Blar i NTNU Open på forfatter "Espenes, Arild"
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Demyelinating polyneuropathy in goats lacking prion protein
Skedsmo, Fredrik Strebel; Malachin, Giulia; Våge, Dag Inge; Hammervold, Mie Marie; Salvesen, Øyvind; Ersdal, Cecilie; Ranheim, Birgit; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Bruheim, Per; Jäderlund, Karin Hultin; Matiasek, Kaspar; Espenes, Arild; Tranulis, Michael A. (Journal article; Peer reviewed, 2019)Studies in mice with ablation of Prnp, the gene that encodes the cellular prion protein (PrPC), have led to the hypothesis that PrPC is important for peripheral nerve myelin maintenance. Here, we have used a nontransgenic ... -
Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain
Kristiansen, Steinar; Jarmund, Anders Hagen; Hilmo, Jonas Larsen; Mollnes, Tom Eirik; Leth-Olsen, Martin; Nyrnes, Siri Ann; Nilsen, Bent Aksel; Grønli, Renathe Henriksen; Faldaas, Bjørn Ove; Storm, Benjamin Stage; Espenes, Arild; Nielsen, Erik Waage (Journal article; Peer reviewed, 2024)Background: Shaft fractures of the femur are commonly treated with intramedullary nailing, which can release bone marrow emboli into the bloodstream. Emboli can travel to the lungs, impairing gas exchange and causing ... -
Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D
Skedsmo, Fredrik; Espenes, Arild; Tranulis, Michael A.; Matiasek, Kaspar; Gunnes, Gjermund; Bjerkås, Inge; Moe, Lars; Røed, Susan Skogtvedt; Berendt, Mette; Fredholm, Merete; Rohdin, Cecilia; Shelton, G. Diane; Bruheim, Per; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Hermansen, Lene Cecilie; Stigen, Øyvind; Jäderlund, Karin Hultin (Peer reviewed; Journal article, 2021)Mutations in the N-myc downstream-regulated gene 1 (NDRG1) cause degenerative polyneuropathy in ways that are poorly understood. We have investigated Alaskan Malamute dogs with neuropathy caused by a missense mutation in ... -
Stress resilience of spermatozoa and blood mononuclear cells without prion protein
Reiten, Malin Rokseth; Malachin, Giulia; Kommisrud, Elisabeth; Østby, Gunn Charlotte; Waterhouse, Karin Elisabeth; Krogenæs, Anette Kristine; Kusnierczyk, Anna; Bjørås, Magnar; Jalland, Clara Maria Osnes; Nekså, Liv Heidi; Røed, Susan Skogtvedt; Stenseth, Else-Berit; Myromslien, Frøydis Deinboll; Zeremichael, Teklu Tewoldebrhan; Bakkebø, Maren Kolltveit; Espenes, Arild; Tranulis, Michael A. (Journal article; Peer reviewed, 2018)The cellular prion protein PrPC is highly expressed in neurons, but also present in non-neuronal tissues, including the testicles and spermatozoa. Most immune cells and their bone marrow precursors also express PrPC. ...