Working Memory Training in Amnestic and Non-amnestic Patients With Mild Cognitive Impairment: Preliminary Findings From Genotype Variants on Training Effects
| dc.contributor.author | Hernes, Susanne Miriam Sørensen | |
| dc.contributor.author | Flak, Marianne Møretrø | |
| dc.contributor.author | Løhaugen, Gro Christine Christensen | |
| dc.contributor.author | Skranes, Jon Sverre | |
| dc.contributor.author | Hol, Haakon Ramsland | |
| dc.contributor.author | Madsen, Bengt-Ove | |
| dc.contributor.author | Knapskog, Anne Brita | |
| dc.contributor.author | Engvig, Andreas | |
| dc.contributor.author | Pripp, Are Hugo | |
| dc.contributor.author | Ulstein, Ingun | |
| dc.contributor.author | Lona, Trine Eli.b. | |
| dc.contributor.author | Zhang, Xin | |
| dc.contributor.author | Chang, Linda | |
| dc.date.accessioned | 2022-10-19T07:17:14Z | |
| dc.date.available | 2022-10-19T07:17:14Z | |
| dc.date.created | 2021-04-08T12:46:08Z | |
| dc.date.issued | 2021 | |
| dc.identifier.issn | 1663-4365 | |
| dc.identifier.uri | https://hdl.handle.net/11250/3026893 | |
| dc.description.abstract | Working memory training (WMT) effects may be modulated by mild cognitive impairment (MCI) subtypes, and variations in APOE-epsilon (APOE-ε) and LMX1A genotypes. Sixty-one individuals (41 men/20 women, mean age 66 years) diagnosed with MCI (31 amnestic/30 non-amnestic) and genotyped for APOE-ε and LMX1A completed 4 weeks/20-25 sessions of WMT. Cognitive functions were assessed before, 4 weeks and 16 weeks after WMT. Except for Processing Speed, the non-amnestic MCI group (naMCI) outperformed the amnestic MCI (aMCI) group in all cognitive domains across all time-points. At 4 weeks, working memory function improved in both groups (p | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Frontiers | en_US |
| dc.rights | Navngivelse 4.0 Internasjonal | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
| dc.title | Working Memory Training in Amnestic and Non-amnestic Patients With Mild Cognitive Impairment: Preliminary Findings From Genotype Variants on Training Effects | en_US |
| dc.type | Peer reviewed | en_US |
| dc.type | Journal article | en_US |
| dc.description.version | publishedVersion | en_US |
| dc.source.volume | 13 | en_US |
| dc.source.journal | Frontiers in Aging Neuroscience | en_US |
| dc.identifier.doi | 10.3389/fnagi.2021.624253 | |
| dc.identifier.cristin | 1902953 | |
| cristin.ispublished | true | |
| cristin.fulltext | original | |
| cristin.qualitycode | 1 |
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