Browsing NTNU Open by Author "Bathen, Tone Frost"
Now showing items 121-140 of 143
-
Relative Enhanced Diffusivity in Prostate Cancer: Protocol Optimization and Diagnostic Potential
Billdal, Daniel Chen; While, Peter Thomas; Selnæs, Kirsten Margrete; Sunoqrot, Mohammed; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2019)Background Relative enhanced diffusivity (RED) is a potential biomarker for indirectly measuring perfusion in tissue using diffusion‐weighted magnetic resonance imaging (MRI) with 3 b values. Purpose To optimize the RED ... -
The Reproducibility of Deep Learning-Based Segmentation of the Prostate Gland and Zones on T2-Weighted MR Images
Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2021)Volume of interest segmentation is an essential step in computer-aided detection and diagnosis (CAD) systems. Deep learning (DL)-based methods provide good performance for prostate segmentation, but little is known about ... -
Restriction spectrum imaging with elastic image registration for automated evaluation of response to neoadjuvant therapy in breast cancer
Andreassen, Maren Marie Sjaastad; Loubrie, Stephane; Tong, Michelle W.; Fang, Lauren; Seibert, Tyler; Wallace, Anne M.; Zare, Somaye; Ojeda-Fournier, Haydee; Kuperman, Joshua; Hahn, Michael; Jerome, Neil Peter; Bathen, Tone Frost; Rodríguez-Soto, Ana E.; Dale, Anders; Rakow-Penner, Rebecca (Peer reviewed; Journal article, 2023)Purpose: Dynamic contrast-enhanced MRI (DCE) and apparent diffusion coefficient (ADC) are currently used to evaluate treatment response of breast cancer. The purpose of the current study was to evaluate the three-component ... -
Semi-automatic segmentation from intrinsically-registered 18F-FDG-PET/MRI for treatment response assessment in a breast cancer cohort: comparison to manual DCE-MRI
Andreassen, Maren Marie Sjaastad; Goa, Pål Erik; Sjøbakk, Torill Eidhammer; Hedayati, Roja; Eikesdal, Hans Petter; Deng, Callie; Østlie, Agnes; Lundgren, Steinar; Bathen, Tone Frost; Jerome, Neil Peter (Journal article; Peer reviewed, 2019)Objectives To investigate the reliability of simultaneous positron emission tomography and magnetic resonance imaging (PET/MRI)-derived biomarkers using semi-automated Gaussian mixture model (GMM) segmentation on PET ... -
Serum Levels of Choline-Containing Compounds Are Associated with Aerobic Fitness Level: The HUNT-Study
Bye, Anja; Vettukattil, Riyas M; Aspenes, Stian Thoresen; Giskeødegård, Guro F.; Gribbestad, Ingrid S; Wisløff, Ulrik; Bathen, Tone Frost (Journal article; Peer reviewed, 2012)Background: Cardiovascular disease (CVD) is a leading cause of death worldwide, and the number of people at risk is continuously growing. New methods for early risk prediction are therefore needed to actuate prevention ... -
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Nome, Marianne Eikhom; Euceda, Leslie R.; Jabeen, Shakila; Debik, Julia; Bathen, Tone Frost; Giskeødegård, Guro F.; Tasken, Kristin Austlid; Mælandsmo, Gunhild Mari; Halvorsen, Bente; Yndestad, Arne; Borgen, Elin; Garred, Øystein; Aukrust, Pål; Ueland, Thor; Engebraaten, Olav; Kristensen, Vessela N.; Tekpli, Xavier (Journal article; Peer reviewed, 2019)Angiogenesis is necessary for tumor growth and has been targeted in breast cancer; however, it is unclear which patients will respond and benefit from antiangiogenic therapy. We report noninvasive monitoring of patient ... -
SFRP4 gene expression is increased in aggressive prostate cancer
Sandsmark, Elise; Andersen, Maria Karoline; Bofin, Anna M.; Bertilsson, Helena; Drabløs, Finn; Bathen, Tone Frost; Rye, Morten Beck; Tessem, May-Britt (Journal article; Peer reviewed, 2017)Increased knowledge of the molecular differences between indolent and aggressive prostate cancer is needed for improved risk stratification and treatment selection. Secreted frizzled-related protein 4 (SFRP4) is a modulator ... -
Simultaneous 18F-fluciclovine Positron Emission Tomography and Magnetic Resonance Spectroscopic Imaging of Prostate Cancer
Esmaeili, Morteza; Tayari, Nassim; Scheenen, Tom WJ; Elschot, Mattijs; Sandsmark, Elise; Bertilsson, Helena; Heerschap, Arend; Selnæs, Kirsten Margrete; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)Purpose: To investigate the associations of metabolite levels derived from magnetic resonance spectroscopic imaging (MRSI) and 18F-fluciclovine positron emission tomography (PET) with prostate tissue characteristics. Methods: ... -
Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue
Andersen, Maria Karoline; Krossa, Sebastian; Høiem, Therese Stork; Buchholz, Rebecca; Claes, Britt S.R.; Balluff, Benjamin; Ellis, Shane; Richardsen, Elin; Bertilsson, Helena; Heeren, Ron M.A.; Bathen, Tone Frost; Karst, Uwe; Giskeødegård, Guro F.; Tessem, May-Britt (Journal article; Peer reviewed, 2020)Levels of zinc, along with its mechanistically related metabolites citrateand aspartate, are widely reported as reduced in prostate cancer compared to healthytissue and are therefore pointed out as potential cancer biomarkers. ... -
Skeletal muscle metabolism in rats with low and high intrinsic aerobic capacity: Effect of aging and exercise training
Shi, Mingshu; Ellingsen, Øyvind; Bathen, Tone Frost; Høydal, Morten; Koch, Lauren G.; Britton, Steven L.; Wisløff, Ulrik; Stølen, Tomas; Esmaeili, Morteza (Journal article; Peer reviewed, 2018)Purpose Exercise training increases aerobic capacity and is beneficial for health, whereas low aerobic exercise capacity is a strong independent predictor of cardiovascular disease and premature death. The purpose of ... -
Skeletal muscle metabolism in rats with low and high intrinsic aerobic capacity: Effect of aging and exercise training
Shi, Mingshu; Ellingsen, Øyvind; Bathen, Tone Frost; Høydal, Morten; Koch, Lauren G.; Britton, Steven L.; Wisløff, Ulrik; Stølen, Tomas; Esmaeili, Morteza (Peer reviewed; Journal article, 2018)Purpose Exercise training increases aerobic capacity and is beneficial for health, whereas low aerobic exercise capacity is a strong independent predictor of cardiovascular disease and premature death. The purpose of the ... -
Small LDL subfractions are associated with coronary atherosclerosis despite no differences in conventional lipids
Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna; Gjære, Sigrid; Myhra, Marthe; Vesterbekkmo, Elisabeth Kleivhaug; Wiseth, Rune; Madssen, Erik; Bye, Anja (Journal article; Peer reviewed, 2023) -
Small LDL subfractions are associated with coronary atherosclerosis despite nodifferences in conventional lipids
Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna; Gjære, Sigrid; Myhra, Marthe; Vesterbekkmo, Elisabeth Kleivhaug; Wiseth, Rune; Madssen, Erik; Bye, Anja (Peer reviewed; Journal article, 2022)Lipoprotein subfractions currently represent a new source of cardiovascular disease (CVD) risk markers that may provide more information than conventional lipid measures. We aimed to investigate whether lipoprotein ... -
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI
Andersen, Maria Karoline; Høiem, Therese Stork; Claes, Britt S.R.; Balluff, Benjamin; Marta, Martin-Lorenzo; Richardsen, Elin; Krossa, Sebastian; Bertilsson, Helena; Heeren, Ron M.A.; Rye, Morten Beck; Giskeødegård, Guro F.; Bathen, Tone Frost; Tessem, May-Britt (Peer reviewed; Journal article, 2021)Background Prostate cancer tissues are inherently heterogeneous, which presents a challenge for metabolic profiling using traditional bulk analysis methods that produce an averaged profile. The aim of this study was ... -
Spermine and Citrate as Metabolic Biomarkers for Assessing Prostate Cancer Aggressiveness
Giskeødegård, Guro F.; Bertilsson, Helena; Selnæs, Kirsten Margrete; Wright, A.J.; Bathen, Tone Frost; Viset, Trond; Halgunset, Jostein; Angelsen, Anders; Gribbestad, Ingrid S; Tessem, May-Britt (Journal article; Peer reviewed, 2013)Separating indolent from aggressive prostate cancer is an important clinical challenge for identifying patients eligible for active surveillance, thereby reducing the risk of overtreatment. The purpose of this study was ... -
Stromal collagen content in breast tumors correlates with in vivo diffusion-weighted imaging: A comparison of multi b-value DWI with histologic specimen from benign and malignant breast lesions
Egnell, Liv Elisabet; Vidic, Igor; Jerome, Neil Peter; Bofin, Anna M.; Bathen, Tone Frost; Goa, Pål Erik (Journal article; Peer reviewed, 2019)Background:Increased deposition and reorientation of stromal collagenfibers are associated with breast cancer progres-sion and invasiveness. Diffusion-weighted imaging (DWI) may be sensitive to the collagenfiber organization ... -
Support vector machine for breast cancer classification using diffusion-weighted MRI histogram features: Preliminary study.
Vidic, Igor; Egnell, Liv; Jerome, Neil Peter; Teruel, Jose Ramon; Sjøbakk, Torill Eidhammer; Østlie, Agnes; Fjøsne, Hans Erikssønn; Bathen, Tone Frost; Goa, Pål Erik (Journal article, 2017)Background Diffusion-weighted MRI (DWI) is currently one of the fastest developing MRI-based techniques in oncology. Histogram properties from model fitting of DWI are useful features for differentiation of lesions, and ... -
The Association of Tissue Steroid Hormone Levels with Body Mass Index and Endocrine Treatment Resistance in Women with Estrogen Receptor-positive Breast Cancer
Eikeland, Eline (Master thesis, 2022)Abstract will be available on 2023-07-01 -
The effect of exercise training on myocardial and skeletal muscle metabolism by MR spectroscopy in rats with heart failure
Shi, Mingshu; Ellingsen, Øyvind; Bathen, Tone Frost; Høydal, Morten; Stølen, Tomas; Esmaeili, Morteza (Journal article; Peer reviewed, 2019)he metabolism and performance of myocardial and skeletal muscle are impaired in heart failure (HF) patients. Exercise training improves the performance and benefits the quality of life in HF patients. The purpose of the ... -
The Effect of Including Bone in DIXON-based Attenuation Correction for 18F-fluciclovine PET/MRI of Prostate Cancer
Elschot, Mattijs; Selnæs, Kirsten Margrete; Johansen, Håkon; Krüger-Stokke, Brage; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)The objective of this study was to evaluate the effect of including bone in DIXON-based attenuation correction for 18F-fluciclovine Positron Emission Tomography (PET) / Magnetic Resonance Imaging (MRI) of primary and ...