Browsing NTNU Open by Author "Mintz, Paul J"
Now showing items 1-3 of 3
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A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells
Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G; Nicholls, Joanna P; Haoudi, Abdelali; Gordon, Myrtle YA; Habib, Nagy A (Journal article; Peer reviewed, 2013)Upon functional loss of insulin producing islet β-cells, some patients with diabetes become dependent on life-long insulin supplementation therapy. Bioengineering surrogate insulin producing cells is an alternative replacement ... -
Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells
Voutila, J; Sætrom, Pål; Mintz, Paul J; Sun, Guihua; Alluin, Jessica; Rossi, JJ; Habib, Nagy A.; Kasahara, N. (Journal article; Peer reviewed, 2012)It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells. Using bioinformatics analysis and functional screening, we screened ... -
MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood
Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J; Gaensler, Karin ML; Kasahara, Noriyuki; Nicholls, Joanna P; Jensen, Steen; Haoudi, Abdelali; Emara, Mohamed M; Gordon, Myrtle YA; Habib, Nagy A (Journal article; Peer reviewed, 2012)Exploiting the properties of stem cells by microRNA (miRNA) profiling offers an attractive approach to identify new regulators of stem cell fate. Although numerous miRNA have been screened from hematopoietic stem cells ...