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dc.contributor.authorJensen, Sanne
dc.contributor.authorMortensen, Erik L.
dc.contributor.authorSkarphedinsson, Gudmundur
dc.contributor.authorHøjgaard, David RMA
dc.contributor.authorHybel, Katja A.
dc.contributor.authorNissen, Judith B.
dc.contributor.authorIvarsson, Tord
dc.contributor.authorWeidle, Bernhard
dc.contributor.authorTorp, Nor Christian
dc.contributor.authorThomsen, Per H.
dc.identifier.citationPsychiatry Research. 2022, 317 1-9.en_US
dc.description.abstractIt is unknown if long-term remission for pediatric obsessive-compulsive disorder (OCD) patients is associated with post-treatment OCD symptom severity. The aim of the present study was to evaluate if post-treatment symptom severity cut-offs can discriminate remitters from non-remitters in pediatric OCD patients during three years of follow-up. All participants (N = 269) from the Nordic Long-term OCD Treatment Study (NordLOTS) undergoing stepped-care treatment were included. Patients were rated with the Clinical Global Impression – Severity Scale (CGI-S) one (n = 186), two (n = 167), and three years (n = 166) after first-line cognitive-behavioral therapy. Post-treatment symptom severity scores as well as percentage reductions during treatment evaluated with the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) were analyzed using receiver operating characteristics according to the CGI-S remission scores (< 2) at follow-up. Post-treatment CY-BOCS severity scores acceptably discriminated remitters from non-remitters at one-year follow-up, but poorly for the two- and three-year follow-up. Severity percentage reduction during treatment did not discriminate remission status acceptably at any follow-up point. Post-treatment OCD symptom severity status seems to have little discriminative value for long-term remission status in pediatric patients. Further research is warranted to detect post-treatment factors of prognostic value.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleLong- term remission status in pediatric obsessive-compulsive disorder: Evaluating the predictive value of symptom severity after treatmenten_US
dc.title.alternativeLong- term remission status in pediatric obsessive-compulsive disorder: Evaluating the predictive value of symptom severity after treatmenten_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.source.journalPsychiatry Researchen_US

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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal