Blar i NTNU Open på forfatter "Bergh, Sverre"
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Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers
Jansen, Iris E.; van der Lee, Sven J.; Gomez-Fonseca, Duber; de Rojas, Itziar; Dalmasso, Maria Carolina; Grenier-Boley, Benjamin; Athanasiu, Lavinia; Bahrami, Shahram; Bergh, Sverre; Djurovic, Srdjan; Fladby, Tormod; Jarholm, Jonas Alexander; Knapskog, Anne Brita; Pålhaugen, Lene; Saltvedt, Ingvild; Selbæk, Geir; Selnes, Per; Andreassen, Ole; Shadrin, Alexey; Skoog, Ingmar; Soininen, Hilkka; Tsolaki, Magda; Van Broeckhoven, Christine; Van Dongen, Jasper; van Swieten, John C.; Vandenberghe, Rik; Vidal, Jean-Sébastien; Visser, Pieter J.; Vogelgsang, Jonathan; Waern, Margda; Wagner, Michael; Wiltfang, Jens; Wittens, Mandy M.J.; Zetterberg, Henrik; Zulaica, Miren; van Duijn, Cornelia M.; Bjerke, Maria; Engelborghs, Sebastiaan; Jessen, Frank; Teunissen, Charlotte E.; Pastor, Pau; Hiltunen, Mikko; Ingelsson, Martin; Clarimón, Jordi; Sleegers, Kristel; Ruiz, Agustín; Ramirez, Alfredo; Cruchaga, Carlos; Lambert, Jean-Charles; van der Flier, Wiesje M. (Peer reviewed; Journal article, 2022)Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer’s disease (AD) more directly than clinical diagnosis. Initiated by the European ... -
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Peer reviewed, 2019)Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ... -
Geriatric assessment with management for older patients with cancer receiving radiotherapy. Protocol of a Norwegian cluster-randomised controlled pilot study
Røyset, Inga Marie; Saltvedt, Ingvild; Rostoft, Siri; Grønberg, Bjørn Henning; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Saltyte Benth, Jurate; Bergh, Sverre; Melby, Line; Halsteinli, Vidar; Døhl, Øystein; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2021)About 50% of patients with cancer are expected to need radiotherapy (RT), and the majority of these are older. To improve outcomes for older patients with cancer, geriatric assessment (GA) with management (GAM) is highly ... -
Geriatric assessment with management for older patients with cancer receiving radiotherapy: a cluster-randomised controlled pilot study
Jordhøy, Marit Slaaen; Røyset, Inga Marie; Saltvedt, Ingvild Tina; Grønberg, Bjørn Henning; Halsteinli, Vidar; Døhl, Øystein; Vossius, Corinna Elisabeth; Kirkevold, Øyvind; Bergh, Sverre; Rostoft, Siri; Oldervoll, Line Merethe; Bye, Asta; Melby, Line Kari; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Saltyte Benth, Jurate (Journal article; Peer reviewed, 2024)Background: Geriatric assessment and management (GAM) improve outcomes in older patients with cancer treated with surgery or chemotherapy. It is unclear whether GAM may provide better function and quality of life (QoL), ... -
Insomnia and risk of dementia in a large population-based study with 11-year follow-up: The HUNT study
Selbæk-Tungevåg, Selma; Selbæk, Geir; Strand, Bjørn Heine; Myrstad, Christian; Livingston, Gill; Lydersen, Stian; Bergh, Sverre; Ernstsen, Linda (Peer reviewed; Journal article, 2023)Despite evidence suggesting that insomnia is associated with the risk of dementia and cognitive dysfunction, studies have shown mixed results. Dementia has a long prodromal phase, and studies with long follow-up are required ... -
A longitudinal cohort study on the use of health and care services by older adults living at home with/without dementia before and during the COVID-19 pandemic: the HUNT study
Ibsen, Tanja Louise; Strand, Bjørn Heine; Bergh, Sverre; Livingston, Gill; Lurås, Hilde; Mamelund, Svenn-Erik; Oude Voshaar, Richard; Rokstad, Anne Marie Mork; Thingstad, Pernille; Gerritsen, Debby L.; Selbæk, Geir (Journal article; Peer reviewed, 2024)Background: Older adults and people with dementia were anticipated to be particularly unable to use health and care services during the lockdown period following the COVID-19 pandemic. To better prepare for future pandemics, ... -
Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci
Witoelar, Aree; Rongve, Arvid; Almdahl, Ina Selseth; Ulstein, Ingun; Engvig, Andreas; White, Linda Rosemary; Selbæk, Geir; Stordal, Eystein; Andersen, Fredrik; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut; Hughes, Timothy; Bergh, Sverre; Bråthen, Geir; Bogdanovic, Nenad; Bettella, Francesco; Wang, Yunpeng; Athanasiu, Lavinia; Bahrami, Shahram; Le Hellard, Stephanie; Giddaluru, Sudheer; Dale, Anders M; Sando, Sigrid Botne; Steinberg, Stacy; Stefansson, Hreinn; Snaedal, Jon; Desikan, Rahul S; Stefansson, Kari; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2018)A large fraction of genetic risk factors for Alzheimer’s Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) ... -
Midlife Physical Activity, Psychological Distress, and Dementia Risk: The HUNT Study
Zotcheva, Ekaterina; Bergh, Sverre; Selbæk, Geir; Krokstad, Steinar; Håberg, Asta; Strand, Bjørn Heine; Ernstsen, Linda (Journal article; Peer reviewed, 2018)Background: Physical activity (PA) is associated with a decreased dementia risk, whereas psychological distress (distress) is linked to an increased dementia risk. Objective: We investigated independent and joint ... -
Mobility and cognition at admission to the nursing home – a cross-sectional study
Sverdrup, Karen; Bergh, Sverre; Selbæk, Geir; Røen, Irene Mari; Kirkevold, Øyvind; Tangen, Gro Gujord (Journal article; Peer reviewed, 2018)Background Earlier studies show that the main reasons for admission to long-term nursing home care are cognitive impairment and functional impairments of activities of daily life. However, descriptive evidence of mobility ... -
Modifiable factors affecting older patients' quality of life and physical function during cancer treatment
Kirkhus, Lene; Harneshaug, Magnus; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Bergh, Sverre; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Kirkevold, Øyvind; Borza, Tom; Saltvedt, Ingvild; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)Background Maintaining physical function and quality of life (QoL) are prioritized outcomes among older adults. We aimed to identify potentially modifiable factors affecting older patients' physical function and QoL ... -
Neuropsychiatric Symptoms in Persons with Dementia before and after Admission to Nursing Homes
Mukilvannan, Gardinija; Skånøy, Berit Sofie Jonassen (Master thesis, 2022)Målsetting: Målsettingen med denne studien var å beskrive nevropsykiatriske symptomer (NPS) hos personer med demens før og i løpet av den første måneden etter ankomst til sykehjem. Videre ønsket vi å undersøke faktorer ... -
Neuropsychiatric Symptoms in Persons with Dementia before and after Admission to Nursing Homes
Skånøy, Berit Sofie Jonassen; Mukilvannan, Gardinija (Master thesis, 2022)Målsetting: Målsettingen med denne studien var å beskrive nevropsykiatriske symptomer (NPS) hos personer med demens før og i løpet av den første måneden etter ankomst til sykehjem. Videre ønsket vi å undersøke faktorer ... -
Pain and quality of life in nursing home residents with dementia after admission – a longitudinal study
Helvik, Anne-Sofie; Bergh, Sverre; Saltyte Benth, Jurate; Borza, Tom; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2023)Background Pain in nursing home (NH) residents with dementia is commonly reported and may affect Quality of Life (QoL) negatively. Few longitudinal studies have explored how pain and QoL develop in NH residents with ... -
Pain and quality of life in nursing home residents with dementia after admission – a longitudinal study
Helvik, Anne-Sofie; Bergh, Sverre; Saltyte Benth, Jurate; Borza, Tom; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2023)Pain in nursing home (NH) residents with dementia is commonly reported and may affect Quality of Life (QoL) negatively. Few longitudinal studies have explored how pain and QoL develop in NH residents with dementia starting ... -
Pain in nursing home residents with dementia and its association to quality of life
Helvik, Anne-Sofie; Bergh, Sverre; Šaltytė Benth, Jūratė; Selbæk, Geir; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2021)Abstract Objectives We aimed to describe pain, use of analgesics and quality of life (QoL) in people with dementia admitted to a Norwegian nursing home (NH), and to explore if and how pain was associated with their QoL ... -
Physical performance across the cognitive spectrum and between dementia subtypes in a population-based sample of older adults: The HUNT study
Sverdrup, Karen; Selbæk, Geir; Bergh, Sverre; Strand, Bjørn Heine; Thingstad, Pernille; Skjellegrind, Håvard; Skjerve, Kjerstin Næss; Tangen, Gro Gujord (Journal article; Peer reviewed, 2021)Background: Literature on physical performance in older adults across the cognitive spectrum remains inconclusive, and knowledge on differences between dementia subtypes is lacking. We aim to identify distinct physical-performance ... -
Predictors for Nursing Home Admission and Death among Community-Dwelling People 70 Years and Older Who Receive Domiciliary Care
Wergeland, Jon Normann; Selbæk, Geir; Bergh, Sverre; Söderhamn, Ulrika; Kirkevold, Øyvind (Journal article; Peer reviewed, 2015)Aim: The aim of this study was to analyze which variables predicted nursing home admission (NHA) and death. Methods: 1,001 recipients of domiciliary care were assessed three times in a 3-year period. Through bivariate and ... -
Prevalence and change in alcohol consumption in older adults over time, assessed with self-report and Phosphatidylethanol 16:0/18:1 —The HUNT Study
Tevik, Kjerstin Elisabeth; Skråstad, Ragnhild Bergene; Saltyte Benth, Jurate; Selbæk, Geir; Bergh, Sverre; Eldholm, Rannveig Sakshaug; Krokstad, Steinar; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2024)Background Changes in alcohol consumption may affect older adults’ health. We examined prevalence and changes in the alcohol consumption of older women and men (≥65 years) in Norway over a 24-year period. Methods Data ... -
Prevalence and persistent prescription of analgesic drugs in persons admitted with dementia to a nursing home - A longitudinal study
Helvik, Anne-Sofie; Bergh, Sverre; Kabukcuoglu, Kamile; Saltyte Benth, Jurate; Lichtwarck, Bjørn; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2022)The overall aim was to explore the prevalence and persistent regular prescription of opioids and paracetamol among nursing home (NH) residents with dementia at admission and over time. A total of 996 residents with dementia, ... -
Prevalence and persistent use of analgesic drugs in older adults receiving domiciliary care at baseline - a longitudinal study
Tevik, Kjerstin Elisabeth; Saltyte Benth, Jurate; Aarøen, Marte Kristensen; Lornstad, Marie Turmo; Bergh, Sverre; Helvik, Anne-Sofie (Peer reviewed; Journal article, 2021)Aims To describe the prevalence and persistence of analgesic drug use (opioids and antipyretics [ie, paracetamol and acetylsalicylic acid]) in participants (≥70 years) with and without dementia receiving domiciliary care ...