Browsing NTNU Open by Author "Styrkarsdottir, Unnur"

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    • An atlas of genetic determinants of forearm fracture 

      Nethander, Maria; Movérare-Skrtic, Sofia; Kämpe, Anders; Coward, Eivind; Reimann, Ene; Grahnemo, Louise; Borbély, Éva; Helyes, Zsuzsanna; Funck-Brentano, Thomas; Cohen-Solal, Martine; Tuukkanen, Juha; Koskela, Antti; Wu, Jianyao; Li, Lei; Lu, Tianyuan; Gabrielsen, Maiken Elvestad; Mägi, Reedik; Hoff, Mari; Lerner, Ulf H.; Henning, Petra; Ullum, Henrik; Erikstrup, Christian; Brunak, Søren; Ostrowski, Sisse Rye; Langhammer, Arnulf; Tuomi, Tiinamaija; Oddsson, Asmundur; Stefansson, Kari; Pettersson-Kymmer, Ulrika; Pedersen, Ole Birger Vesterager; Styrkarsdottir, Unnur; Mäkitie, Outi; Hveem, Kristian; Richards, J. Brent; Ohlsson, Claes (Journal article; Peer reviewed, 2023)
      Osteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive. Forearm fractures are the most common clinically recognized osteoporotic ...

    • MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk 

      Surakka, Ida; Fritsche, Lars; Zhou, Wei; Backman, Joshua; Kosmicki, Jack A.; Lu, Haocheng; Brumpton, Ben Michael; Nielsen, Jonas B.; Gabrielsen, Maiken Elvestad; Skogholt, Anne Heidi; Wolford, Brooke N.; Graham, Sarah E.; Chen, Y. Eugene; Lee, Seunggeun; Kang, Hyun Min; Langhammer, Arnulf; Forsmo, Siri; Åsvold, Bjørn Olav; Styrkarsdottir, Unnur; Holm, Hilma; Gudbjartsson, Daniel F.; Stefansson, Kari; Baras, Aris; Bai, Xiaodong; Balasubramanian, Suganthi; Barnard, Leland; Blumenfeld, Andrew; Cantor, Michael; Coppola, Giovanni; Economides, Aris; Eom, Gisu; Habegger, Lukas; Hahn, Young; Hawes, Alicia; Jones, Marcus B.; Khalid, Shareef; Lotta, Luca A.; Maxwell, Evan K.; Mitnaul, Lyndon J.; Overton, John D.; Reid, Jeffrey G.; Ferreira, Manuel Allen Revez; Salerno, William; Sharma, Deepika; Shuldiner, Alan R.; Staples, Jeffrey C.; Yadav, Ashish; Abecasis, Goncalo R.; Hveem, Kristian; Willer, Cristen J. (Peer reviewed; Journal article, 2020)
      A major challenge in genetic association studies is that most associated variants fall in the non-coding part of the human genome. We searched for variants associated with bone mineral density (BMD) after enriching the ...