• BayMeth: improved DNA methylation quantification for affinity capture sequencing data using a flexible Bayesian approach 

      Riebler, Andrea; Menigatti, Mirco; Song, Jenny Z; Statham, Aaron L; Stirzaker, Clare; Mahmud, Nadiya; Mein, Charles A; Clark, Susan J; Robinson, Mark D (Journal article; Peer reviewed, 2014)
      Affinity capture of DNA methylation combined with high-throughput sequencing strikes a good balance between the high cost of whole genome bisulfite sequencing and the low coverage of methylation arrays. We present BayMeth, ...
    • Skmer: assembly-free and alignment-free sample identification using genome skims 

      Sarmashghi, Shahab; Bohmann, Kristine; Gilbert, Marcus Thomas Pius; Bafna, Vineet; Mirarab, Siavash (Journal article; Peer reviewed, 2019)
      The ability to inexpensively describe taxonomic diversity is critical in this era of rapid climate and biodiversity changes. The recent genome-skimming approach extends current barcoding practices beyond short markers by ...
    • Ythdf2-mediated m6A mRNA clearance modulates neural development in mice 

      Li, Miaomiao; Zhao, Xu; Wang, Wei; Shi, Hailing; Pan, Qingfei; Lu, Zhike; Perez, Sonia Peña; Suganthan, Rajikala; He, Chuan; Bjørås, Magnar; Klungland, Arne (Journal article; Peer reviewed, 2018)
      Background N 6 -methyladenosine (m6A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 ...