Browsing NTNU Open by Author "Leumann, Christian J."
Now showing items 1-1 of 1
-
3CAPS - A structural AP-site analogue as a tool to investigate DNA base excision repair
Schürmann, David; Scheidegger, Simon P.; Weber, Alain R.; Bjørås, Magnar; Leumann, Christian J.; Schär, Primo (Peer reviewed; Journal article, 2016)Abasic sites (AP-sites) are frequent DNA lesions, arising by spontaneous base hydrolysis or as intermediates of base excision repair (BER). The hemiacetal at the anomeric centre renders them chemically reactive, which ...