dc.contributor.author | Forsberg, Zarah | |
dc.contributor.author | Sørlie, Morten | |
dc.contributor.author | Petrovic, Dejan | |
dc.contributor.author | Courtade, Gaston | |
dc.contributor.author | Aachmann, Finn Lillelund | |
dc.contributor.author | Vaaje-Kolstad, Gustav | |
dc.contributor.author | Bissaro, Bastien | |
dc.contributor.author | Kjendseth, Åsmund Røhr | |
dc.contributor.author | Eijsink, Vincent | |
dc.date.accessioned | 2020-01-03T07:04:20Z | |
dc.date.available | 2020-01-03T07:04:20Z | |
dc.date.created | 2019-05-31T16:36:26Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Current Opinion in Structural Biology. 2019, 59 54-64. | nb_NO |
dc.identifier.issn | 0959-440X | |
dc.identifier.uri | http://hdl.handle.net/11250/2634677 | |
dc.description.abstract | The discovery of oxidative cleavage of glycosidic bonds by enzymes currently known as lytic polysaccharide monooxygenases (LPMOs) has had a major impact on our current understanding of the enzymatic conversion of recalcitrant polysaccharides such as chitin and cellulose. The number of LPMO sequence families keeps expanding and novel substrate specificities and biological functionalities are being discovered. The catalytic mechanism of these LPMOs remains somewhat enigmatic. Recently, novel insights have been obtained from studies of enzyme–substrate complexes by X-ray crystallography, EPR, NMR, and modeling. Furthermore, it has been shown that LPMOs may carry out peroxygenase reactions, at much higher rates than monooxygenase reactions, which affects our understanding and exploitation of these powerful enzymes. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Elsevier | nb_NO |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | Polysaccharide degradation by lytic polysaccharide monooxygenases | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 54-64 | nb_NO |
dc.source.volume | 59 | nb_NO |
dc.source.journal | Current Opinion in Structural Biology | nb_NO |
dc.identifier.doi | 10.1016/j.sbi.2019.02.015 | |
dc.identifier.cristin | 1701942 | |
dc.relation.project | Norges forskningsråd: 247001 | nb_NO |
dc.relation.project | Norges forskningsråd: 247730 | nb_NO |
dc.relation.project | Norges forskningsråd: 243663 | nb_NO |
dc.relation.project | Norges forskningsråd: 243950 | nb_NO |
dc.relation.project | Norges forskningsråd: 257622 | nb_NO |
dc.relation.project | Norges forskningsråd: 240967 | nb_NO |
dc.relation.project | Norges forskningsråd: 256766 | nb_NO |
dc.relation.project | Norges forskningsråd: 268002 | nb_NO |
dc.relation.project | Norges forskningsråd: 262853 | nb_NO |
dc.relation.project | Norges forskningsråd: 221576 | nb_NO |
dc.description.localcode | © 2019 The Authors. Published by Elsevier Ltd. This article is available under the Creative Commons CC-BY-NC-ND license and permits non-commercial use of the work as published, without adaptation or alteration provided the work is fully attributed. | nb_NO |
cristin.unitcode | 194,66,15,0 | |
cristin.unitname | Institutt for bioteknologi og matvitenskap | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |