Blar i St. Olavs hospital på tittel

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    • M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis 

      Brix, Ninna; Glerup, Mia; Thiel, Steffen; Mistegaard, Clara Elbæk; Skals, Regitze Gyldenholm; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan Mary; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels (Peer reviewed; Journal article, 2021)
      Objective: Distinction on clinical grounds between acute lymphoblastic leukaemia presenting with arthropathy (ALLarthropathy) and juvenile idiopathic arthritis (JIA) is difficult, as the clinical and paraclinical signs of ...

    • Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury 

      Gravesteijn, BY; Nieboer, Daan; Ercole, Ari; Lingsma, Hester F; Nelson, David; Van Calster, Ben; Steyerberg, Ewout W; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Objective We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study Design and Setting We performed logistic regression ...

    • Machine learning augmented reduced-order models for FFR-prediction 

      Fossan, Fredrik Eikeland; Müller, Lucas O.; Sturdy, Jacob; Bråten, Anders Tjellaug; Jørgensen, Arve; Wiseth, Rune; Hellevik, Leif Rune (Peer reviewed; Journal article, 2021)
      Computational predictions in cardiovascular medicine have largely relied on explicit models derived from physical and physiological principles. Recently, the application of artificial intelligence in cardiovascular medicine ...

    • Magnetic resonance-based eye tracking using deep neural networks 

      Frey, Markus; Nau, Matthias; Doeller, Christian F. (Journal article, 2021)
      Viewing behavior provides a window into many central aspects of human cognition and health, and it is an important variable of interest or confound in many functional magnetic resonance imaging (fMRI) studies. To make eye ...

    • The Mammalian Cap-Specific m<sup>6</sup>Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues 

      Pandey, Radha Raman; Delfino, Elena; Homolka, David; Roithova, Adriana; Chen, Kuan-Ming; Li, Lingyun; Franco, Giulia; Vågbø, Cathrine Broberg; Taillebourg, Emmanuel; Fauvarque, Marie-Odile; Pillai, Ramesh S. (Peer reviewed; Journal article, 2020)
      The 5′ end of eukaryotic mRNAs is protected by the m7G-cap structure. The transcription start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at this position is further methylated at the ...

    • The management and clinical knowledge of headache disorders among general practitioners in Norway: a questionnaire survey 

      Kristoffersen, Espen Saxhaug; Faiz, Kashif Waqar; Hansen, Jakob Møller; Tronvik, Erling Andreas; Frich, Jan C; Lundqvist, Christofer; Winsvold, Bendik K S (Peer reviewed; Journal article, 2021)
      Background General practitioners (GPs) diagnose and manage a majority of headache patients seeking health care. With the aim to understand the potential for clinical improvement and educational needs, we performed a study ...

    • Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding 

      Bjørk, Marte-Helene; Kristoffersen, Espen Saxhaug; Tronvik, Erling Andreas; Nordeng, Hedvig Marie Egeland (Peer reviewed; Journal article, 2021)
      Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ...

    • Mapping the human genetic architecture of COVID-19 

      Niemi, Mari E.K.; Karjalainen, Juha; Liao, Rachel G.; Neale, Benjamin M.; Daly, Mark; Ganna, Andrea; Pathak, Gita A.; Andrews, Shea J.; Kanai, Masahiro; Veerapen, Kumar; Fernandez-Cadenas, Israel; Schulte, Eva C.; Striano, Pasquale; Afset, Jan Egil; Solligård, Erik; Damås, Jan Kristian; Risnes, Kari; Bettini, Laura Rachele; Gustad, Lise Tuset; Holter, Jan Cato; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Folseraas, Trine; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Lind, Andreas; Müller, Fredrik; Dudman, Susanne Gjeruldsen; Grimsrud, Marit Mæhle; Vadla, May Sissel; Myhre, Ronny; Kildal, Anders Benjamin; Hoff, Dag Arne Lihaug; Muller, Karl Erik; Heggelund, Lars; Bergan, Jonas; Skogen, Vegard (Journal article; Peer reviewed, 2021)
      The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ...

    • Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report 

      Murray, David L.; Puig, Noemi; Kristinsson, Sigurður Y.; Usmani, Saad; Dispenzieri, Angela; Bianchi, Giada; Kumar, Shaji; Chng, Wee Joo; Hajek, Roman; Paiva, Bruno; Waage, Anders; Rajkumar, S. Vincent; Durie, Brian (Peer reviewed; Journal article, 2021)
      Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ...

    • Maternal alcohol and drug use during pregnancy affects the motor behaviour and general movements of infants aged 3–4 months 

      Fjørtoft, Toril Larsson; Brandal, Merethe; Brubakk, Ann-Mari; Adde, Lars; Ustad, T.; Vågen, Randi Tynes; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2020)
      Background Exposure of alcohol and/or other addictive drugs in pregnancy is a documented risk factor for later neurological impairment. Aims The aim of the study was to determine whether infants suffering from prenatal ...

    • Maternal PCOS status and metformin in pregnancy: Steroid hormones in 5–10 years old children from the PregMet randomized controlled study 

      Hanem, Liv Guro Engen; Salvesen, Øyvind; Madsen, Andre; Sagen, Jørn Vegard; Mellgren, Gunnar; Juliusson, Petur Benedikt; Carlsen, Sven Magnus; Vanky, Eszter; Ødegård, Rønnaug (Peer reviewed; Journal article, 2021)
      Objective Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with potential effects on offspring both genetically and through altered intrauterine environment. Metformin, which ameliorate hormonal disturbances ...

    • Maternal serum retinol, 25(OH)D and 1,25(OH)2D concentrations during pregnancy and peak bone mass and trabecular bone score in adult offspring at 26-year follow-up 

      Balasuriya, Chandima Nirupa Dilruks; Larose, Tricia L; Mosti, Mats Peder; Evensen, Kari Anne Indredavik; Jacobsen, Geir Wenberg; Thorsby, Per Medbøe; Stunes, Astrid Kamilla; Syversen, Unni (Journal article; Peer reviewed, 2019)
      Background Vitamin A and D deficiency is prevalent in pregnant women worldwide. Both vitamins are involved in fetal skeletal development. A positive association between maternal vitamin D levels and offspring bone mineral ...

    • Maximal strength training as a physical rehabilitation for patients with substance use disorder; a randomized controlled trial 

      Unhjem, Runar Jakobsen; Flemmen, Grete; Hoff, Jan; Wang, Eivind (Peer reviewed; Journal article, 2016)
      Background:Patients with substance use disorder (SUD) suffer from multiple health and psychosocial problems.Because poor physical capacities following an inactive lifestyle may indeed contribute to these problems, ...

    • Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies 

      Melvold, Katrine; Giliberto, Mariaserena; Karlsen, Linda; Ayuda-Duran, Maria del Pilar; Hanes, Robert; Holien, Toril; Enserink, Jorrit; Brown, Jennifer R.; Tjønnfjord, Geir Erland; Tasken, Kjetil; Skånland, Sigrid Strand (Peer reviewed; Journal article, 2021)
      Most patients with chronic lymphocytic leukemia (CLL) initially respond to targeted therapies, but eventually relapse and develop resistance. Novel treatment strategies are therefore needed to improve patient outcomes. ...

    • Measuring childhood maltreatment: Psychometric properties of the Norwegian version of the Maltreatment and Abuse Chronology of Exposure (MACE) scale 

      Fosse, Roar; Skjelstad, Dag Vegard; Schalinski, Inga; Thekkumthala, Dorothea; Elbert, Thomas; Aanondsen, Chris Margaret; Greger, Hanne Klæboe; Jozefiak, Thomas (Peer reviewed; Journal article, 2020)
      Purpose Adverse childhood experiences in sensitive periods of the developing brain render the individual at a life-long risk for a broad spectrum of aberrant health outcomes. However, there is a lack of scales for the ...

    • Measuring the Cognitive Attentional Syndrome Associated with Emotional Distress: Psychometric Properties of the CAS-1 

      Nordahl, Henrik; Wells, Adrian (Journal article; Peer reviewed, 2019)
      The self-regulatory executive function model is the basis of metacognitive therapy and proposes that psychological disorders are caused by maladaptive beliefs about thinking (metacognitive beliefs) and a perseverative ...

    • Mechanisms of sporadic control failure related to the skin-electrode interface in myoelectric hand prostheses 

      Stavdahl, Øyvind; Terje, Mugaas; Ottermo, Maria Vatshaug; Magne, Tordis; Kyberd, Peter Joseph (Journal article; Peer reviewed, 2019)
      Introduction This study is concerned with the control of hand prostheses based on electromyograms. As the prosthesis is moved in space, the socket and electrodes can shift on the residual limb, causing changes in the ...

    • The mediating role of resilience in the relationship between perceived stress and mental health 

      Lara Cabrera, Mariela Loreto; Betancort, Moisés; Muñoz-Rubilar, C. Amparo; Novo, Natalia Rodríguez; Cuevas, Carlos De las (Peer reviewed; Journal article, 2021)
      The COVID-19 pandemic has created great uncertainty around the world, and due to the pandemic, nurses have been exposed to an increase in highly stressful clinical situations. This study examines the relationships between ...

    • Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort 

      Moen, Gunn-Helen; Brumpton, Ben Michael; Willer, Cristen J.; Åsvold, Bjørn Olav; Birkeland, Kåre I.; Wang, Geng; Neale, Michael C.; Freathy, Rachel M.; Smith, George Davey; Lawlor, Debbie A.; Kirkpatrick, Robert M.; Warrington, Nicole Maree; Evans, David M. (Peer reviewed; Journal article, 2020)
      There is a robust observational relationship between lower birthweight and higher risk of cardiometabolic disease in later life. The Developmental Origins of Health and Disease (DOHaD) hypothesis posits that adverse ...

    • Meningioma Segmentation in T1-Weighted MRI Leveraging Global Context and Attention Mechanisms 

      Bouget, David Nicolas Jean-Marie; Pedersen, André; Hosainey, Sayied Abdol Mohieb; Solheim, Ole; Reinertsen, Ingerid (Peer reviewed; Journal article, 2021)
      Purpose: Meningiomas are the most common type of primary brain tumor, accounting for ~30% of all brain tumors. A substantial number of these tumors are never surgically removed but rather monitored over time. Automatic and ...