Blar i Publikasjoner fra CRIStin - NTNU på tittel

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    • Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA-PKcs in human cells 

      Xing, Mengtan; Oksenych, Valentyn (Journal article; Peer reviewed, 2019)
      DNA double‐strand breaks (DSBs) are highly cytotoxic lesions, and unrepaired or misrepaired DSBs can lead to various human diseases, including immunodeficiency, neurological abnormalities, growth retardation, and cancer. ...

    • Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models 

      Castaneda Zegarra, Sergio Miguel; Fernandez Berrocal, Marion Silvana; Tkachev, Max; Yao, Rouan; Esnardo Upfold, Nikki Lyn; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)
      Non-homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double-strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J ...

    • Genetic Load and Adaptive Potential of a Recovered Avian Species that Narrowly Avoided Extinction 

      Femerling, Georgette; van Oosterhout, Cock; Feng, Shaohong; Bristol, Rachel M.; Zhang, Guojie; Groombridge, Jim; Gilbert, Marcus Thomas Pius; Morales, Hernán E (Journal article; Peer reviewed, 2023)
      High genetic diversity is a good predictor of long-term population viability, yet some species persevere despite having low genetic diversity. Here we study the genomic erosion of the Seychelles paradise flycatcher ...

    • Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies 

      Gorski, Mathias; Rasheed, Humaira; Teumer, Alexander; Thomas, Laurent; Graham, Sarah E.; Sveinbjornsson, Gardar; Winkler, Thomas W.; Günther, Felix; Stark, Klaus J.; Chai, Jin-Fang; Tayo, Bamidele O.; Wuttke, Matthias; Li, Yong; Tin, Adrienne; Ahluwalia, Tarunveer S.; Ärnlöv, Johan; Åsvold, Bjørn Olav; Bakker, Stephan J.L.; Banas, Bernhard; Bansal, Nisha; Biggs, Mary L.; Biino, Ginevra; Böhnke, Michael; Boerwinkle, Eric; Bottinger, Erwin P.; Brenner, Hermann; Brumpton, Ben Michael; Carroll, Robert J.; Chaker, Layal; Chalmers, John; Chee, Miao-Li; Chee, Miao-Ling; Cheng, Ching-Yu; Chu, Audrey Y.; Ciullo, Marina; Cocca, Massimiliano; Cook, James P.; Coresh, Josef; Cusi, Daniele; de Borst, Martin H.; Degenhardt, Frauke; Eckardt, Kai-Uwe; Endlich, Karlhans; Evans, Michele K.; Feitosa, Mary F.; Franke, Andre; Freitag-Wolf, Sandra; Fuchsberger, Christian; Gampawar, Piyush; Gansevoort, Ron T.; Ghanbari, Mohsen; Ghasemi, Sahar; Giedraitis, Vilmantas; Gieger, Christian; Gudbjartsson, Daniel F.; Hallan, Stein; Hamet, Pavel; Hishida, Asahi; Ho, Kevin; Hofer, Edith; Holleczek, Bernd; Holm, Hilma; Hoppmann, Anselm; Horn, Katrin; Hutri-Kähönen, Nina; Hveem, Kristian; Hwang, Shih-Jen; Ikram, M. Arfan; Josyula, Navya Shilpa; Jung, Bettina; Kähönen, Mika; Karabegović, Irma; Khor, Chiea-Chuen; Koenig, Wolfgang; Kramer, Holly; Krämer, Bernhard K.; Kühnel, Brigitte; Kuusisto, Johanna; Laakso, Markku; Lange, Leslie A.; Lehtimäki, Terho; Li, Man; Lieb, Wolfgang; Lind, Lars; Lindgren, Cecilia M.; Loos, Ruth J.F.; Lukas, Mary Ann; Lyytikäinen, Leo-Pekka; Mahajan, Anubha; Matias-Garcia, Pamela R.; Meisinger, Christa; Meitinger, Thomas; Melander, Olle; Milaneschi, Yuri; Mishra, Pashupati P.; Mononen, Nina; Morris, Andrew P.; Mychaleckyj, Josyf C.; Nadkarni, Girish N.; Naito, Mariko; Nakatochi, Masahiro; Nalls, Mike A.; Nauck, Matthias; Nikus, Kjell; Ning, Boting; Nolte, Ilja M.; Nutile, Teresa; O'Donoghue, Michelle L.; O'Connell, Jeffrey; Olafsson, Isleifur; Orho-Melander, Marju; Parsa, Afshin; Pendergrass, Sarah A.; Penninx, Brenda W.J.H.; Pirastu, Mario; Preuss, Michael H.; Psaty, Bruce M.; Raffield, Laura M.; Raitakari, Olli T.; Rheinberger, Myriam; Rice, Kenneth M.; Rizzi, Federica; Rosenkranz, Alexander R.; Rossing, Peter; Rotter, Jerome I.; Ruggiero, Daniela; Ryan, Kathleen A.; Sabanayagam, Charumathi; Salvi, Erika; Schmidt, Helena; Schmidt, Reinhold; Scholz, Markus; Schöttker, Ben; Schulz, Christina-Alexandra; Sedaghat, Sanaz; Shaffer, Christian M.; Sieber, Karsten B.; Sim, Xueling; Sims, Mario; Snieder, Harold; Stanzick, Kira J.; Thorsteinsdottir, Unnur; Stocker, Hannah; Strauch, Konstantin; Stringham, Heather M.; Sulem, Patrick; Szymczak, Silke; Taylor, Kent D.; Thio, Chris H.L.; Tremblay, Johanne; Vaccargiu, Simona; van der Harst, Pim; van der Most, Peter J.; Verweij, Niek; Völker, Uwe; Wakai, Kenji; Waldenberger, Melanie; Wallentin, Lars; Wallner, Stefan; Wang, Judy; Waterworth, Dawn M.; White, Harvey D.; Willer, Cristen J.; Wong, Tien-Yin; Woodward, Mark; Yang, Qiong; Yerges-Armstrong, Laura M.; Zimmermann, Martina; Zonderman, Alan B.; Bergler, Tobias; Stefansson, Kari; Böger, Carsten A.; Pattaro, Cristian; Köttgen, Anna; Kronenberg, Florian; Heid, Iris M. (Peer reviewed; Journal article, 2022)
      Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci from genome-wide association studies ...

    • Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study 

      Pingault, Jean-Baptiste; Barkhuizen, Wikus; Wang, Biyao; Hannigan, Laurie John; Eilertsen, Espen Moen; Corfield, Elizabeth Claire; Andreassen, Ole; Ask, Helga; Tesli, Martin Steen; Askeland, Ragna Bugge; Davey Smith, George; Stoltenberg, Camilla; Davies, Neil M.; Reichborn-Kjennerud, Ted; Ystrøm, Eivind; Havdahl, Alexandra (Peer reviewed; Journal article, 2022)
      Identifying mechanisms underlying the intergenerational transmission of risk for attention-deficit/hyperactivity disorder (ADHD) traits can inform interventions and provide insights into the role of parents in shaping their ...

    • The genetic organization of longitudinal subcortical volumetric change is stable throughout the lifespan running title: Genetics of subcortical lifespan change 

      Fjell, Anders Martin; Grydeland, Håkon; Wang, Yunpeng; Amlien, Inge; Bartrés-Faz, David; Brandmaier, Andreas M.; Düzel, Sandra; Elman, Jeremy; Franz, Carol; Håberg, Asta; Kietzmann, Tim C.; Kievit, Rogier A.; Kremen, William S.; Krogsrud, Stine Kleppe; Kühn, Simone; Lindenberger, Ulman; Macià, Didac; Mowinckel, Athanasia Monika; Nyberg, Lars; Panizzon, Matthew S.; Solé-Padullés, Cristina; Sørensen, Øystein; Westerhausen, Rene; Walhovd, Kristine B (Peer reviewed; Journal article, 2021)
      Development and aging of the cerebral cortex show similar topographic organization and are governed by the same genes. It is unclear whether the same is true for subcortical regions, which follow fundamentally different ...

    • Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes 

      Drange, Ole Kristian; Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Finseth, Per Ivar; Witoelar, Aree; Frei, Oleksandr; Wang, Yunpeng; Hassani, Sahar; Djurovic, Srdjan; Dale, Anders M; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2019)
      Background: Alzheimer’s disease (AD) and bipolar disorder (BIP) are complex traits influenced by numerous common genetic variants, most of which remain to be detected. Clinical and epidemiological evidence suggest that AD ...

    • Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes 

      Drange, Ole Kristian; Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Finseth, Per Ivar; Witoelar, Aree; Frei, Oleksandr; Psychiatric Genomic Consortium, Bipolar Disorder Working Group; Wang, Yunpeng; Hassani, Sahar; Srdjan, Djurovic; Dale, Anders; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2019)
      Background: Alzheimer’s disease (AD) and bipolar disorder (BIP) are complex traits influenced by numerous common genetic variants, most of which remain to be detected. Clinical and epidemiological evidence suggest that AD ...

    • Genetic polymorphisms associated with sleep-related phenotypes; relationships with individual nocturnal symptoms of insomnia in the HUNT study 

      Bragantini, Daniela; Sivertsen, Børge; Gehrman, Philip; Lydersen, Stian; Guzey, Ismail Cuneyt (Journal article; Peer reviewed, 2019)
      Background In recent years, several GWAS (genome wide association studies) of sleep-related traits have identified a number of SNPs (single nucleotides polymorphism) but their relationships with symptoms of insomnia are ...

    • Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women 

      Steinthorsdottir, Valgerdur; McGinnis, Ralph; Williams, Nicholas O.; Stefánsdóttir, Lilja; Thorleifsson, Gudmar; Shooter, Scott; Fadista, João; Sigurdsson, Jon K.; Auro, Kirsi; Berezina, Galina; Borges, Maria-Carolina; Bumpstead, Suzannah; Bybjerg-Grauholm, Jonas; Colgiu, Irina; Dolby, Vivien A.; Dudbridge, Frank; Engel, Stephanie M.; Franklin, Christopher S.; Frigge, Michael L; Frisbaek, Yr; Geirsson, Reynir T.; Geller, Frank; Gretarsdottir, Solveig; Gudbjartsson, Daniel F.; Harmon, Quaker; Hougaard, David Michael; Hegay, Tatyana; Helgadottir, Anna; Hjartardóttir, Sigrún; Jääskeläinen, Tiina; Johannsdottir, Hrefna; Jonsdottir, Ingileif; Juliusdottir, Thorhildur; Kalsheker, Noor; Kasimov, Abdumadjit; Kemp, John P.; Kivinen, Katja; Klungsøyr, Kari; Lee, Wai K; Melbye, Mads; Miedzybrodska, Zosia; Moffett, Ashley; Najmutdinova, Dilbar; Nishanova, Firuza; Olafsdottir, Thorunn; Perola, Markus; Pipkin, Fiona Broughton; Poston, Lucilla; Prescott, Gordon; Saevarsdottir, Saedis; Salimbayeva, Damilya; Scaife, Paula Juliet; Skotte, Line; Staines-Urias, Eleonora; Stefansson, Olafur A.; Sørensen, Karina Meden; Thomsen, Liv Cecilie Vestrheim; Tragante, Vinicius; Trogstad, Lill; Simpson, Nigel A.B.; Aripova, Tamara; Casas, Juan P; Dominiczak, Anna F; Walker, James J.; Thorsteinsdottir, Unnur; Iversen, Ann-Charlotte; Feenstra, Bjarke; Lawlor, Deborah A.; Boyd, Heather Allison; Magnus, Per; Laivuori, Hannele; Zakhidova, Nodira; Syvatova, Gulnara; Stefansson, Kari; Morgan, Linda (Peer reviewed; Journal article, 2020)
      Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate ...

    • A genetic programming approach for searching on nearest neighbors graphs 

      Muñoz, Javier A. Vargas; Dias, Zanoni; Torres, Ricardo (Peer reviewed; Journal article, 2022)
      Nearest neighbors graphs have gained a lot of attention from the information retrieval community since they were demonstrated to outperform classical approaches in the task of approximate nearest neighbor search. These ...

    • Genetic rescue of an endangered domestic animal through outcrossing with closely related breeds: A case study of the Norwegian Lundehund 

      Stronen, Astrid Vik; Salmela, Elina; Baldursdottir, Birna K.; Berg, Peer; Espelien, Ingvild S.; Jarvi, Kirsi; Jensen, Henrik; Kristensen, Torsten N.; Melis, Claudia; Manenti, Tommaso; Lohi, Hannes; Pertoldi, Cino (Journal article; Peer reviewed, 2017)
      Genetic rescue, outcrossing with individuals from a related population, is used to augment genetic diversity in populations threatened by severe inbreeding and extinction. The endangered Norwegian Lundehund dog underwent ...

    • Genetic Rescue of the Highly Inbred Norwegian Lundehund 

      Melis, Claudia; Pertoldi, Cino; Ludington, William Basil; Beuchat, Carol; Qvigstad, Gunnar; Stronen, Astrid Vik (Journal article; Peer reviewed, 2022)
      Augmenting the genetic diversity of small, inbred populations by the introduction of new individuals is often termed “genetic rescue“. An example is the Norwegian Lundehund, a small spitz dog with inbreeding-related health ...

    • Genetic risk score associations for myocardial infarction are comparable in persons with and without rheumatoid arthritis: the population-based HUNT study 

      Rostami, Sina; Hoff, Mari; Dalen, Håvard; Hveem, Kristian; Videm, Vibeke (Peer reviewed; Journal article, 2020)
      Persons with rheumatoid arthritis (RA) have increased risk of myocardial infarction (MI). Overlapping associations with MI of weighted genetic risk scores (wGRS) for coronary artery disease (CAD) and RA is unknown in a ...

    • Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache 

      Harder, Aster V.E.; Winsvold, Bendik K S; Noordam, Raymond; Vijfhuizen, Lisanne S.; Børte, Sigrid; Kogelman, Lisette J.A.; de Boer, Irene; Tronvik, Erling Andreas; Rosendaal, Frits; Willems van Dijk, Ko; O'Connor, Emer; Fourier, Carmen; Thomas, Laurent; Kristoffersen, Espen Saxhaug; Fronczek, Rolf; Pozo-Rosich, Patricia; Jensen, Rigmor; Ferrari, Michel D.; Hansen, Thomas; Zwart, John-Anker; Terwindt, Gisela M.; van den Maagdenberg, Arn M.J.M (Peer reviewed; Journal article, 2021)
      Objective Identifying common genetic variants that confer genetic risk for cluster headache. Methods We conducted a case–control study in the Dutch Leiden University Cluster headache neuro-Analysis program (LUCA) study ...

    • Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae 

      Drejer, Eivind Bøe; Hakvåg, Sigrid; Irla, Marta Katarzyna; Brautaset, Trygve (Journal article; Peer reviewed, 2018)
      Although Escherichia coli and Bacillus subtilis are the most prominent bacterial hosts for recombinant protein production by far, additional species are being explored as alternatives for production of difficult-to-express ...

    • Genetic variability and structure of the water vole Arvicola amphibius across four metapopulations in northern Norway 

      Melis, Claudia; Borg, Åsa Alexandra; Jensen, Henrik; Bjørkvoll, Eirin Marie; Ringsby, Thor Harald; Sæther, Bernt-Erik (Journal article; Peer reviewed, 2013)
      Water vole Arvicola amphibius populations have recently experienced severe decline in several European countries as a consequence of both reduction in suitable habitat and the establishment of the alien predator American ...

    • Genetic variability at isozyme loci in two gadoid species; whiting (Merlangus merlangus L.) and saithe (Pollachius virens L.) from the Norwegian coast 

      Forthun, Jo; Mork, Jarle (Journal article, 1997)

    • Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study 

      Fjukstad, Katrine Kveli; Athanasiu, Lavinia; Bahrami, Shahram; O`Connell, Kevin; van der Meer, Dennis; Bettella, Francesco; Dieset, Ingrid; Steen, Nils Eiel; Djurovic, Srdjan; Spigset, Olav; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2021)
      Selective serotonin reuptake inhibitors (SSRIs) are prescribed both to patients with schizophrenia and bipolar disorder. Previous studies have shown associations between SSRI treatment and cardiometabolic alterations. The ...

    • Genetic variants related to physical activity or sedentary behaviour: a systematic review 

      Aasdahl, Lene; Nilsen, Tom Ivar Lund; Meisingset, Ingebrigt; Nordstoga, Anne Lovise; Evensen, Kari Anne Indredavik; Paulsen, Julie; Mork, Paul Jarle; Skarpsno, Eivind S. (Peer reviewed; Journal article, 2021)
      Background Research shows that part of the variation in physical activity and sedentary behaviour may be explained by genetic factors. Identifying genetic variants associated with physical activity and sedentary behaviour ...