Browsing NTNU Open by Author "Vujkovic, Marijana"
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Relationship between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses
Malik, Rainer; Georgakis, Marios K.; Vujkovic, Marijana; Damrauer, Scott M.; Elliott, Paul; Karhunen, Ville; Giontella, Alice; Fava, Cristiano; Hellwege, Jacklyn N.; Shuey, Megan M.; Edwards, Todd L.; Rogne, Tormod; Åsvold, Bjørn Olav; Brumpton, Ben Michael; Burgess, Stephen; Dichgans, Martin; Gill, Dipender (Peer reviewed; Journal article, 2021)Observational studies exploring whether there is a nonlinear effect of blood pressure on cardiovascular disease (CVD) risk are hindered by confounding. This limitation can be overcome by leveraging randomly allocated genetic ... -
Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes
Walker, Venexia M.; Vujkovic, Marijana; Carter, Alice R.; Davies, Neil Martin; Udler, Miriam S.; Levin, Michael G.; Davey Smith, George; Voight, Benjamin F.; Gaunt, Tom R.; Damrauer, Scott M. (Peer reviewed; Journal article, 2022)Aims/hypothesis Type 2 diabetes and atherosclerotic CVD share many risk factors. This study aimed to systematically assess a broad range of continuous traits to separate their direct effects on coronary and peripheral ...