Blar i NTNU Open på forfatter "Herlofson, Bente Brokstad"
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Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts
Kruger, Tormod Bjartveit; Herlofson, Bente Brokstad; Lian, Aina-Mari; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2021)Objective: Due to gastrointestinal side effects of oral bisphosphonates (BPs), proton pump inhibitors (PPIs) are often prescribed. PPIs may enhance the risk of osteonecrosis of the jaw, a rare side effect of BPs. Therefore, ... -
Risk assessment of "other substances" – Coenzyme Q10. Opinion of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics of the Norwegian Scientific Committee for Food Safety
Herlofson, Bente Brokstad; Mathisen, Gro Haarklou; Bruzell, Ellen Merete; Granum, Berit; Hetland, Ragna Bogen; Husøy, Trine; Rohloff, Jens; Wicklund, Trude; Steffensen, Inger-Lise (VKM Report;, Research report, 2015)The Norwegian Scientific Committee for Food Safety (VKM) has, at the request of the Norwegian Food Safety Authority, assessed the risk of intake of 100 mg/day of coenzyme Q10 in food supplements. For the risk characterization, ... -
Risk assessments of aspartame, acesulfame K, sucralose and benzoic acid from soft drinks, “saft”, nectar and flavoured water. Opinion of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics of the Norwegian Scientific Committee for Food Safety
Steffensen, Inger-Lise; Alexander, Jan; Binderup, Mona-Lise; Bruzell, Ellen Merete; Dahl, Knut Helkås; Granum, Berit; Herlofson, Bente Brokstad; Hetland, Ragna Bogen; Husøy, Trine; Paulsen, Jan Erik; Rohloff, Jens; Thrane, Vibeke; Wicklund, Trude (VKM Report;, Research report, 2014)The Norwegian Scientific Committee for Food Safety (Vitenskapskomiteen for mattrygghet, VKM), Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics, has at the request of the ... -
Targeting a therapeutically relevant concentration of alendronate for in vitro studies on osteoblasts
Krüger, Tormod Bjartveit; Syversen, Unni; Herlofson, Bente Brokstad; Lian, Aina-Mari; Reseland, Janne Elin (Peer reviewed; Journal article, 2022)Objective Bisphosphonates like alendronate mainly exert their effects on osteoclasts. However, osteoblasts are also affected, but exposed to a much lower concentration in vivo than the osteoclasts. Given that the effects ...