Browsing NTNU Open by Author "Raphael, Kalani L."
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Estimated Kidney Tubular Secretion and Kidney, Cardiovascular, and Mortality Outcomes in CKD: The Systolic Blood Pressure Intervention Trial
Ascher, Simon B.; Shlipak, Michael G.; Katz, Ronit; Bullen, Alexander L.; Scherzer, Rebecca; Hallan, Stein; Cheung, Alfred K.; Raphael, Kalani L.; Estrella, Michelle M.; Jotwani, Vasantha K.; Seegmiller, Jesse C.; Ix, Joachim H.; Garimella, Pranav S. (Peer reviewed; Journal article, 2022)Rational & Objective Many drugs, metabolites, and toxins are cleared by the kidneys via tubular secretion. Whether novel endogenous measures of tubular secretion provide information about kidney, cardiovascular, and ... -
Markers of Kidney Tubular Secretion and Risk of Adverse Events in SPRINT Participants with CKD
Bullen, Alexander L.; Ascher, Simon B.; Scherzer, Rebecca; Garimella, Pranav S.; Katz, Ronit; Hallan, Stein; Cheung, Alfred K.; Raphael, Kalani L.; Estrella, Michelle M.; Jotwani, Vasantha K.; Malhotra, Rakesh; Seegmiller, Jesse C.; Shlipak, Michael G.; Ix, Joachim H. (Peer reviewed; Journal article, 2022)Significance Statement SPRINT demonstrated in individuals with hypertension and high cardiovascular disease (CVD) risk that intensive BP lowering was associated with decreased risk of CVD events and all-cause mortality. ...