• Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use 

      Liu, Ming; Jiang, Yu; Wedow, Robbee; Li, Yue; Brazel, David M.; Chen, Fang; Datta, Gargi; Davila-Velderrain, Jose; Mitchell, Amy; Skogholt, Anne Heidi; Sivertsen, Børge; Stordal, Eystein; Morken, Gunnar; Kallestad, Håvard; Heuch, Ingrid; Zwart, John-Anker; Fjukstad, Katrine Kveli; Pedersen, Linda Margareth; Johnsen, Marianne Bakke; Skrove, Marit Synnøve; Indredavik, Marit Sæbø; Drange, Ole Kristian; Bjerkeset, Ottar; Børte, Sigrid; Stensland, Synne; Choquet, Hélène; Docherty, Anna R.; Faul, Jessica D.; Foerster, Johanna R.; Fritsche, Lars; Gabrielsen, Maiken Elvestad; Gordon, Scott D.; Haessler, Jeffrey; Hottenga, Jouke-Jan; Huang, Hongyan; Jang, Seon-Kyeong; Jansen, Philip R.; Ling, Yueh; Mägi, Reedik; Matoba, Nana; McMahon, George; Mulas, Antonella; Orrú, Valeria; Palviainen, Teemu; Pandit, Anita; Reginsson, Gunnar W.; Smith, Jennifer A.; Taylor, Amy E.; Turman, Constance; Willemsen, Gonneke; Young, Hannah; Young, Kendra A.; Zajac, Gregory J.M.; Zhao, Wei; Zhou, Wei; Björnsdóttir, Gyda Thora; Boardman, Jason D.; Boehnke, Michael; Boomsma, Dorret I.; Chen, Chu; Davies, Gareth E.; Eaton, Charles B.; Winsvold, Bendik K S; Hveem, Kristian; Vrieze, Scott (Journal article; Peer reviewed, 2019)
      Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders1. They are heritable2,3 and etiologically related4,5 behaviors that have been resistant to gene discovery ...
    • Can consumer grade activity devices replace research grade actiwatches in youth mental health settings? 

      Scott, Janine Linda; Grierson, Ashlee; Lillian, Gehue; Kallestad, Håvard; MacMillan, Iain; Hickie, Ian (Peer reviewed; Journal article, 2019)
      Mental health services increasingly recognize the benefits of monitoring sleep and activity patterns in youth. Objective, ecological monitoring via research grade actiwatches is valid, but an emerging literature suggests ...
    • Contact-free radar recordings of body movement can reflect ultradian dynamics of sleep 

      Heglum, Hanne Siri Amdahl; Drews, Henning Johannes; Kallestad, Håvard; Vethe, Daniel; Langsrud, Knut; Sand, Trond; Engstrøm, Morten (Peer reviewed; Journal article, 2022)
      This work aimed to evaluate if a contact-free radar sensor can be used to observe ultradian patterns in sleep physiology, by way of a data processing tool known as Locomotor Inactivity During Sleep (LIDS). LIDS was designed ...
    • Digital cognitive behaviour therapy for insomnia (dCBT-I): Chronotype moderation on intervention outcomes 

      Faaland, Patrick; Vedaa, Øystein; Langsrud, Knut; Sivertsen, Børge; Lydersen, Stian; Vestergaard, Cecilie Lund; Kjørstad, Kaia; Vethe, Daniel; Ritterband, Lee M.; Harvey, Allison G.; Stiles, Tore C; Scott, Janine Linda; Kallestad, Håvard (Peer reviewed; Journal article, 2022)
      Using data from 1721 participants in a community-based randomized control trial of digital cognitive behavioural therapy for insomnia compared with patient education, we employed linear mixed modelling analyses to examine ...
    • Digital cognitive behaviour therapy for insomnia in individuals with self-reported insomnia and chronic fatigue: A secondary analysis of a large scale randomized controlled trial 

      Ramfjord, Lina Stålesen; Faaland, Patrick Michael Palmelund; Scott, Janine Linda; Saksvik, Simen Berg; Lydersen, Stian; Vedaa, Øystein; Kahn, Nikolaj; Langsrud, Knut; Stiles, Tore Charles; Ritterband, Lee M.; Harvey, Allison G.; Sivertsen, Børge; Kallestad, Håvard (Peer reviewed; Journal article, 2023)
      Insomnia is associated with fatigue, but it is unclear whether response to cognitive behaviour therapy for insomnia is altered in individuals with co-occurring symptoms of insomnia and chronic fatigue. This is a secondary ...
    • Digital cognitive-behavioural therapy for insomnia compared with digital patient education about insomnia in individuals referred to secondary mental health services in Norway: Protocol for a multicentre randomised controlled trial 

      Kallestad, Håvard; Saksvik, Simen Berg; Vedaa, Øystein; Langsrud, Knut; Morken, Gunnar; Lydersen, Stian; Simpson, Melanie Rae; Dørheim, Signe Karen; Holmøy, Bjørn; Germans Selvik, Sara; Hagen, Kristen; Stiles, Tore C; Harvey, Allison G.; Ritterband, Lee M.; Sivertsen, Børge; Scott, Janine Linda (Peer reviewed; Journal article, 2021)
      Introduction Insomnia is highly prevalent in outpatients receiving treatment for mental disorders. Cognitive–behavioural therapy for insomnia (CBT-I) is a recommended first-line intervention. However, access is limited and ...
    • Distinguishing sleep from wake with a radar sensor: A contact-free real-time sleep monitor 

      Heglum, Hanne Siri Amdahl; Kallestad, Håvard; Vethe, Daniel; Langsrud, Knut; Sand, Trond; Engstrøm, Morten (Journal article; Peer reviewed, 2021)
      This work aimed to evaluate whether a radar sensor can distinguish sleep from wakefulness in real time. The sensor detects body movements without direct physical contact with the subject and can be embedded in the roof of ...
    • Dysfunctional beliefs and attitudes about sleep (DBAS) mediate outcomes in dCBT-I on psychological distress, fatigue, and insomnia severity 

      Faaland, Patrick; Vedaa, Øystein; Langsrud, Knut; Sivertsen, Børge; Lydersen, Stian; Saksvik, Simen Berg; Vestergaard, Cecilie Lund; Kjørstad, Kaia; Vethe, Daniel; Ritterband, Lee M.; Harvey, Allison G.; Stiles, Tore Charles; Scott, Janine Linda; Kallestad, Håvard (Peer reviewed; Journal article, 2023)
      Objective/background Digital cognitive behavioral therapy for insomnia (dCBT-I) improves several sleep and health outcomes in individuals with insomnia. This study investigates whether changes in Dysfunctional Beliefs and ...
    • The effect of sleep-wake intraindividual variability in digital cognitive behavioral therapy for insomnia: a mediation analysis of a large-scale RCT 

      Vestergaard, Cecilie Lund; Vedaa, Øystein; Simpson, Melanie Rae; Faaland, Patrick; Vethe, Daniel; Kjørstad, Kaia; Langsrud, Knut; Ritterband, Lee M; Sivertsen, Børge; Stiles, Tore C; Scott, Jan; Kallestad, Håvard (Peer reviewed; Journal article, 2021)
      Study Objectives Digital cognitive behavioral therapy for insomnia (dCBT-I) is an effective treatment for insomnia. However, less is known about mediators of its benefits. The aim of the present study was to test if ...
    • Effects of digital cognitive behavioural therapy for insomnia on insomnia severity: a large-scale randomised controlled trial 

      Vedaa, Øystein; Kallestad, Håvard; Scott, Janine Linda; Smith, Otto Robert Frans; Pallesen, Ståle; Morken, Gunnar; Langsrud, Knut; Gehrman, Philip; Thorndike, Frances P.; Ritterband, Lee M.; Harvey, Allison G.; Stiles, Tore C; Sivertsen, Børge (Peer reviewed; Journal article, 2020)
      Background Although several large-scale randomised controlled trials have shown the efficacy of digital cognitive behavioural therapy for insomnia (dCBT-I), there is a need to validate widespread dissemination of dCBT-I ...
    • Evening light environments can be designed to consolidate and increase the duration of REM-sleep 

      Vethe, Daniel; Drews, Henning Johannes; Scott, Janine Linda; Engstrøm, Morten; Heglum, Hanne Siri Amdahl; Grønli, Janne; Wisor, J.P.; Sand, Trond; Lydersen, Stian; Kjørstad, Kaia; Faaland, Patrick; Vestergaard, Cecilie Lund; Langsrud, Knut; Kallestad, Håvard (Peer reviewed; Journal article, 2022)
      Evening exposure to short-wavelength light has disruptive effects on circadian rhythms and sleep. These effects can be mitigated by blocking short-wavelength (blue) frequencies, which has led to the development of evening ...
    • High neuroticism is associated with reduced negative affect following sleep deprivation 

      Saksvik-Lehouillier, Ingvild; Langvik, Eva; Saksvik, Simen Berg; Kallestad, Håvard; Follesø, Hanna Størksen; Austad, Sigrun Borgen; Dahlberg, Johanna; Ringen, Heidi; Tanum, Tiril Kristine; Sørengaard, Torhild Anita; Karlsen, Håvard Rudi; Smedbøl, Trine; Olsen, Alexander (Peer reviewed; Journal article, 2021)
      The aim was to investigate how neuroticism moderates the affective consequences of personalized mild-moderate partial sleep deprivation. A total of 52 healthy subjects aged 18–35 years completed the NEO PI-3 at baseline, ...
    • Long-Term Effects of an Unguided Online Cognitive Behavioral Therapy for Chronic Insomnia 

      Vedaa, Øystein; Hagatun, Susanne; Kallestad, Håvard; Pallesen, Ståle; Smith, Otto Robert Frans; Thorndike, Frances P; Ritterband, Lee M.; Sivertsen, Børge (Journal article; Peer reviewed, 2019)
      STUDY OBJECTIVES: The aim of this study was to test the efficacy of fully automated Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) 18 months after the intervention period on sleep, daytime functioning, ...
    • Mild to moderate partial sleep deprivation is associated with increased impulsivity and decreased positive affect in young adults 

      Saksvik-Lehouillier, Ingvild; Saksvik, Simen Berg; Dahlberg, Berit Johanna; Tanum, Tiril Kristine; Ringen, Heidi; Karlsen, Håvard Rudi; Smedbøl, Trine; Sørengaard, Torhild Anita; Stople, Mailen; Kallestad, Håvard; Olsen, Alexander (Peer reviewed; Journal article, 2020)
      The effects of mild–moderate partial sleep deprivation on affective and cognitive functioning were evaluated in a naturalistic home environment, mimicking short sleep typically caused by demands from work or society. A ...
    • Mode of delivery of Cognitive Behavioral Therapy for Insomnia: a randomized controlled non-inferiority trial of digital and face-to-face therapy 

      Kallestad, Håvard; Scott, Janine Linda; Vedaa, Øystein; Lydersen, Stian; Vethe, Daniel; Morken, Gunnar; Stiles, Tore C; Sivertsen, Børge; Langsrud, Knut (Peer reviewed; Journal article, 2021)
      Study Objectives Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I) has demonstrated efficacy in reducing insomnia severity in self-referred and community samples. It is unknown, however, how dCBT-I compares to ...
    • Poorer sleep health is associated with altered brain activation during cognitive control processing in healthy adults 

      Smevik, Hanne; Habli, Sarah; Saksvik, Simen Berg; Kliem, Elisabeth; Evensmoen, Hallvard Røe; Conde, Virginia; Petroni, Agustin; Asarnow, Robert F.; Dennis, Emily L.; Eikenes, Live; Kallestad, Håvard; Sand, Trond Halfdan; Thompson, Paul M.; Saksvik-Lehouillier, Ingvild; Håberg, Asta; Olsen, Alexander (Peer reviewed; Journal article, 2023)
      This study investigated how proactive and reactive cognitive control processing in the brain was associated with habitual sleep health. BOLD fMRI data were acquired from 81 healthy adults with normal sleep (41 females, age ...
    • The prevalence and stability of sleep-wake disturbance and fatigue throughout the first year after mild traumatic brain injury 

      Saksvik, Simen Berg; Karaliute, Migle; Kallestad, Håvard; Follestad, Turid; Asarnow, Robert F.; Vik, Anne; Håberg, Asta; Skandsen, Toril; Olsen, Alexander (Peer reviewed; Journal article, 2020)
      In this prospective, longitudinal study, we aimed to determine the prevalence and stability of sleep-wake disturbance (SWD) and fatigue in a large representative sample of patients (Trondheim mild traumatic brain injury ...
    • Sleep and work functioning in nurses undertaking inpatient shifts in a blue-depleted light environment 

      Kjørstad, Kaia; Faaland, Patrick; Sivertsen, Børge; Kallestad, Håvard; Langsrud, Knut; Vethe, Daniel; Vestergaard, Cecilie Lund; Harris, Anette Kristoffersen; Pallesen, Ståle; Scott, Jan; Vedaa, Øystein (Peer reviewed; Journal article, 2022)
      Background Blue-depleted light environments (BDLEs) may result in beneficial health outcomes for hospital inpatients in some cases. However, less is known about the effects on hospital staff working shifts. This study ...
    • Using network intervention analysis to explore associations between participant expectations of and difficulties with cognitive behavioural therapy for insomnia and clinical outcome: A proof of principle study 

      Scott, Janine Linda; Vedaa, Øystein; Sivertsen, Børge; Langsrud, Knut; Kallestad, Håvard (Peer reviewed; Journal article, 2022)
      Background Research about predictors of response to cognitive behaviour therapy for insomnia (CBT-I) is ongoing. We examined any whether pre-intervention expectations or post-intervention appraisals of difficulties in ...