Browsing St. Olavs hospital by Journals "Cell Reports Medicine"

Now showing items 1-2 of 2

    • Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses 

      Ladner, Jason T.; Henson, Sierra N.; Boyle, Annalee S.; Engelbrektson, Anna L.; Fink, Zane W.; Rahee, Fatima; D'ambrozio, Jonathan; Schaecher, Kurt E.; Stone, Mars; Dong, Wenjuan; Dadwal, Sanjeet; Yu, Jianhua; Caligiuri, Michael A.; Cieplak, Piotr; Bjørås, Magnar; Fenstad, Mona H.; Nordbø, Svein Arne; Kainov, Denis; Muranaka, Norihito; Chee, Mark S.; Shiryaev, Sergey A.; Altin, John A. (Peer reviewed; Journal article, 2021)
      The SARS-CoV-2 proteome shares regions of conservation with endemic human coronaviruses (CoVs), but it remains unknown to what extent these may be cross-recognized by the antibody response. Here, we study cross-reactivity ...

    • Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities 

      Aprigliano, Rossana; Aksu, Merdane Ezgi; Bradamante, Stefano; Mihaljevic, Boris; Wang, Wei; Rian, Kristin; Montaldo, Nicola Pietro; Grooms, Kayla; Martin, Sarah; Bordin, Diana Lilian; Bosshard, Matthias; Peng, Yunhui; Alexov, Emil; Skinner, Cindy; Liabakk, Nina-Beate; Sullivan, Gareth; Bjørås, Magnar; Schwartz, Charles; van Loon, Barbara (Peer reviewed; Journal article, 2021)
      Essential E3 ubiquitin ligase HUWE1 (HECT, UBA, and WWE domain containing 1) regulates key factors, such as p53. Although mutations in HUWE1 cause heterogenous neurodevelopmental X-linked intellectual disabilities (XLIDs), ...