Vis enkel innførsel

dc.contributor.authorBravo, Natalia
dc.contributor.authorGrimalt, Joan O.
dc.contributor.authorChashchin, Max
dc.contributor.authorChashchin, Valery
dc.contributor.authorOdland, Jon Øyvind
dc.date.accessioned2020-02-07T07:08:45Z
dc.date.available2020-02-07T07:08:45Z
dc.date.created2019-07-21T15:49:57Z
dc.date.issued2019
dc.identifier.citationEnvironment International. 2019, 124 541-552.nb_NO
dc.identifier.issn0160-4120
dc.identifier.urihttp://hdl.handle.net/11250/2640130
dc.description.abstractBackground One of the most worrying consequence of the production and use of persistent organohalogen pollutants (POPs) is the high accumulation in Arctic populations because of long-range transport. Study of the effects in these populations may illustrate human impacts that are difficult to assess in other locations with lower exposure to these compounds and more diverse pollutant influences. Objective We aimed to identify the main maternal characteristics influencing on the accumulation of these compounds and the effects on the newborns in a highly exposed Arctic population (Chukotka, Russia). Methods Organochlorine and organobromine compounds were analysed in maternal venous serum (n = 250). The study included data on residence, educational level, age, parity and body mass index (BMI) from self-reported questionnaires and measured anthropometric characteristics of newborns. Results Concentrations of β-hexachlorocyclohexanes, hexachlorobenzene, 4,4′-DDT and polychlorobiphenyls were high when compared with those generally found in adult populations later than year 2000. The polybromodiphenyl ethers were negligible. These POP concentrations were higher than in Alaska and Arctic Norway and similar to those in Canada. The Chukotka mothers living in inland areas showed significant lower concentrations than those living in the coast (p < 0.001) except for 4,4′-DDT. The population from the Chukotsky District, a specific coastal area, showed the highest concentrations. Residence was therefore a main concentration determinant (p < 0.001) followed by maternal age, and in some cases parity and BMI (p < 0.05). 4,4′-DDT showed an association with the anthropometric characteristics of the newborns (p < 0.05). Mothers with higher 4,4′-DDT concentrations had longer gestational ages and gave birth to infants with higher weight and length. Conclusions The maternal accumulation patterns of POPs were mainly related with residence. Most of these compounds were found in higher concentration in women living at coastal areas except 4,4′-DDE and 4,4′-DDT which were of inland origin. This last pesticide was the pollutant showing positive associations with gestational age and newborn's weight and length. To the best of our knowledge, this is the first study reporting statistically significant associations between maternal 4,4′-DDT exposure and anthropometric characteristics of the newborns.nb_NO
dc.language.isoengnb_NO
dc.publisherElseviernb_NO
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.no*
dc.titleDrivers of maternal accumulation of organohalogen pollutants in Arctic areas (Chukotka, Russia) and 4,4′-DDT effects on the newbornsnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.pagenumber541-552nb_NO
dc.source.volume124nb_NO
dc.source.journalEnvironment Internationalnb_NO
dc.identifier.doi10.1016/j.envint.2019.01.049
dc.identifier.cristin1712220
dc.description.localcodeThis article is available under the Creative Commons CC-BY-NC-ND license and permits non-commercial use of the work as published, without adaptation or alteration provided the work is fully attributed.nb_NO
cristin.unitcode194,65,20,0
cristin.unitnameInstitutt for samfunnsmedisin og sykepleie
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
Med mindre annet er angitt, så er denne innførselen lisensiert som Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal