Blar i NTNU Open på forfatter "Bathen, Tone Frost"
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Oppfølging av pasienter med tilbakefall av prostatakreft etter PSMA-PET
Johansen, Emma Dall (Master thesis, 2024)I denne masteroppgaven presenteres de første oppfølgingsdataene fra den prospektive multisenterstudien 180N PSMA PET and MRI for detection of recurrent prostate cancer after radical treatment. Studien har inkludert ... -
An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue
Høiem, Therese Stork; Andersen, Maria Karoline; Martin-Lorenzo, Marta; Longuespée, Rémi; Claes, Britt S.R.; Nordborg, Anna; Dewez, Frédéric; Balluff, Benjamin; Giampà , Marco; Sharma, Animesh; Hagen, Lars; Heeren, Ron M.A.; Bathen, Tone Frost; Giskeødegård, Guro F.; Krossa, Sebastian; Tessem, May-Britt (Peer reviewed; Journal article, 2022)MALDI MS imaging (MSI) is a powerful analytical tool for spatial peptide detection in heterogeneous tissues. Proper sample preparation is crucial to achieve high quality, reproducible measurements. Here we developed an ... -
Pakkeforløp for prostatakreft: Seleksjon av pasienter - før og underveis i utredning
Jørgensen, Joan Hardbo (Master thesis, 2022)Sammendrag Bakgrunn: Prostatakreft er den vanligste kreftformen blant menn, både globalt og i Norge. Med nye teknikker er det mulig å fange opp kreftformer på et tidlig stadium. Dette gir samtidig risiko for overdiagnostisering, ... -
Pelvic PET/MR attenuation correction in the image space using deep learning
Abrahamsen, Bendik Skarre; Knudtsen, Ingerid Søberg Skjei; Eikenes, Live; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2023) -
Prediction of Clinical Endpoints in Breast Cancer Using NMR Metabolic Profiles
Euceda, Leslie R.; Haukaas, Tonje Husby; Bathen, Tone Frost; Giskeødegård, Guro F. (Chapter, 2018)Metabolic profiles reflect biological conditions as a result of biochemical changes within a living system. It is therefore possible to associate metabolic signatures with clinical endpoints of diseases, such as breast ... -
Prediction of recurrence from metabolites and expression of TOP2A and EZH2 in prostate cancer patients treated with radiotherapy
Hansen, Ailin Falkmo; Høiem, Therese Stork; Selnæs, Kirsten Margrete; Bofin, Anna M.; Størkersen, Øystein; Bertilsson, Helena; Wright, Alan J.; Giskeødegård, Guro F.; Bathen, Tone Frost; Rye, Morten Beck; Tessem, May-Britt (Peer reviewed; Journal article, 2023)Background The dual upregulation of TOP2A and EZH2 gene expression has been proposed as a biomarker for recurrence in prostate cancer patients to be treated with radical prostatectomy. A low tissue level of the metabolite ... -
Preprocessing of NMR metabolomics data
Giskeødegård, Guro F.; Bathen, Tone Frost; Euceda, Leslie R. (Journal article; Peer reviewed, 2015)Metabolomics involves the large scale analysis of metabolites and thus, provides information regarding cellular processes in a biological sample. Independently of the analytical technique used, a vast amount of data is ... -
Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer
Hansen, Ailin Falkmo; Sandsmark, Elise; Rye, Morten Beck; Wright, Alan J; Bertilsson, Helena; Richardsen, Elin; Viset, Trond; Bofin, Anna M.; Angelsen, Anders; Selnæs, Kirsten Margrete; Bathen, Tone Frost; Tessem, May-Britt (Journal article; Peer reviewed, 2016)TMPRSS2-ERG has been proposed to be a prognostic marker for prostate cancer. The aim of this study was to identify changes in metabolism, genes and biochemical recurrence related to TMPRSS2-ERG by using an integrated ... -
Primary Treatment Effects for High-Grade Serous Ovarian Carcinoma Evaluated by Changes in Serum Metabolites and Lipoproteins
Torkildsen, Cecilie Fredvik; Austdal, Marie; Iversen, Ann-Charlotte; Bathen, Tone Frost; Giskeødegård, Guro F.; Nilsen, Elisabeth Berge; Iversen, Grete Alræk; Sande, Ragnar; Bjørge, Line; Thomsen, Liv Cecilie Vestrheim (Peer reviewed; Journal article, 2023)High-grade serous ovarian carcinoma (HGSOC) is the most common and deadliest ovarian cancer subtype. Despite advances in treatment, the overall prognosis remains poor. Regardless of efforts to develop biomarkers to predict ... -
Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy
Cao, Maria Dung; Giskeødegård, Guro F.; Bathen, Tone Frost; Sitter, Beathe; Bofin, Anna M.; Lønning, Per Eystein; Lundgren, Steinar; Gribbestad, Ingrid S (Journal article; Peer reviewed, 2012)Background Today's clinical diagnostic tools are insufficient for giving accurate prognosis to breast cancer patients. The aim of our study was to examine the tumor metabolic changes in patients with locally advanced breast ... -
Prostate-Specific Membrane Antigen PET/Magnetic Resonance Imaging for the Planning of Salvage Radiotherapy in Patients with Prostate Cancer with Biochemical Recurrence After Radical Prostatectomy
Elschot, Mattijs; Selnæs, Kirsten Margrete; Langørgen, Sverre; Johansen, Håkon; Bertilsson, Helena; Tandstad, Torgrim; Bathen, Tone Frost (Journal article; Peer reviewed, 2019)Prostate-specific membrane antigen (PSMA) PET/magnetic resonance (MR) imaging can help distinguish between patients with prostate cancer with locoregional recurrence and those with distant metastases, even at low ... -
Prostate-specific membrane antigen PET/MRI for prostate cancer: technical advancements, image interpretation, and clinical management
Abrahamsen, Bendik Skarre (Doctoral theses at NTNU;2024:97, Doctoral thesis, 2024)Prostate cancer is the most commonly diagnosed cancer in men. In the Norwegian population, it is expected that as many as one in nine men will develop prostate cancer by the age of 75. Through early detection and effective ... -
Proton magnetic resonance metabolomic characterization of ovarian serous carcinoma effusions: chemotherapy-related effects and comparison with malignant mesothelioma and breast carcinoma
Vettukattil, Riyas M; Hetland, Thea Eline; Flørenes, Vivi Ann; Kærn, Janne; Davidson, Ben; Bathen, Tone Frost (Journal article; Peer reviewed, 2013)Malignant serous effusions are a common manifestation of advanced cancer, associated with significant morbidity and mortality. The aim of this study was to identify the metabolic differences between ovarian serous carcinoma ... -
Pseudo-T2 mapping for normalization of T2-weighted prostate MRI
Sørland, Kaia Ingerdatter; Sunoqrot, Mohammed R. S.; Sandsmark, Elise; Langørgen, Sverre; Bertilsson, Helena; Trimble, Christopher George; Lin, Gigin; Selnæs, Kirsten Margrete; Goa, Pål Erik; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2022)Objective Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for quantitative analysis of multicenter data. AutoRef is an automated dual-reference ... -
A Quality Control System for Automated Prostate Segmentation on T2-Weighted MRI
Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Nketiah, Gabriel Addio; Zavala-Romero, Olmo; Stoyanova, Radka; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2020)Computer-aided detection and diagnosis (CAD) systems have the potential to improve robustness and efficiency compared to traditional radiological reading of magnetic resonance imaging (MRI). Fully automated segmentation ... -
Quantitative 31P HR-MAS MR spectroscopy for detection of response to PI3K/mTOR inhibition in breast cancer xenografts
Esmaeili, Morteza; Bathen, Tone Frost; Engebråten, Olav; Mælandsmo, Gunhild; Gribbestad, Ingrid S; Moestue, Siver Andreas (Journal article; Peer reviewed, 2014)PURPOSE: Phospholipid metabolites are of importance in cancer studies, and have been suggested as candidate metabolic biomarkers for response to targeted anticancer drugs. The purpose of this study was to develop a ... -
Quantitative prostate cancer MRI: status, challenges and opportunities
Sørland, Kaia Ingerdatter (Doctoral theses at NTNU;2024:77, Doctoral thesis, 2024)Prostate cancer was in 2020 the most frequently diagnosed cancer in men in over half of the world’s countries, and the leading cause of cancer death among men in 48 countries. Medical imaging is one of the main pillars of ... -
R2* Relaxation Affects Pharmacokinetic Analysis of Dynamic Contrast-Enhanced MRI in Cancer and Underestimates Treatment Response at 7 T
Kim, Jana; Moestue, Siver Andreas; Bathen, Tone Frost; Kim, Eugene (Journal article, 2019)Effective transverse relaxivity of gadolinium-based contrast agents is often neglected in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Here, we assess time and tissue dependence of R2* enhancement and ... -
Radiomics in psoriatic arthritis and breast cancer: Assessing disease burden and predicting survival through MR image analysis
Chronaiou, Ioanna (Doctoral theses at NTNU;2022:75, Doctoral thesis, 2022)Sammendrag Radiomics i psoriasisartritt og brystkreft: Vurdering av sykdom og prediksjon av overlevelse gjennom MR-bildeanalyser Psoriasisartritt er en kronisk inflammatorisk leddsykdom som utvikler seg hos pasienter med ... -
Reducing prostate biopsies and magnetic resonance imaging with prostate cancer risk stratification
Davik, Petter; Remmers, Sebastiaan; Elschot, Mattijs; Roobol, Monique J; Bathen, Tone Frost; Bertilsson, Helena (Journal article; Peer reviewed, 2022)