Blar i St. Olavs hospital på tidsskrift "iScience"
Viser treff 1-4 av 4
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The genes controlling normal function of citrate and spermine secretion are lost in aggressive prostate cancer and prostate model systems
(Peer reviewed; Journal article, 2022)High secretion of the metabolites citrate and spermine is a unique hallmark for normal prostate epithelial cells, and is reduced in aggressive prostate cancer. However, the identity of the genes controlling this biological ... -
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
(Journal article; Peer reviewed, 2021)Interleukin-32 (IL-32) is a nonclassical cytokine expressed in cancers, inflammatory diseases, and infections. Its expression is regulated by two different oxygen sensing systems; HIF1α and cysteamine dioxygenase (ADO), ... -
Neural signaling modulates metabolism of gastric cancer
(Peer reviewed; Journal article, 2021)Tumors comprise cancer cells and the associated stromal and immune/inflammatory cells, i.e., tumor microenvironment (TME). Here, we identify a metabolic signature of human and mouse model of gastric cancer and show that ... -
sMETASeq: combined profiling of microbiota and host small RNAs
(Peer reviewed; Journal article, 2020)Understanding microbial communities' roles in human health and disease requires methods that accurately characterize the microbial composition and their activity and effects within human biological samples. We present ...