Blar i NTNU Open på forfatter "Kjesbu, Joachim Sebastian"
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Alginate and tunicate nanocellulose composite microbeads – Preparation, characterization and cell encapsulation
Kjesbu, Joachim Sebastian; Zaitseva-Zotova, Daria; Sämfors, Sanna; Gatenholm, Paul; Troedsson, Christofer; Thompson, Eric Malcolm; Strand, Berit Løkensgard (Peer reviewed; Journal article, 2022)Alginate has been used for decades for cell encapsulation. Cellulose nanofibrils (CNF) from tunicates are desirable in biomedicine due to high molecular weight, purity, crystallinity, and sustainable production. We prepared ... -
Alginate Beads for the Treatment of Diabetes - Development of Larger Beads with Various Compartments
Kjesbu, Joachim Sebastian (Master thesis, 2016)Some diseases lead to the loss of specific types of cells and their associated products, notably type 1 diabetes, an autoimmune disease which causes the loss of the insulin producing β-cells native to the pancreas. Cell ... -
Alginate-polycation capsules as microcarriers for cell culture - Preparation and characterization
Solheim, Ingeborg Elisabeth (Master thesis, 2019)Celler kan miste sin form og funksjon når de blir kultivert på 2D-overflater, som er den nåværende standarden. Derfor kreves bedre kultiveringsmetoder for å få et mer nøyaktig bilde av cellenes oppførsel og interaksjoner. ... -
Hydrogel beads from marine polysaccharides: Investigation of bead formulations for use in cell encapsulation
Kjesbu, Joachim Sebastian (Doctoral theses at NTNU;2022:287, Doctoral thesis, 2022)Sykdommer som type 1 diabetes og akutt leversvikt kan behandles med transplantasjon. Et mindre omfattende inngrep kan gjøres ved bruk av isolerte celler fremfor hele organer. Likevel krever transplantasjon immundempende ... -
Serum-free alginate-C2C12 cells microcapsule culture as an alternative source of animal protein
Scheffold, Jana; Bruheim, Per; Kjesbu, Joachim Sebastian; Jang, Mi (Peer reviewed; Journal article, 2023)Due to the climate change crisis, and environmental impacts of the traditional meat sector, the production of artificial animal protein based on in vitro cell culture technology is proposed as an alternative. Furthermore, ... -
Sulfated alginate reduces pericapsular fibrotic overgrowth on encapsulated cGMP-compliant hPSC-hepatocytes in mice
Syanda, Adam M.; Kringstad, Vera I.; Blackford, Samuel J.I.; Kjesbu, Joachim Sebastian; Ng, Soon Seng; Ma, Liang; Xiao, Fang; Coron, Abba Elizabeth; Rokstad, Anne Mari A.; Modi, Sunil; Rashid, S. Tamir; Strand, Berit Løkensgard (Peer reviewed; Journal article, 2022)Intra-peritoneal placement of alginate encapsulated human induced pluripotent stem cell-derived hepatocytes (hPSC-Heps) represents a potential new bridging therapy for acute liver failure. One of the rate-limiting steps ...