Browsing St. Olavs hospital by Title
Now showing items 850-869 of 1050
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Safety of thalidomide in newly diagnosed elderly myeloma patients: a meta-analysis of data from individual patients in six randomized trials
(Journal article; Peer reviewed, 2013)Treatment with melphalan-prednisone-thalidomide improves the outcome of patients with multiple myeloma and is now considered a standard of care for patients not eligible for transplantation. However, this treatment is a ... -
Samspillskvalitet mellom ansatte og små barn (1-3 år) i norske barnehager
(Journal article; Peer reviewed, 2019)Det er stor enighet om at samspillskvalitet svært viktig for små barn, men det foreligger få studier fra norske barnehager (vuggestuer og dagpleie) der dette er undersøkt på en systematisk måte. Denne artikkelen er basert ... -
A scoping review describes methods used to identify, prioritize and display gaps in health research
(Peer reviewed; Journal article, 2019)Background and Objectives Different methods to examine research gaps have been described, but there are still no standard methods for identifying, prioritizing, or reporting research gaps. This study aimed to describe ... -
Screening for frailty among older patients with cancer using blood biomarkers of inflammation
(Peer reviewed; Journal article, 2018)As frailty is associated with inflammation, biomarkers of inflammation may represent objective measures that could facilitate the identification of frailty. Glasgow prognostic score (GPS), combines C-reactive protein (CRP) ... -
Seasonality in pain, sleep and mental distress in patients with chronic musculoskeletal pain at latitude 69° N
(Peer reviewed; Journal article, 2020)Seasonality is evident in several aspects of human health and behavior, whereas seasonality in chronic pain is less well studied. We examined seasonal variation in pain severity and pain dissemination, as well as in ... -
Second Cancers in Patients With Locally Advanced Prostate Cancer Randomized to Lifelong Endocrine Treatment With or Without Radical Radiation Therapy: Long-Term Follow-up of the Scandinavian Prostate Cancer Group-7 Trial
(Peer reviewed; Journal article, 2019)Background Curative radiation therapy (RT) constitutes a cornerstone in prostate cancer (PC) treatment. We present long-term follow-up estimates for second cancer (SC) risk and overall survival (OS) in patients randomized ... -
Second cancers in radically treated Norwegian prostate cancer patients
(Journal article; Peer reviewed, 2019)Introduction: The aim of this registry-based cohort study was to estimate second cancer (SC) risk following radical prostate cancer (PC) treatment and evaluate if the risk was influenced by radiotherapy. Materials and ... -
Secreted wnt antagonists in scrub typhus
(Peer reviewed; Journal article, 2021)Background The mechanisms that control local and systemic inflammation in scrub typhus have only been partially elucidated. The wingless (Wnt) signaling pathways are emerging as important regulators of inflammation and ... -
Seizure-like events leading to hospital referrals in infants: A retrospective population-based study
(Peer reviewed; Journal article, 2020)Aim: To identify the aetiology and outcome of seizure-like events leading to hospital referrals in infants and to identify early predictors of epilepsy and delayed neurodevelopment. Methods: This Norwegian population-based ... -
Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
(Peer reviewed; Journal article, 2020)Extracorporeal photopheresis (ECP), a modality that exposes isolated leukocytes to the photosensitizer 8-methoxypsoralen (8-MOP) and ultraviolet-A (UV-A) light, is used to treat conditions such as cutaneous T-cell lymphoma ... -
Self-administered biofeedback treatment app for pediatric migraine: A randomized pilot study
(Peer reviewed; Journal article, 2020)Objective To investigate the effect size, safety, and tolerability of a therapist‐independent biofeedback treatment app among adolescent with migraine. Materials and Methods This was a prospective, 3:1 ratio randomized, ... -
Self-reported sleep quality with mandibular advancement device or continuous positive airway pressure: A randomized clinical trial on patients with mild and moderate obstructive sleep apnea
(Peer reviewed; Journal article, 2020)Study objectives To compare self-reported sleep quality, treatment compliance and respiratory event index (REI) after 4 months of treatment with mandibular advancement device (MAD) or continuous positive airway pressure ... -
Semi-automatic segmentation from intrinsically-registered 18F-FDG-PET/MRI for treatment response assessment in a breast cancer cohort: comparison to manual DCE-MRI
(Journal article; Peer reviewed, 2019)Objectives To investigate the reliability of simultaneous positron emission tomography and magnetic resonance imaging (PET/MRI)-derived biomarkers using semi-automated Gaussian mixture model (GMM) segmentation on PET ... -
Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients
(Peer reviewed; Journal article, 2021)Pneumocystis jirovecii is a threat to iatrogenically immunosuppressed individuals, a heterogeneous population at rapid growth. We assessed the ability of an in-house semiquantitative real-time PCR assay to discriminate ... -
Separating the genetics of childhood and adult obesity: a validation study of genetic scores for body mass index in adolescence and adulthood in the HUNT Study
(Peer reviewed; Journal article, 2020)From a life-course perspective, genetic and environmental factors driving childhood obesity may have a lasting inf luence on health later in life. However, how obesity trajectories vary throughout the life-course remains ... -
Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomization analysis of the HUNT study
(Journal article; Peer reviewed, 2018)We aimed to investigate potential causal associations between serum 25-hydroxyvitamin D [25(OH)D] levels and incidence of lung cancer overall and histologic types. We performed a Mendelian randomization (MR) analysis using ... -
Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: An observational study Cancer palliative care
(Peer reviewed; Journal article, 2015)Background:The feasibility and clinical implication of drug monitoring of morphine, morphine-6-glucuronide (M6G)and morphine-3-glucuronide (M3G) need further investigation. This study aimed to determine what predicts ... -
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
(Journal article; Peer reviewed, 2018)Background The IL-6 receptor antagonist tocilizumab has been shown to attenuate the proatherogenic lipoprotein a [Lp(a)] in rheumatoid arthritis. We evaluated if a single dose of tocilizumab reduced Lp(a) in patients with ... -
Severe traumatic brain injury in Norway: impact of age on outcome
(Journal article; Peer reviewed, 2013)Objective: The aim of this study was to investigate the influence of age on mortality and 3-month outcome in a Norwegian cohort of patients with severe traumatic brain injury (TBI). Methods: Norwegian residents ≥ 16 years ... -
Sexual function in long-term male lymphoma survivors after high-dose therapy with autologous stem-cell transplantation
(Journal article; Peer reviewed, 2019)Reduced sexual function may have negative implications on health related quality of life among lymphoma survivors. A national cross-sectional study among long-term lymphoma survivors after high-dose therapy with autologous ...