Blar i NTNU Open på forfatter "Howe, Laura D."
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Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study
Hughes, Amanda M.; Sanderson, Eleanor; Morris, Tim; Ayorech, Ziada; Tesli, Martin Steen; Ask, Helga; Reichborn-Kjennerud, Ted; Andreassen, Ole; Magnus, Per Minor; Helgeland, Øyvind; Johansson, Stefan; Njølstad, Pål Rasmus; Davey Smith, George; Havdahl, Alexandra Karoline Saasen; Howe, Laura D.; Davies, Neil Martin (Peer reviewed; Journal article, 2022)Background: Higher BMI in childhood is associated with emotional and behavioural problems, but these associations may not be causal. Results of previous genetic studies imply causal effects but may reflect influence of ... -
The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization
Korologou-Linden, Roxanna; Bhatta, Laxmi; Brumpton, Ben Michael; Howe, Laura D.; Millard, Louise A. C.; Kolaric, Katarina; Ben-Shlomo, Yoav; Williams, Dylan M.; Smith, George Davey; Anderson, Emma L.; Stergiakouli, Evie; Davies, Neil Martin (Peer reviewed; Journal article, 2022)Alzheimer’s disease (AD) has no proven causal and modifiable risk factors, or effective interventions. We report a phenome-wide association study (PheWAS) of genetic liability for AD in 334,968 participants of the UK Biobank ... -
Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study
Hughes, Amanda; Wade, Kaitlin H; Dickson, Matt; Rice, Frances; Davies, Alisha R.; Davies, Neil Martin; Howe, Laura D. (Peer reviewed; Journal article, 2021)Good health is positively related to children’s educational outcomes, but relationships may not be causal. Demonstrating a causal influence would strongly support childhood and adolescent health as important for education ... -
Effects of depression on employment and social outcomes: A Mendelian randomisation study
Campbell, Desmond; Green, Michael James; Davies, Neil Martin; Demou, Evangelia; Howe, Laura D.; Harrison, Sean; Smith, Daniel J.; Howard, David M.; McIntosh, Andrew M.; Munafò, Marcus; Katikireddi, Srinivasa Vittal (Journal article; Peer reviewed, 2022) -
Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank
Harrison, Sean; Davies, Neil Martin; Howe, Laura D.; Hughes, Amanda (Peer reviewed; Journal article, 2021)Men with more advantaged socioeconomic position (SEP) have been observed to have higher levels of testosterone. It is unclear whether these associations arise because testosterone has a causal impact on SEP. In 306,248 ...