• 1-year follow-up of 920 hip and knee arthroplasty patients after implementing fast-track: Good outcomes in a Norwegian university hospital 

      Winther, Siri Bjørgen; Foss, Olav A.; Wik, Tina Strømdal; Davis, Shawn Patric; Engdal, Monika; Jessen, Vigleik; Husby, Otto Schnell (Journal article; Peer reviewed, 2015)
      Background — Fast–track has become a well–known concept resulting in improved patient satisfaction and postoperative results. Concerns have been raised about whether increased efficiency could compromise safety, and whether ...
    • 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...
    • 18F-FACBC PET/MRI in the evaluation of human brain metastases: a case report 

      Johannessen, Knut; Berntsen, Erik Magnus; Johansen, Håkon; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2021)
      Abstract Background: Patients with metastatic cancer to the brain have a poor prognosis. In clinical practice, MRI is used to delineate, diagnose and plan treatment of brain metastases. However, MRI alone is limited in ...
    • 2-hydroxyglutarate as a magnetic resonance biomarker for glioma subtyping 

      Esmaeili, Morteza; Vettukattil, Riyas M; Bathen, Tone Frost (Journal article; Peer reviewed, 2013)
      Mutations in the isocitrate dehydrogenase (IDH) genes are frequently found in gliomas and in a fraction of acute myeloid leukemia patients. This results in the production of an oncometabolite, 2-hydroxyglutarate (2-HG). ...
    • 2018 international consensus meeting on musculoskeletal infection: Summary from the biofilm workgroup and consensus on biofilm related musculoskeletal infections 

      Saeed, Kordo; McLaren, Alex C; Schwarz, Edward M; Antoci, Valentin; Arnold, William V; Chen, Antonia F; Clauss, Martin; Esteban, Jaime; Gant, Vanya; Hendershot, Edward; Hickok, Noreen; Higuera, Carlos A; Coraca-Huber, Debora C; Choe, Hyonmin; Jennings, Jessica A; Joshi, Manjari; Li, William T; Noble, Philip C; Phillips, K Scott; Pottinger, Paul S; Restrepo, Camilo; Rohde, Holger; Schaer, Thomas P; Shen, Hao; Smeltzer, Mark; Stoodley, Paul; Webb, Jason C J; Witsø, Eivind (Peer reviewed; Journal article, 2019)
      Biofilm-associated implant-related bone and joint infections are clinically important due to the extensive morbidity, cost of care and socioeconomic burden that they cause. Research in the field of biofilms has expanded ...
    • 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery. 

      Wahba, Alexander; Milojevic, Milan; Boer, Christa; De Somer, Filip M.J.J.; Gudbjartsson, Tomas; van den Goor, Jenny; Jones, Timothy J.; Lomivorotov, Vladimir; Merkle, Frank; Ranucci, Marco; Kunst, Gudrun; Puis, Luc (Peer reviewed; Journal article, 2019)
    • 30-day mortality in patients after hip fracture surgery: A comparison of the Charlson Comorbidity Index score and ASA score used in two prediction models 

      Haugan, Kristin; Klaksvik, Jomar; Foss, Olav A. (Peer reviewed; Journal article, 2021)
      Objective: To compare the Charlson Comorbidity Index (CCI) and American Society of Anesthesiologists (ASA) Physical Status Classification used in two prediction models for 30-day mortality after hip fracture surgery. Study ...
    • A 39 kb structural variant causing Lynch Syndrome detected by optical genome mapping and nanopore sequencing 

      Bjørnstad, Pål Marius; Aaløkken, Ragnhild Margrethe; Åsheim, June; Sundaram, Arvind; Nangota Felde, Caroline; Østby, Gina Henriette; Dalland, Marianne; Sjursen, Wenche; Carrizosa, Christian; Vigeland, Magnus Dehli; Sorte, Hanne Sørmo; Sheng, Ying; Ariansen, Sarah Louise; Grindedal, Eli Marie; Gilfillan, Gregor (Peer reviewed; Journal article, 2023)
      Lynch Syndrome (LS) is a hereditary cancer syndrome caused by pathogenic germline variants in one of the four mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2. It is characterized by a significantly increased risk of ...
    • 3D image guided adaptive brachytherapy in patients with locally advanced cervical cancer: experience and clinical results from a minimum of six years of follow-up 

      Sundset, Marit; Wanderås, Anne Dybdahl; Danielsen, Signe; Alsaker, Mirjam Delange; Hagen, Bjørn; Marthinsen, Anne Beate Langeland (Peer reviewed; Journal article, 2021)
      In 2005, individualized 3D image guided brachytherapy was implemented for cervical cancer patients, in accordance with the (GYN) GEC ESTRO recommendation, at St. Olav's Hospital, Trondheim, Norway. This study reports the ...
    • 3D Myocardial Mechanical Wave Measurements: Toward In Vivo 3D Myocardial Elasticity Mapping 

      Salles, Sebastien; Espeland, Torvald; Rodriguez-Molares, Alfonso; Aase, Svein Arne; Hammer, Tommy; Støylen, Asbjørn; Aakhus, Svend; Løvstakken, Lasse; Torp, Hans (Peer reviewed; Journal article, 2020)
      Objectives This study aimed to investigate the potential of a novel 3-dimensional (3D) mechanical wave velocity mapping technique, based on the natural mechanical waves produced by the heart itself, to approach a noninvasive ...
    • 5 Years of Exercise Intervention Did Not Benefit Cognition Compared to the Physical Activity Guidelines in Older Adults, but Higher Cardiorespiratory Fitness Did. A Generation 100 Substudy 

      Sokołowski, Daniel; Hansen, Tor Ivar; Rise, Henning Hoel; Reitlo, Line Skarsem; Wisløff, Ulrik; Stensvold, Dorthe; Håberg, Asta (Peer reviewed; Journal article, 2021)
      Background: Aerobic exercise is proposed to attenuate cognitive decline in aging. We investigated the effect of different aerobic exercise interventions and cardiorespiratory fitness (CRF) upon cognition throughout a 5-year ...
    • A 36-month follow-up of decline in activities of daily living in individuals receiving domiciliary care 

      Helvik, Anne-Sofie; Høgset, Lisbeth Dyrendal; Bergh, Sverre; Saltyte Benth, Jurate; Kirkevold, Øyvind; Selbæk, Geir (Journal article; Peer reviewed, 2015)
      Background There have been few studies of how personal and instrumental activities of daily living (P-ADL and I-ADL) develop over time in older people receiving domiciliary care. This study aimed at assessing variables ...
    • A balanced tissue composition reveals new metabolic and gene expression markers in prostate cancer 

      Tessem, May-Britt; Bertilsson, Helena; Angelsen, Anders; Bathen, Tone Frost; Drabløs, Finn Sverre; Rye, Morten Beck (Journal article; Peer reviewed, 2016)
      Molecular analysis of patient tissue samples is essential to characterize the in vivo variability in human cancers which are not accessible in cell-lines or animal models. This applies particularly to studies of tumor ...
    • A European multicentre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts 

      Hayes, A; Nguyen, Dung; Andersson, Monique; Antón, Andres; Bailly, Jean-Luc; Beard, Stuart; Benschop, Kimberley; Berginc, Natasa; Blomqvist, Soile; Cunningham, Emma; Davis, D; Dembinski, Jennifer Lynn; Diedrich, Sabine; Dudman, Susanne Marie Rogne Gjeruldsen; Dyrdak, R; Eltringham, G. J. A.; Gonzales-Goggia, S; Gunson, R; Howson-Wells, H. C.; Jääskeläinen, A. J.; López-Labrador, F. Xavier; Maier, M.; Majumdar, M.; Midgley, S.; Mirand, A.; Morley, U.; Nordbø, Svein Arne; Oikarinen, S; Osman, H; Papa, A; Pellegrinelli, L; Piralla, A; Rabella, N; Richter, J; Smith, M; Söderlund Strand, A; Templeton, K; Vipond, B; Vuorinen, T; Williams, C; Wollants, E; Zakikhany, K; Fischer, T. K.; Harvala, H; Simmonds, P (Journal article; Peer reviewed, 2019)
      Polymerase chain reaction (PCR) detection has become the gold standard for diagnosis and typing of enterovirus (EV) and human parechovirus (HPeV) infections. Its effectiveness depends critically on using the appropriate ...
    • A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes 

      Hansen, Maren Fridtjofsen; Neckmann, Ulrike; Lavik, Liss Anne; Vold, Trine; Gilde, Bodil; Toft, Ragnhild Karlgård; Sjursen, Wenche (Journal article; Peer reviewed, 2014)
      The purpose of this study was to develop a massive parallel sequencing (MPS) workflow for diagnostic analysis of mismatch repair (MMR) genes using the GS Junior system (Roche). A pathogenic variant in one of four MMR genes, ...
    • A meta-analysis of constraint-induced movement therapy after stroke 

      Thrane, Gyrd; Friborg, Oddgeir; Anke, Audny; Indredavik, Bent (Journal article; Peer reviewed, 2014)
      Objective: To evaluate the effect of constraint-induced movement therapy in adult stroke patients and to examine the impact of time since stroke and various treatment modalities. Data sources: PubMed, EMBASE, Cochrane and ...
    • A much valued tool that also brings ethical dilemmas-a qualitative study of Norwegian midwives' experiences and views on the role of obstetric ultrasound 

      Åhman, Annika; Edvardsson, Kristina; Fagerli, Anita; Darj, Elisabeth; Holmlund, Sofia; Small, Rhonda; Mogren, Ingrid (Journal article; Peer reviewed, 2019)
      Background: Midwives are the main providers of routine antenatal care services including the routine ultrasound examination in Norway. The ultrasound examination can be perceived by expectant parents not only as a medical ...
    • A much valued tool that also brings ethical dilemmas-a qualitative study of Norwegian midwives' experiences and views on the role of obstetric ultrasound 

      Åhman, Annika; Edvardsson, Kristina; Fagerli, Anita; Darj, Elisabeth; Holmlund, Sofia; Small, Rhonda; Mogren, Ingrid (Journal article; Peer reviewed, 2019)
      Background Midwives are the main providers of routine antenatal care services including the routine ultrasound examination in Norway. The ultrasound examination can be perceived by expectant parents not only as a medical ...
    • A multi-center comparison of vO2peak trainability between interval training and moderate intensity continuous training 

      Williams, Camilla J.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Voisin, Sarah; Li, Zhixiu; Harvey, Nicholas; Croci, Ilaria; Taylor, Jenna L; Gajanand, Trishan; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Pattyn, Nele; Howden, Erin J.; Keating, Shelley E.; Bye, Anja; Stensvold, Dorthe; Wisløff, Ulrik; Papadimitriou, Ioannis; Yan, Xu; Bishop, David J.; Eynon, Nir; Coombes, Jeff S. (Journal article; Peer reviewed, 2019)
      There is heterogeneity in the observed VO2peak response to similar exercise training, and different exercise approaches produce variable degrees of exercise response (trainability). The aim of this study was to combine ...
    • A multiparameter model for non-invasive detection of hypoglycemia 

      Elvebakk, Ole; Tronstad, Christian; Birkeland, Kåre I.; Jenssen, Trond Geir; Bjørgaas, Marit Ragnhild Rokne; Gulseth, Hanne Løvdal; Kalvøy, Håvard; Høgetveit, Jan Olav; Martinsen, Ørjan Grøttem (Journal article; Peer reviewed, 2019)
      Objective: Severe hypoglycemia is the most serious acute complication for people with type 1 diabetes (T1D). Approximately 25% of people with T1D have impaired ability to recognize impending hypoglycemia, and nocturnal ...