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dc.contributor.authorVaaler, Arne
dc.contributor.authorMorken, Gunnar
dc.contributor.authorLinaker, Olav Morten
dc.contributor.authorSand, Trond
dc.contributor.authorKvistad, Kjell Arne
dc.contributor.authorBråthen, Geir
dc.date.accessioned2015-09-11T13:01:34Z
dc.date.accessioned2015-09-24T14:10:25Z
dc.date.available2015-09-11T13:01:34Z
dc.date.available2015-09-24T14:10:25Z
dc.date.issued2009
dc.identifier.citationBMC Psychiatry 2009, 9nb_NO
dc.identifier.issn1471-244X
dc.identifier.urihttp://hdl.handle.net/11250/301794
dc.description.abstractBackground: In psychiatric acute departments some patients present with brief depressive periods accompanied with fluctuating arrays of other psychiatric symptoms like psychosis, panic or mania. For the purpose of the present study we call this condition Acute Unstable Depressive Syndrome (AUDS). The aims of the present study were to compare clinical signs of organic brain dysfunctions and epilepsy in patients with AUDS and Major Depressive Episode (MDE). Methods: Out of 1038 consecutive patients admitted to a psychiatric acute ward, 16 patients with AUDS and 16 age- and gender-matched MDE patients were included in the study. Using standardized instruments and methods we recorded clinical data, EEG and MRI. Results: A history of epileptic seizures and pathologic EEG activity was more common in the AUDS group than in the MDE group (seizures, n = 6 vs. 0, p = 0.018; pathologic EEG activity, n = 8 vs. 1, p = 0.015). Five patients in the AUDS group were diagnosed as having epilepsy, whereas none of those with MDE had epilepsy (p = 0.043). There were no differences between the groups regarding pathological findings in neurological bedside examination and cerebral MRI investigation. Conclusion: Compared to patients admitted with mood symptoms fulfilling DSM 4 criteria of a major depressive disorder, short-lasting atypical depressive symptoms seem to be associated with a high frequency of epileptic and pathologic EEG activity in patients admitted to psychiatric acute departments.nb_NO
dc.language.isoengnb_NO
dc.publisherBioMed Centralnb_NO
dc.titleSymptoms of epilepsy and organic brain dysfunctions in patients with acute, brief depression combined with other fluctuating psychiatric symptoms: a controlled study from an acute psychiatric departmentnb_NO
dc.typeJournal articlenb_NO
dc.typePeer revieweden_GB
dc.date.updated2015-09-11T13:01:34Z
dc.source.volume9nb_NO
dc.source.journalBMC Psychiatrynb_NO
dc.identifier.doi10.1186/1471-244X-9-63
dc.identifier.cristin351403
dc.description.localcode© 2009 Vaaler et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.nb_NO


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