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dc.contributor.authorSánchez-Barreiro, Fátima
dc.contributor.authorGopalakrishnan, Shyam
dc.contributor.authorRamos-Madrigal, Jazmín
dc.contributor.authorWestbury, Michael V.
dc.contributor.authorde Manuel, Marc
dc.contributor.authorMargaryan, Ashot
dc.contributor.authorCiucani, Marta M.
dc.contributor.authorVieira, Filipe G.
dc.contributor.authorPatramanis, Yannis
dc.contributor.authorKalthoff, Daniela C.
dc.contributor.authorTimmons, Zena
dc.contributor.authorSicheritz-Pontén, Thomas
dc.contributor.authorDalén, Love
dc.contributor.authorRyder, Oliver A.
dc.contributor.authorZhang, Guojie
dc.contributor.authorMarquès-Bonet, Tomás
dc.contributor.authorMoodley, Yoshan
dc.contributor.authorGilbert, Marcus Thomas Pius
dc.date.accessioned2022-03-25T11:53:00Z
dc.date.available2022-03-25T11:53:00Z
dc.date.created2022-01-04T15:03:31Z
dc.date.issued2021
dc.identifier.citationMolecular Ecology. 2021, 30 (23), 6355-6369.en_US
dc.identifier.issn0962-1083
dc.identifier.urihttps://hdl.handle.net/11250/2987628
dc.description.abstractLarge vertebrates are extremely sensitive to anthropogenic pressure, and their populations are declining fast. The white rhinoceros (Ceratotherium simum) is a paradigmatic case: this African megaherbivore has suffered a remarkable decline in the last 150 years due to human activities. Its subspecies, the northern (NWR) and the southern white rhinoceros (SWR), however, underwent opposite fates: the NWR vanished quickly, while the SWR recovered after the severe decline. Such demographic events are predicted to have an erosive effect at the genomic level, linked to the extirpation of diversity, and increased genetic drift and inbreeding. However, there is little empirical data available to directly reconstruct the subtleties of such processes in light of distinct demographic histories. Therefore, we generated a whole-genome, temporal data set consisting of 52 resequenced white rhinoceros genomes, representing both subspecies at two time windows: before and during/after the bottleneck. Our data reveal previously unknown population structure within both subspecies, as well as quantifiable genomic erosion. Genome-wide heterozygosity decreased significantly by 10% in the NWR and 36% in the SWR, and inbreeding coefficients rose significantly by 11% and 39%, respectively. Despite the remarkable loss of genomic diversity and recent inbreeding it suffered, the only surviving subspecies, the SWR, does not show a significant accumulation of genetic load compared to its historical counterpart. Our data provide empirical support for predictions about the genomic consequences of shrinking populations, and our findings have the potential to inform the conservation efforts of the remaining white rhinoceroses.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsNavngivelse-Ikkekommersiell 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/deed.no*
dc.titleHistorical population declines prompted significant genomic erosion in the northern and southern white rhinoceros (Ceratotherium simum)en_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber6355-6369en_US
dc.source.volume30en_US
dc.source.journalMolecular Ecologyen_US
dc.source.issue23en_US
dc.identifier.doi10.1111/mec.16043
dc.identifier.cristin1974525
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


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Navngivelse-Ikkekommersiell 4.0 Internasjonal
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