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dc.contributor.authorVik, Sigrid Dannheim
dc.contributor.authorTorp, Hans
dc.contributor.authorFollestad, Turid
dc.contributor.authorStøen, Ragnhild
dc.contributor.authorNyrnes, Siri Ann
dc.date.accessioned2019-11-20T08:41:05Z
dc.date.available2019-11-20T08:41:05Z
dc.date.created2019-08-27T08:51:37Z
dc.date.issued2019
dc.identifier.issn0031-3998
dc.identifier.urihttp://hdl.handle.net/11250/2629400
dc.description.abstractBACKGROUND: There is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates. NeoDoppler is a novel ultrasound system, which can be gently fixed to the anterior fontanel and measure cerebral blood flow velocity continuously in different depths of the brain simultaneously. We aimed to study the feasibility, accuracy, and potential clinical applications of NeoDoppler in preterm infants and sick neonates. METHOD: Twenty-five infants born at different gestational ages with a variety of diagnoses on admission were included. The probe was placed over the anterior fontanel, and blood flow velocity data were continuously recorded. To validate NeoDoppler, we compared the measurements with conventional ultrasound; agreement was assessed using Bland-Altman plots. RESULTS: NeoDoppler can provide accurate and continuous data on cerebral blood flow velocity in several depths simultaneously. Limits of agreement between the measurements obtained with the two methods were acceptable. CONCLUSION: By monitoring the cerebral circulation continuously, increased knowledge of cerebral hemodynamics in preterm infants and sick neonates may be acquired. Improved monitoring of these vulnerable brains during a very sensitive period of brain development may contribute toward preventing brain injuries.nb_NO
dc.description.abstractNeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates.nb_NO
dc.language.isoengnb_NO
dc.publisherNature Researchnb_NO
dc.relation.urihttps://www.nature.com/articles/s41390-019-0535-0
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleNeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates.nb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.journalPediatric Researchnb_NO
dc.identifier.doi10.1038/s41390-019-0535-0
dc.identifier.cristin1718920
dc.relation.projectUniversiteter/Høyskoler: 81770842nb_NO
dc.description.localcode© The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)nb_NO
cristin.unitcode1920,1,0,0
cristin.unitcode194,65,25,0
cristin.unitcode194,65,1,0
cristin.unitcode194,65,15,0
cristin.unitcode194,65,0,0
cristin.unitnameBarne- og ungdomsklinikken
cristin.unitnameInstitutt for sirkulasjon og bildediagnostikk
cristin.unitnameMH fakultetsadministrasjon
cristin.unitnameInstitutt for klinisk og molekylær medisin
cristin.unitnameFakultet for medisin og helsevitenskap
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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