Blar i St. Olavs hospital på forfatter "Cappola, Anne R."

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    • GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer 

      Zhou, Wei; Brumpton, Ben Michael; Kabil, Omer; Gudmundsson, Julius; Thorleifsson, Gudmar; Weinstock, Joshua; Zawistowski, Matthew; Nielsen, Jonas Bille; Chaker, Layal; Medici, Marco; Teumer, Alexander; Naitza, Silvia; Sanna, Serena; Schultheiss, Ulla T.; Cappola, Anne R.; Karjalainen, Juha; Kurki, Mitja I.; Oneka, Morgan; Taylor, Peter; Fritsche, Lars; Graham, Sarah E.; Wolford, Brooke N.; Overton, William; Rasheed, Humaira; Bordal, Eirin Haug; Gabrielsen, Maiken Elvestad; Skogholt, Anne Heidi; Surakka, Ida; Davey Smith, George; Pandit, Anita; Roychowdhury, Tanmoy; Hornsby, Whitney; Jonasson, Jon G.; Senter, Leigha; Liyanarachchi, Sandya; Ringel, Matthew D.; Xu, Li; Kiemeney, Lambertus A.; He, Huiling; Netea-Maier, Romana; Mayordomo, Jose; Plantinga, Theo S.; Hrafnkelsson, Jon; Hjartarson, Hannes; Sturgis, Erich M.; Palotie, Aarno; Daly, Mark J.; Citterio, Cintia E.; Arvan, Peter; Brummett, Chad M.; Boehnke, Michael; de la Chapelle, Albert; Stefansson, Kari; Hveem, Kristian; Willer, Cristen J.; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2020)
      Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic markers in up to ...

    • Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies 

      Syrogiannouli, Lamprini; Wildisen, Lea; Meuwese, Christiaan; Bauer, Douglas C.; Cappola, Anne R.; Gussekloo, Jacobijn; den Elzen, Wendy P. J.; Trompet, Stella; Westendorp, Rudi G. J.; Jukema, J. Wouter; Ferrucci, Luigi; Ceresini, Graziano; Åsvold, Bjørn Olav; Chaker, Layal; Peeters, Robin P.; Imaizumi, Misa; Ohishi, Waka; Vaes, Bert; Völzke, Henry; Sgarbi, Josè A.; Walsh, John P.; Dullaart, Robin P. F.; Bakker, Stephan J. L.; Iacoviello, Massimo; Rodondi, Nicolas; Del Giovane, Cinzia (Peer reviewed; Journal article, 2022)
      Background: In non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the ...

    • An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms 

      Wildisen, Lea; Del Giovane, Cinzia; Moutzouri, Elisavet; Beglinger, Shanthi; Syrogiannouli, Lamprini; Collet, Tinh-Hai; Cappola, Anne R.; Åsvold, Bjørn Olav; Bakker, Stephan J.L.; Yeap, Bu B.; Almeida, Osvaldo P.; Ceresini, Graziano; Dullaart, Robin P. F.; Ferrucci, Luigi; Grabe, Hans J.; Jukema, J. Wouter; Nauck, Matthias; Trompet, Stella; Völzke, Henry; Westendorp, Rudi G.J.; Gussekloo, Jacobijn; Klöppel, Stefan; Aujesky, Drahomir; Bauer, Douglas C.; Peeters, Robin P.; Feller, Martin; Rodondi, Nicolas (Peer reviewed; Journal article, 2020)
      In subclinical hypothyroidism, the presence of depressive symptoms is often a reason for starting levothyroxine treatment. However, data are conflicting on the association between subclinical thyroid dysfunction and ...

    • Low thyroid function is not associated with an accelerated deterioration in renal function 

      Meuwese, Christiaan L.; van Diepen, Merel; Cappola, Anne R.; Sarnak, Mark J.; Shlipak, Michael G.; Bauer, Douglas C.; Fried, Linda P.; Iacoviello, Massimo; Vaes, Bert; Degryse, Jean; Khaw, Kay-Tee; Luben, Robert N.; Åsvold, Bjørn Olav; Bjøro, Trine; Vatten, Lars Johan; de Craen, Anton J.M.; Trompet, Stella; Iervasi, Giorgio; Molinaro, Sabrina; Ceresini, Graziano; Ferrucci, Luigi; Dullaart, Robin P.F.; Bakker, Stephan J.L.; Jukema, J. Wouter; Kearney, Patricia M.; Stott, David J.; Peeters, Robin P.; Franco, Oscar H.; Völzke, Henry; Walsh, John P.; Bremner, Alexandra; Sgarbi, José A.; Maciel, Rui M.B.; Imaizumi, Misa; Ohishi, Waka; Dekker, Friedo W.; Rodondi, Nicolas; Gussekloo, Jacobijn; den Elzen, Wendy P.J. (Peer reviewed; Journal article, 2019)
      Background Chronic kidney disease (CKD) is frequently accompanied by thyroid hormone dysfunction. It is currently unclear whether these alterations are the cause or consequence of CKD. This study aimed at studying the ...

    • Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies 

      Wildisen, Lea; Moutzouri, Elisavet; Beglinger, Shanthi; Syrogiannouli, Lamprini; Cappola, Anne R.; Åsvold, Bjørn Olav; Bakker, Stephan JL; Ceresini, Graziano; Dullaart, Robin P.F.; Ferrucci, Luigi; Grabe, Hans; Jukema, J Wouter; Nauck, Matthias; Trompet, Stella; Völzke, Henry; Westendorp, Rudi G.J.; Gussekloo, Jacobijn; Peeters, Robin P.; Kloppel, Stefan; Aujesky, Drahomir; Bauer, Douglas C.; Rodondi, Nicolas; Del Giovane, Cinzia; Feller, Martin (Journal article; Peer reviewed, 2019)
      IntroductionProspective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms have yielded conflicting findings, possibly because of differences in age, sex, thyroid-stimulating ...