Browsing NTNU Open by Author "Ertzgaard, Ingrid"
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Fluorescent Ligands for Detection of Transthyretin Amyloid - Photophysics and Cytotoxicity on Astrocytes
Ertzgaard, Ingrid (Master thesis, 2021)Når proteiner feilfoldes og danner uoppløselige avleiringer får man amyloidfibriller. Sykdommer som forårsakes av disse proteinaggregatene kalles for amyloidose. Når transportproteinet transthyretin (TTR) danner amyloidfibriller ... -
Tau Protein Binding Modes in Alzheimer’s Disease for Cationic Luminescent Ligands
Todarwal, Yogesh; Gustafsson, Camilla; Thi Minh, Nghia Nguyen; Ertzgaard, Ingrid; Klingstedt, Thérese; Ghetti, Bernardino; Vidal, Ruben; König, Carolin; Lindgren, Mikael; Nilsson, K. Peter R.; Linares, Mathieu; Norman, Patrick (Journal article; Peer reviewed, 2021)The bi-thiophene-vinylene-benzothiazole (bTVBT4) ligand developed for Alzheimer’s disease (AD)-specific detection of amyloid tau has been studied by a combination of several theoretical methods and experimental spectroscopies. ...