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dc.contributor.authorPedersen, André
dc.contributor.authorValla, Marit
dc.contributor.authorBofin, Anna Mary
dc.contributor.authorPerez de Frutos, Javier
dc.contributor.authorReinertsen, Ingerid
dc.contributor.authorSmistad, Erik
dc.date.accessioned2021-04-23T11:53:27Z
dc.date.available2021-04-23T11:53:27Z
dc.date.created2021-04-14T23:47:03Z
dc.date.issued2021
dc.identifier.citationIEEE Access. 2021, 9 1-14.en_US
dc.identifier.issn2169-3536
dc.identifier.urihttps://hdl.handle.net/11250/2739350
dc.description.abstractDeep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, display and process these images. There are several open-source platforms for working with WSIs, but few support deployment of CNN models. These applications use third-party solutions for inference, making them less user-friendly and unsuitable for high-performance image analysis. To make deployment of CNNs user-friendly and feasible on low-end machines, we have developed a new platform, FastPathology, using the FAST framework and C++. It minimizes memory usage for reading and processing WSIs, deployment of CNN models, and real-time interactive visualization of results. Runtime experiments were conducted on four different use cases, using different architectures, inference engines, hardware configurations and operating systems. Memory usage for reading, visualizing, zooming and panning a WSI were measured, using FastPathology and three existing platforms. FastPathology performed similarly in terms of memory to the other C++-based application, while using considerably less than the two Java-based platforms. The choice of neural network model, inference engine, hardware and processors influenced runtime considerably. Thus, FastPathology includes all steps needed for efficient visualization and processing of WSIs in a single application, including inference of CNNs with real-time display of the results. Source code, binary releases, video demonstrations and test data can be found online on GitHub at https://github.com/SINTEFMedtek/FAST-Pathology/.en_US
dc.language.isoengen_US
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleFastPathology: An open-source platform for deep learning-based research and decision support in digital pathologyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber1-14en_US
dc.source.volume9en_US
dc.source.journalIEEE Accessen_US
dc.identifier.doi10.1109/ACCESS.2021.3072231
dc.identifier.cristin1904192
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal