Browsing NTNU Open by Author "Blomhoff, Heidi Kiil"
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Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
Follin-Arbelet, Virginie; Hofgaard, Peter Olaf; Hauglin, Harald; Naderi, Soheil; Sundan, Anders; Blomhoff, Rune; Bogen, Bjarne; Blomhoff, Heidi Kiil (Journal article; Peer reviewed, 2011)Background Multiple myeloma is an incurable disease requiring the development of effective therapies which can be used clinically. We have elucidated the potential for manipulating the cAMP signaling pathway as a target ... -
The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM
Follin-Arbelet, Virginie; Misund, Kristine; Naderi, Elin Hallan; Ugland, Hege Katrin; Sundan, Anders; Blomhoff, Heidi Kiil (Journal article; Peer reviewed, 2015)We have previously demonstrated that activation of the cyclic adenosine monophosphate (cAMP) pathway kills multiple myeloma (MM) cells both in vitro and in vivo. In the present study we have investigated the potential of ...