Browsing St. Olavs hospital by Title
Now showing items 553-572 of 1029
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Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury
(Peer reviewed; Journal article, 2020)Objective We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study Design and Setting We performed logistic regression ... -
Machine learning augmented reduced-order models for FFR-prediction
(Peer reviewed; Journal article, 2021)Computational predictions in cardiovascular medicine have largely relied on explicit models derived from physical and physiological principles. Recently, the application of artificial intelligence in cardiovascular medicine ... -
The Mammalian Cap-Specific m<sup>6</sup>Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues
(Peer reviewed; Journal article, 2020)The 5′ end of eukaryotic mRNAs is protected by the m7G-cap structure. The transcription start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at this position is further methylated at the ... -
Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding
(Peer reviewed; Journal article, 2021)Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ... -
Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report
(Peer reviewed; Journal article, 2021)Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ... -
Maternal PCOS status and metformin in pregnancy: Steroid hormones in 5–10 years old children from the PregMet randomized controlled study
(Peer reviewed; Journal article, 2021)Objective Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with potential effects on offspring both genetically and through altered intrauterine environment. Metformin, which ameliorate hormonal disturbances ... -
Maternal serum retinol, 25(OH)D and 1,25(OH)2D concentrations during pregnancy and peak bone mass and trabecular bone score in adult offspring at 26-year follow-up
(Journal article; Peer reviewed, 2019)Background Vitamin A and D deficiency is prevalent in pregnant women worldwide. Both vitamins are involved in fetal skeletal development. A positive association between maternal vitamin D levels and offspring bone mineral ... -
Maximal strength training as a physical rehabilitation for patients with substance use disorder; a randomized controlled trial
(Peer reviewed; Journal article, 2016)Background:Patients with substance use disorder (SUD) suffer from multiple health and psychosocial problems.Because poor physical capacities following an inactive lifestyle may indeed contribute to these problems, ... -
Measuring childhood maltreatment: Psychometric properties of the Norwegian version of the Maltreatment and Abuse Chronology of Exposure (MACE) scale
(Peer reviewed; Journal article, 2020)Purpose Adverse childhood experiences in sensitive periods of the developing brain render the individual at a life-long risk for a broad spectrum of aberrant health outcomes. However, there is a lack of scales for the ... -
Measuring the Cognitive Attentional Syndrome Associated with Emotional Distress: Psychometric Properties of the CAS-1
(Journal article; Peer reviewed, 2019)The self-regulatory executive function model is the basis of metacognitive therapy and proposes that psychological disorders are caused by maladaptive beliefs about thinking (metacognitive beliefs) and a perseverative ... -
Mechanisms of sporadic control failure related to the skin-electrode interface in myoelectric hand prostheses
(Journal article; Peer reviewed, 2019)Introduction This study is concerned with the control of hand prostheses based on electromyograms. As the prosthesis is moved in space, the socket and electrodes can shift on the residual limb, causing changes in the ... -
The mediating role of resilience in the relationship between perceived stress and mental health
(Peer reviewed; Journal article, 2021)The COVID-19 pandemic has created great uncertainty around the world, and due to the pandemic, nurses have been exposed to an increase in highly stressful clinical situations. This study examines the relationships between ... -
Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
(Peer reviewed; Journal article, 2020)There is a robust observational relationship between lower birthweight and higher risk of cardiometabolic disease in later life. The Developmental Origins of Health and Disease (DOHaD) hypothesis posits that adverse ... -
Mental health, academic self-efficacy and study progress among college students - The SHoT study, Norway
(Journal article; Peer reviewed, 2019)Student life can be stressful and for some students it may cause mental distress. Besides being a major public health challenge, mental distress can influence academic achievement. The main objectives of the current study ... -
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk
(Peer reviewed; Journal article, 2020)A major challenge in genetic association studies is that most associated variants fall in the non-coding part of the human genome. We searched for variants associated with bone mineral density (BMD) after enriching the ... -
Mer fysikalsk behandling og mindre kirurgi for pasienter med skuldersmerte. Virkningen av behandlingen, kunnskapshullene og veien videre.
(Peer reviewed; Journal article, 2020)Innledning: Skuldersmerte er en vanlig og ofte langvarig muskelskjelettplage. Subakromial smerte utgjør den klart største diagnostiske gruppen. I nye faglige retningslinjer frarådes den mest vanlige formen for skulderkirurgi; ... -
Metabolic adaptation is an illusion, only present when participants are in negative energy balance
(Peer reviewed; Journal article, 2020)Background The existence of metabolic adaptation, following weight loss, remains a controversial issue. To our knowledge, no study has evaluated the role of energy balance (EB) in modulating metabolic adaptation. Obj ... -
Metabolic alterations in tissues and biofluids of patients with prostate cancer
(Peer reviewed; Journal article, 2020)Altered metabolism is one of the key molecular characteristics of prostate cancer (PCa) development, and a number of studies have searched for metabolic biomarkers in patient-derived samples. Reported metabolic changes in ... -
Metabolic characterization of triple negative breast cancer
(Journal article; Peer reviewed, 2014)Background The aims of this study were to characterize the metabolite profiles of triple negative breast cancer (TNBC) and to investigate the metabolite profiles associated with human epidermal growth factor receptor-2/neu ... -
Metabolite profiling of ortho-, meta- and para-fluorofentanyl by hepatocytes and high-resolution mass spectrometry
(Peer reviewed; Journal article, 2019)New psychoactive substances are emerging on the illegal drug market. Synthetic opioids including fentanyl analogues are of special concern due to their high potency. This indicates the possibility of low drug concentrations ...