviewed, 2019)Atlantic salmon can synthesize polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (20:5n-3), arachidonic acid (20:4n-6) and docosahexaenoic acid (22:6n-3) via activities of very long chain fatty acyl elongases ... -
Hydrolysis activity of pyloric cecal enterocytes of brown trout (Salmo trutta) toward monoacylglycerol and lysophosphatidylcholine
Li, Keshuai; Egelandsdal, Bjørg; Olsen, Rolf Erik (Journal article; Peer reviewed, 2018)Some lipid digestion pathways in fish deviate from those in mammals, and many differences may also be species dependent. This report describes a pathway for monoacylglycerol (MAG) and lysophospholipid absorption by intestinal ... -
Influence of nitrogen limitation on lipid accumulation and EPA and DHA content in four marine microalgae for possible use in aquafeed
Wang, Xinxin; Fosse, Hilde Karoline; Li, Keshuai; Chauton, Matilde Skogen; Vadstein, Olav; Reitan, Kjell Inge (Journal article; Peer reviewed, 2019)Microalgae are regarded as a promising alternative that can replace fishmeal and fish oil in aquaculture. Under N-limitation, many microalgae species change their carbon storage patterns in favor of neutral lipids (NLs) ... -
Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar)
Betancor, Mónica B.; Li, Keshuai; Bucerzan, Valentin S.; Sprague, Matthew; Sayanova, Olga; Usher, Sarah; Han, Lihua; Norambuena, Fernando; Torrissen, Ole; Napier, Johnathan A.; Tocher, Douglas R.; Olsen, Rolf Erik (Journal article; Peer reviewed, 2018)Facing a bottleneck in the growth of aquaculture, and a gap in the supply and demand of the highly beneficial n-3 long-chain PUFA (LC-PUFA), sustainable alternatives to traditional marine-based feeds are required. Therefore, ... -
Pathways of Lipid Metabolism in Marine Algae, Co-Expression Network, Bottlenecks and Candidate Genes for Enhanced Production of EPA and DHA in Species of Chromista
Mühlroth, Alice; Li, Keshuai; Røkke, Gunvor; Winge, Per; Olsen, Yngvar; Hohmann-Marriott, Martin Frank; Vadstein, Olav; Bones, Atle M. (Journal article; Peer reviewed, 2013)The importance of n-3 long chain polyunsaturated fatty acids (LC-PUFAs) for human health has received more focus the last decades, and the global consumption of n-3 LC-PUFA has increased. Seafood, the natural n-3 LC-PUFA ... -
Phospholipids in Atlantic cod (Gadus morhua L.) larvae rearing: Incorporation of DHA in live feed and larval phospholipids and the metabolic capabilities of larvae for de novo synthesis
Li, Keshuai (Doctoral thesis at NTNU;2015:257, Doctoral thesis, 2015) -
Rearing water treatment induces microbial selection influencing the microbiota and pathogen associated transcripts of cod (Gadus morhua) larvae.
Vestrum, Ragnhild Inderberg; Attramadal, Kari; Winge, Per; Li, Keshuai; Olsen, Yngvar; Bones, Atle M.; Vadstein, Olav; Bakke, Ingrid (Journal article; Peer reviewed, 2018)We have previously shown that K-selection and microbial stability in the rearing water increases survival and growth of Atlantic cod (Gadus morhua) larvae, and that recirculating aquaculture systems (RAS) are compatible ... -
Transcriptional regulation of lipid metabolism when salmon fry switches from endogenous to exogenous feeding
Jin, Yang; Olsen, Rolf Erik; Østensen, Mari-Ann; Gillard, Gareth Benjamin; Li, Keshuai; Harvey, Thomas Nelson; Santi, Nina; Vadstein, Olav; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)The onset of first feeding is a critical period for Atlantic salmon (Salmo salar). The fish goes through a dramatic transition, from using the yolk sac as an energy and nutrient resource to rely on exogenous food. However, ...