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dc.contributor.authorFossmark, Reidar
dc.contributor.authorJohannessen, Rune
dc.contributor.authorQvigstad, Gunnar
dc.contributor.authorMjønes, Patricia
dc.date.accessioned2022-04-19T10:02:17Z
dc.date.available2022-04-19T10:02:17Z
dc.date.created2022-03-23T20:12:56Z
dc.date.issued2022
dc.identifier.issn1010-660X
dc.identifier.urihttps://hdl.handle.net/11250/2991269
dc.description.abstractGastric cancer is a heterogenous group of tumours, and a better understanding of the carcinogenesis and cellular origin of the various sub-types could affect prevention and future treatment. Gastric neuroendocrine tumours (NETs) and adenocarcinomas that develop in the gastric corpus and fundus of patients with chronic atrophic gastritis have atrophic gastritis, hypoacidity, and hypergastrinemia as common risk factors and a shared cellular origin has been suggested. In particular, signet ring cell carcinomas have previously been suggested to be of neuroendocrine origin. We present a case of a combined gastric NET and signet ring cell carcinoma in a patient with hypergastrinemia due to autoimmune chronic atrophic gastritis. The occurrence of such a combined tumour strengthens the evidence that gastric NETs and signet ring cell carcinomas develop from a common origin.en_US
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleDo Gastric Signet Ring Cell Carcinomas and ECL‐Cell Neuroendocrine Tumours Have a Common Origin?en_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.volume58en_US
dc.source.journalMedicinaen_US
dc.source.issue470en_US
dc.identifier.doihttps://doi.org/10.3390/medicina58040470
dc.identifier.cristin2012126
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal