• DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis – A narrative review from the ECNP bipolar disorders network 

      Kessing, Lars Vedel; Gonzalez-Pinto, Ana; Fagiolini, Andrea; Bechdolf, Andreas; Reif, Andreas; Yildiz, Ayşegül; Etain, Bruno; Henry, Chantal; Severus, Emanuel; Reininghaus, Eva Z.; Morken, Gunnar; Goodwin, Guy M.; Scott, Jan; Geddes, John R.; Rietschel, Marcella; Landén, Mikael; Manchia, Mirko; Bauer, Michael; Martinez-Cengotitabengoa, Monica; Andreassen, Ole Andreas; Ritter, Philipp; Kupka, Ralph; Licht, Rasmus W.; Nielsen, René E.; Schulze, Thomas G.; Hajek, Tomas; Lagerberg, Trine Vik; Bergink, Veerle; Vieta, Eduard (Peer reviewed; Journal article, 2021)
      This narrative review summarizes and discusses the implications of the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 and the upcoming International Classification of Diseases (ICD)-11 classification systems ...
    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O’Connell, Kevin; Ueland, Thor; Ahmed, Mashhood Sheikh; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John Abel; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Auten Weibell, Melissa; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2022)
      Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...
    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2021)
      Background -Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...
    • Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review 

      Reininghaus, Eva Z.; Manchia, Mirko; Dalkner, Nina; Bonkat, Nina; Squassina, Alessio; Hodl, Isabel; Vieta, Eduard; Reif, Andreas; Hajek, Tomas; Landen, Mikael; Correll, Cristoph U.; Scott, Jan; Etain, Bruno; Rietschel, Marcella; Bergink, Veerle; Martinez-Cengotitabengoa, Monica; Kessing, Lars Vedel; Fagiolini, Andrea; Bauer, Michael; Goodwin, Guy M.; Gonzalez-Pinto, Ana; Kupka, Ralph; Schulze, Thomas G.; Lagerberg, Trine Vik; Yildiz, Ayşegül; Henry, Chantal; Morken, Gunnar; Ritter, Philipp; Nieslen, Rene Ernst; Licht, Rasmus W.; Bechdolf, Andreas; Andreassen, Ole; Fellendorf, Frederike T. (Peer reviewed; Journal article, 2021)
      Bipolar disorder (BD) might be associated with higher infection rates of coronavirus disease (COVID-19) which in turn could result in worsening the clinical course and outcome. This may be due to a high prevalence of somatic ...
    • Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study 

      Engh, John; Ueland, Thor; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Wedervang-Resell, Kirsten; Weibell, Melissa; Westlye, Lars Tjelta; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole (Peer reviewed; Journal article, 2021)
      Background Immune dysfunction has been implicated in the pathogenesis of schizophrenia and other nonaffective psychosis (SCZ), bipolar spectrum disorder (BIP) and major depressive disorder (MDD). The cytokines B cell-activating ...
    • Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation 

      Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)
      Background Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ...
    • Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action 

      Manchia, Mirko; Vieta, Eduard; Smeland, Olav Bjerkehagen; Altimus, Cara; Bechdolf, Andreas; Bellivier, Frank; Bergink, Veerle; Fagiolini, Andrea; Geddes, John R.; Hajek, Tomas; Henry, Chantal; Kupka, Ralph; Lagerberg, Trine Vik; Licht, Rasmus W.; Martinez-Cengotitabengoa, Monica; Morken, Gunnar; Nielsen, René E.; Pinto, Ana Gonzalez; Reif, Andreas; Rietschel, Marcella; Ritter, Philipp; Schulze, Thomas G.; Scott, Janine Linda; Severus, Emanuel; Yildiz, Aysegul; Kessing, Lars Vedel; Bauer, Michael; Goodwin, Guy M.; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2020)
      Bipolar disorder (BD) is a major healthcare and socio-economic challenge. Despite its substantial burden on society, the research activity in BD is much smaller than its economic impact appears to demand. There is a consensus ...