Blar i St. Olavs hospital på tidsskrift "Frontiers in Immunology"
Viser treff 1-11 av 11
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Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?
(Peer reviewed; Journal article, 2021)In this review article we discuss the role of the memory T cells in multiple myeloma (MM) and how they may influence immune responses in patients that received immunomodulating drugs and check point therapy -
Cholesterol crystals and NLRP3 mediated inflammation in the uterine wall decidua in normal and preeclamptic pregnancies
(Peer reviewed; Journal article, 2020)Preeclampsia is a hypertensive and inflammatory pregnancy disorder associated with cholesterol accumulation and inflammation at the maternal-fetal interface. Preeclampsia can be complicated with fetal growth restriction ... -
Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids
(Journal article; Peer reviewed, 2023) -
Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond
(Peer reviewed; Journal article, 2021)Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands. We performed cytokine profiling of 1149 longitudinal serum ... -
Femoral nailing associated with bone marrow emboli in pigs induced a specific increase in blood IL-6 and broad inflammatory responses in the heart and lungs
(Journal article; Peer reviewed, 2024)Introduction: Bone marrow embolization may complicate orthopedic surgery, potentially causing fat embolism syndrome. The inflammatory potential of bone marrow emboli is unclear. We aimed to investigate the inflammatory ... -
Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN
(Peer reviewed; Journal article, 2021)The innate immune and host-protective responses to viruses, such as the airway pathogen human metapneumovirus (HMPV), depend on interferons (IFNs) that is induced through TANK-binding kinase 1 (TBK1) and IFN regulatory ... -
IL-32 is induced by activation of toll-like receptors in multiple myeloma cells
(Peer reviewed; Journal article, 2023)Multiple myeloma (MM) is a hematological cancer characterized by accumulation of malignant plasma cells in the bone marrow. The patients are immune suppressed and suffer from recurrent and chronic infections. Interleukin-32 ... -
Non-coding RNAs in human breast milk: A systematic review
(Peer reviewed; Journal article, 2021)Breast milk is the primary source of nutrition and hydration for the newborn infant but also plays an important role in the child’s first immune defense. Additionally, several breast milk factors have been implicated in ... -
Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids
(Peer reviewed; Journal article, 2023)Background: The epithelium in the colonic mucosa is implicated in the pathophysiology of various diseases, including inflammatory bowel diseases and colorectal cancer. Intestinal epithelial organoids from the colon (colonoids) ... -
Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium
(Peer reviewed; Journal article, 2022)Major Histocompatibility Complex (MHC)-I and -II genes are upregulated in intestinal epithelial cells (IECs) during active inflammatory bowel diseases (IBD), but little is known about how IBD-relevant pro-inflammatory ... -
Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood
(Journal article; Peer reviewed, 2023)