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dc.contributor.authorRobsahm, Trude Eid
dc.contributor.authorFalk, Ragnhild Sørum
dc.contributor.authorHeir, Trond
dc.contributor.authorSandvik, Leiv
dc.contributor.authorVos, Linda
dc.contributor.authorErikssen, Jan Emil
dc.contributor.authorTretli, Steinar
dc.date.accessioned2020-04-17T07:36:44Z
dc.date.available2020-04-17T07:36:44Z
dc.date.created2017-01-18T10:14:27Z
dc.date.issued2016
dc.identifier.citationCancer Medicine. 2016, 5 (8), 2136-2144.en_US
dc.identifier.issn2045-7634
dc.identifier.urihttps://hdl.handle.net/11250/2651434
dc.description.abstractPhysical activity is inversely associated with risk of some cancers. The relation with cancer‐specific death remains uncertain. Mainly, studies on relationships between physical activity and cancer are based on self‐reported physical activity (SPA). Hereby, we examined whether measured cardiorespiratory fitness (CRF) is associated with cancer risk, mortality, and case fatality. We also describe relationships between SPA and these outcomes, and between CRF and SPA. A cohort of 1997 healthy Norwegian men, aged 40–59 years at inclusion in 1972–75, was followed throughout 2012. At baseline, CRF was objectively measured. SPA (leisure time and occupational) was obtained through a questionnaire. Relationships between CRF or SPA, and the outcomes were estimated using Cox regression, adjusted for age, body mass index (BMI), and smoking. Pearson correlation coefficients evaluated agreements between CRF and SPA. During follow‐up, 758 men were diagnosed with cancer and 433 cancer deaths occurred. Analyses revealed lower cancer risk (Hazard ratio [HR] 0.85, 95% confidence intervals [CI]: 0.68–1.00), mortality (HR 0.68, 95% CI: 0.53–0.88), and case fatality (HR 0.74, 95% CI: 0.57–0.96), in men with high CRF compared to low CRF. Light leisure time SPA was associated with lower cancer risk (HR 0.70, 95% CI: 0.56–0.86) and mortality (HR 0.64 95% CI: 0.49–0.83), whereas strenuous occupational SPA was associated with higher risks (HR 1.42, 95% CI: 1.13–1.78 and HR 1.45, 95% CI: 1.09–1.93). Correlations between CRF and SPA were 0.351 (P < 0.001) and −0.106 (P < 0.001) for leisure time and occupational SPA, respectively. A high midlife CRF may be beneficial for cancer risk, cancer mortality, and case fatality.en_US
dc.language.isoengen_US
dc.publisherJohn Wiley & Sonsen_US
dc.relation.urihttp://onlinelibrary.wiley.com/doi/10.1002/cam4.773/epdf
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleMeasured cardiorespiratory fitness and self-reported physical activity: associations with cancer risk and death in a long-term prospective cohort studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber2136-2144en_US
dc.source.volume5en_US
dc.source.journalCancer Medicineen_US
dc.source.issue8en_US
dc.identifier.doi10.1002/cam4.773
dc.identifier.cristin1430442
dc.description.localcodeThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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