• Artificial intelligence for prostate MRI: open datasets, available applications, and grand challenges 

      Sunoqrot, Mohammed R. S.; Saha, Anindo; Hosseinzadeh, Matin; Elschot, Mattijs; Huisman, Henkjan J (Peer reviewed; Journal article, 2022)
      Artificial intelligence (AI) for prostate magnetic resonance imaging (MRI) is starting to play a clinical role for prostate cancer (PCa) patients. AI-assisted reading is feasible, allowing workflow reduction. A total of ...
    • Artificial intelligence for prostate MRI: open datasets, available applications, and grand challenges 

      Sunoqrot, Mohammed R. S.; Saha, Anindo; Hosseinzadeh, Matin; Elschot, Mattijs; Huisman, Henkjan J (Peer reviewed; Journal article, 2022)
      Artificial intelligence (AI) for prostate magnetic resonance imaging (MRI) is starting to play a clinical role for prostate cancer (PCa) patients. AI-assisted reading is feasible, allowing workflow reduction. A total of ...
    • Cholesterol crystals and NLRP3 mediated inflammation in the uterine wall decidua in normal and preeclamptic pregnancies 

      Silva, Gabriela; Gierman, Lobke; Rakner, Johanne Johnsen; Stødle, Guro; Mundal, Siv Boon; Thaning, Astrid Josefin; Sporsheim, Bjørnar; Elschot, Mattijs; Collett, Karin; Bjørge, Line; Aune, Marie Hjelmseth; Thomsen, Liv Cecilie Vestrheim; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2020)
      Preeclampsia is a hypertensive and inflammatory pregnancy disorder associated with cholesterol accumulation and inflammation at the maternal-fetal interface. Preeclampsia can be complicated with fetal growth restriction ...
    • A comparison of Generative Adversarial Networks for automated prostate cancer detection on T2-weighted MRI 

      Patsanis, Alexandros; Sunoqrot, Mohammed R. S.; Langørgen, Sverre; Wang, Hao; Selnæs, Kirsten Margrete; Bertilsson, Maria Helena; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2023)
      Generative Adversarial Networks (GANs) have shown potential in medical imaging. In this study, several previously developed GANs were investigated for prostate cancer (PCa) detection on T2-weighted (T2W) magnetic resonance ...
    • Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies 

      Rakner, Johanne Johnsen; Silva, Gabriela; Mundal, Siv Boon; Thaning, Astrid Josefin; Elschot, Mattijs; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Gierman, Lobke; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2021)
      Introduction: Inflammation is a normal physiological process that increases to harmful levels in preeclampsia. It affects the interaction between maternal immune cells and fetal trophoblasts at both sites of the maternal-fetal ...
    • Detection of recurrent prostate cancer with 18F-Fluciclovine PET/MRI 

      Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Johansen, Håkon; Steen, Per Arvid; Langørgen, Sverre; Aksnessæther, Bjørg Yksnøy; Indrebø, Gunnar; Sjøbakk, Torill Eidhammer; Tessem, May-Britt; Moestue, Siver Andreas; Knobel, Heidi; Tandstad, Torgrim; Bertilsson, Helena; Solberg, Arne; Bathen, Tone Frost (Peer reviewed; Journal article, 2020)
      Objective: Simultaneous PET/MRI combines soft-tissue contrast of MRI with high molecular sensitivity of PET in one session. The aim of this prospective study was to evaluate detection rates of recurrent prostate cancer by ...
    • Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction 

      Mundal, Siv Boon; Rakner, Johanne Johnsen; Silva, Gabriela; Gierman, Lobke; Austdal, Marie; Basnet, Purusotam; Elschot, Mattijs; Bakke, Siril Skaret; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Moses, Eric; Acharya, Ganesh; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2022)
      Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are ...
    • Pelvic PET/MR attenuation correction in the image space using deep learning 

      Abrahamsen, Bendik Skarre; Knudtsen, Ingerid Søberg Skjei; Eikenes, Live; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2023)
    • Pseudo-T2 mapping for normalization of T2-weighted prostate MRI 

      Sørland, Kaia Ingerdatter; Sunoqrot, Mohammed R. S.; Sandsmark, Elise; Langørgen, Sverre; Bertilsson, Helena; Trimble, Christopher George; Lin, Gigin; Selnæs, Kirsten Margrete; Goa, Pål Erik; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2022)
      Objective Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for quantitative analysis of multicenter data. AutoRef is an automated dual-reference ...
    • A Quality Control System for Automated Prostate Segmentation on T2-Weighted MRI 

      Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Nketiah, Gabriel Addio; Zavala-Romero, Olmo; Stoyanova, Radka; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2020)
      Computer-aided detection and diagnosis (CAD) systems have the potential to improve robustness and efficiency compared to traditional radiological reading of magnetic resonance imaging (MRI). Fully automated segmentation ...
    • Reducing prostate biopsies and magnetic resonance imaging with prostate cancer risk stratification 

      Davik, Petter; Remmers, Sebastiaan; Elschot, Mattijs; Roobol, Monique J; Bathen, Tone Frost; Bertilsson, Helena (Journal article; Peer reviewed, 2022)
    • Relative Enhanced Diffusivity in Prostate Cancer: Protocol Optimization and Diagnostic Potential 

      Billdal, Daniel Chen; While, Peter Thomas; Selnæs, Kirsten Margrete; Sunoqrot, Mohammed; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2019)
      Background Relative enhanced diffusivity (RED) is a potential biomarker for indirectly measuring perfusion in tissue using diffusion‐weighted magnetic resonance imaging (MRI) with 3 b values. Purpose To optimize the RED ...
    • The Reproducibility of Deep Learning-Based Segmentation of the Prostate Gland and Zones on T2-Weighted MR Images 

      Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2021)
      Volume of interest segmentation is an essential step in computer-aided detection and diagnosis (CAD) systems. Deep learning (DL)-based methods provide good performance for prostate segmentation, but little is known about ...
    • Simultaneous 18F-fluciclovine Positron Emission Tomography and Magnetic Resonance Spectroscopic Imaging of Prostate Cancer 

      Esmaeili, Morteza; Tayari, Nassim; Scheenen, Tom WJ; Elschot, Mattijs; Sandsmark, Elise; Bertilsson, Helena; Heerschap, Arend; Selnæs, Kirsten Margrete; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)
      Purpose: To investigate the associations of metabolite levels derived from magnetic resonance spectroscopic imaging (MRSI) and 18F-fluciclovine positron emission tomography (PET) with prostate tissue characteristics. Methods: ...
    • TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies 

      Gierman, Lobke; Silva, Gabriela; Pervaiz, Zahra; Rakner, Johanne Johnsen; Mundal, Siv Boon; Thaning, Astrid J.; Nervik, Ingunn; Elschot, Mattijs; Mathew, Seema; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2020)
      Inflammation and oxidative stress at the maternal‐fetal interface characterize the placental dysfunction that underlies the pregnancy disorder preeclampsia. Specialized fetal trophoblasts directly interact with leukocytes ...
    • Utility of T2-weighted MRI texture analysis in assessment of peripheral zone prostate cancer aggressiveness: a single-arm, multicenter study 

      Nketiah, Gabriel Addio; Elschot, Mattijs; Scheenen, Tom W.J.; Maas, Marnix C.; Bathen, Tone Frost; Selnæs, Kirsten Margrete (Peer reviewed; Journal article, 2021)
      T2-weighted (T2W) MRI provides high spatial resolution and tissue-specific contrast, but it is predominantly used for qualitative evaluation of prostate anatomy and anomalies. This retrospective multicenter study evaluated ...